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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KWKIEPFLPGPFLEESSFMTLFPKYRERYLKDCWPLVTKALEKHGIAATLDIVEGSMTVKTTRKTYDPAAILKARDLIKL
LARSVPAPQALKILEDGMACDIIKIRSMVRNKERFVKRRQRLLGQNGTTLKALELLTQTYILVHGNTVSVMGGYKGLKEV
RRVVEDTMNNIHPIYLIKELMIKRELAKDPALAHEDWSRYL

The query sequence (length=201) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6rxu:CP 233 201 1.0000 0.8627 1.0000 8.89e-151 5jpq:g, 5oql:g, 6rxt:CP, 6rxv:CP, 6rxx:CP, 6rxy:CP, 6rxz:CP
2 6ke6:RC 278 190 0.7562 0.5468 0.8000 3.32e-107 7d5s:RC, 6lqp:RC, 6lqq:RC, 6lqu:RC, 4qmf:B, 4qmf:D, 7suk:NK, 5wyj:K1, 5wyk:K1, 6zqa:JO
3 6zqb:JO 236 174 0.7015 0.5975 0.8103 8.01e-98 7ajt:JO, 6zqc:JO
4 7mq8