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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LANGTVMSGSHWGVFTATVENGRATAFTPWEKDPHPSPMLAGVLDSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFV
RVSWDQALDLVAAEVKRVEETYGPEGVFGGSYGWKSPGRLHNCTTLLRRMLTLAGGYVNGAGDYSTGAAQVIMPHVVGTL
EVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLEALKAKGTKVIVIDPVRTKTVEFFGAEHITPKPQT
DVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKFLPYLDGETDSTPKTAEWAEGISGVPAETIKELARLFESKRTMLAAGW
SMQRMHHGEQAHWMLVTLASMLGQIGLPGGGFGLSYHYSGGGTPSTSGPALAGITDGGAASGASVIPVARVVDMLENPGA
EFDFNGTRSKFPDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFVVHDFQWTPTARHADIVLPATTSYERNDIETIGDYS
NTGILAMKKIVEPLYEARSDYDIFAAVAERLGKGAEFTEGKDEMGWIKSFYDDAAKQGKAAGVEMPAFDAFWAEGIVEFP
VTDGADFVRYASFREDPLLNPLGTPTGLIEIYSKNIEKMGYDDCPAHPTWMEPLERLDGPGAKYPLHIAASHPFNRLHSQ
LNGTVLREGYAVQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVTDAVMKGVIQIYEGGWYDPSDVTEPGTLD
KYGDVNVLSADIGTSKLAQGNCGQTVLAEVEKYTGPAVTLTGFVAPKAAE

The query sequence (length=770) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1dmr:A 779 779 0.9987 0.9872 0.9872 0.0 1dms:A, 2dmr:A, 3dmr:A, 4dmr:A, 1e18:A, 1e5v:A, 1e5v:C, 1e60:A, 1e60:C, 1e61:A, 1e61:C, 1h5n:A, 1h5n:C
2 1eu1:A 767 768 0.7714 0.7744 0.7734 0.0
3 7l5s:A 771 767 0.5143 0.5136 0.5163 0.0 7l5i:A
4 1tmo:A 794 792 0.4740 0.4597 0.4609 0.0
5 4v4c:A 875 852 0.3325 0.2926 0.3005 1.60e-75 4v4c:C, 4v4c:E, 4v4c:G, 4v4c:I, 4v4c:K, 4v4c:M, 4v4c:O, 4v4c:Q, 4v4c:S, 4v4c:U, 4v4c:W, 4v4d:A, 4v4d:C, 4v4d:E, 4v4d:G, 4v4d:I, 4v4d:K, 4v4d:M, 4v4d:O, 4v4d:Q, 4v4d:S, 4v4d:U, 4v4d:W, 4v4e:A, 4v4e:C, 4v4e:E, 4v4e:G, 4v4e:I, 4v4e:K, 4v4e:M, 4v4e:O, 4v4e:Q, 4v4e:S, 4v4e:U, 4v4e:W
6 1fdi:A 715 682 0.2169 0.2336 0.2449 1.32e-39 1aa6:A, 1fdo:A, 2iv2:X, 7z0t:A
7 7vw6:A 913 690 0.2208 0.1862 0.2464 7.08e-32 7e5z:A, 8j83:A, 7xqw:A
8 7bkb:D 549 532 0.1597 0.2240 0.2312 1.61e-28 7bkb:d, 7bkc:D, 7bkc:d, 7bkd:D, 7bke:D
9 2vpw:A 734 740 0.2351 0.2466 0.2446 4.79e-28 2vpw:E, 2vpx:A, 2vpx:E, 2vpy:A, 2vpy:E, 2vpz:A, 2vpz:E
10 2e7z:A 727 720 0.2442 0.2586 0.2611 7.28e-28
11 7qv7:S 571 487 0.1545 0.2084 0.2444 1.18e-25 7qv7:Y
12 6tg9:A 949 677 0.2156 0.1749 0.2452 7.02e-24 6tg9:E, 6tga:A, 6tga:E
13 2v45:A 723 743 0.2364 0.2517 0.2450 1.99e-18 2jim:A, 2jio:A, 2jip:A, 2jiq:A, 2jir:A, 2nap:A, 2v3v:A
14 3ml1:A 799 792 0.2299 0.2215 0.2235 2.44e-17 3o5a:A
15 5chc:A 895 352 0.1104 0.0950 0.2415 2.05e-15 5ch7:A, 5ch7:C, 5ch7:E, 5chc:C, 5chc:E, 5e7o:A, 5e7o:C, 5e7o:E, 5e7o:G, 5e7o:I, 5e7o:K, 4ydd:A, 4ydd:C, 4ydd:E
16 5chc:A 895 217 0.0714 0.0615 0.2535 5.63e-10 5ch7:A, 5ch7:C, 5ch7:E, 5chc:C, 5chc:E, 5e7o:A, 5e7o:C, 5e7o:E, 5e7o:G, 5e7o:I, 5e7o:K, 4ydd:A, 4ydd:C, 4ydd:E
17 1ogy:A 789 763 0.2273 0.2218 0.2294 6.79e-14 1ogy:C, 1ogy:E, 1ogy:G, 1ogy:I, 1ogy:K, 1ogy:M, 1ogy:O
18 6cz7:A 814 286 0.0844 0.0799 0.2273 6.26e-10 6cz7:C, 6cz8:C, 6cz8:A, 6cz9:A, 6cz9:C, 6cza:A, 6cza:C
19 2nya:A 791 740 0.1935 0.1884 0.2014 9.17e-10 2nya:F
20 2ivf:A 912 384 0.1156 0.0976 0.2318 8.88e-09
21 2ivf:A 912 296 0.0935 0.0789 0.2432 4.54e-07
22 3egw:A 1244 266 0.0831 0.0514 0.2406 1.41e-08 3ir5:A, 3ir6:A, 3ir7:A, 1q16:A, 1r27:A, 1r27:C, 1siw:A, 1y4z:A, 1y5i:A, 1y5l:A, 1y5n:A
23 3egw:A 1244 74 0.0325 0.0201 0.3378 1.74e-06 3ir5:A, 3ir6:A, 3ir7:A, 1q16:A, 1r27:A, 1r27:C, 1siw:A, 1y4z:A, 1y5i:A, 1y5l:A, 1y5n:A
24 3egw:A 1244 126 0.0455 0.0281 0.2778 0.010 3ir5:A, 3ir6:A, 3ir7:A, 1q16:A, 1r27:A, 1r27:C, 1siw:A, 1y4z:A, 1y5i:A, 1y5l:A, 1y5n:A
25 8cff:A 823 285 0.0818 0.0765 0.2211 0.004 8cff:C, 8cff:E, 8cff:G, 8cgs:A, 8cgs:C, 8cgs:E, 8cgs:G, 8ch9:A, 8ch9:C, 8ch9:E, 8ch9:G, 1g8j:A, 1g8j:C, 1g8k:A, 1g8k:C, 1g8k:E, 1g8k:G
26 8cff:A 823 109 0.0364 0.0340 0.2569 0.58 8cff:C, 8cff:E, 8cff:G, 8cgs:A, 8cgs:C, 8cgs:E, 8cgs:G, 8ch9:A, 8ch9:C, 8ch9:E, 8ch9:G, 1g8j:A, 1g8j:C, 1g8k:A, 1g8k:C, 1g8k:E, 1g8k:G
27 1h0h:A 977 99 0.0338 0.0266 0.2626 0.013 1h0h:K
28 7b04:B 1120 73 0.0260 0.0179 0.2740 0.017 7b04:E, 7b04:H, 7b04:K, 7b04:N, 7b04:Q, 7b04:T, 7b04:W
29 7b04:B 1120 74 0.0286 0.0196 0.2973 0.023 7b04:E, 7b04:H, 7b04:K, 7b04:N, 7b04:Q, 7b04:T, 7b04:W
30 7b04:B 1120 58 0.0221 0.0152 0.2931 0.41 7b04:E, 7b04:H, 7b04:K, 7b04:N, 7b04:Q, 7b04:T, 7b04:W
31 4aay:A 843 529 0.1623 0.1483 0.2363 0.037 4aay:C, 4aay:E, 4aay:G, 8ccq:A, 8ccq:C, 8ccq:E, 8ccq:G, 8ed4:A, 8ed4:C, 8ed4:E, 8ed4:G, 5nqd:A, 5nqd:C, 5nqd:E, 5nqd:G
32 1kqf:A 982 440 0.1247 0.0978 0.2182 0.056 1kqg:A
33 7w5m:A 227 68 0.0312 0.1057 0.3529 0.12
34 8oh5:C 1172 104 0.0377 0.0247 0.2788 0.13 8oh5:F, 8oh5:I, 8oh5:L, 8oh9:C, 8oh9:F, 8oh9:I, 8oh9:L
35 5t5i:J 431 198 0.0584 0.1044 0.2273 0.34 5t5i:B, 5t5m:B, 5t61:B, 5t61:H, 5t61:N, 5t61:T, 5t61:Z, 5t61:f, 5t61:l, 5t61:r
36 6l7o:A 371 118 0.0403 0.0836 0.2627 0.49 6l7p:A
37 3pjg:A 389 67 0.0299 0.0591 0.3433 0.92 3pln:A, 3plr:A
38 6jrs:A 3488 36 0.0208 0.0046 0.4444 5.5 6jrs:D, 6jrs:G, 6jrs:J
39 6jiy:A 3521 36 0.0208 0.0045 0.4444 5.8 6ji8:A, 6ji8:D, 6ji8:G, 6ji8:J, 6jii:B, 6jii:E, 6jii:H, 6jii:K, 6jiu:A, 6jiu:D, 6jiu:G, 6jiu:J, 6jiy:D, 6jiy:G, 6jiy:J, 6jv2:A, 6jv2:C, 6jv2:E, 6jv2:G
40 7ypn:D 455 115 0.0429 0.0725 0.2870 6.3 7ypm:A, 7ypm:B, 7ypm:D, 7ypm:C, 7ypn:B
41 3pdi:A 427 49 0.0260 0.0468 0.4082 8.6 3pdi:C, 3pdi:E, 3pdi:G
42 8dfv:A 1664 75 0.0247 0.0114 0.2533 9.3

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218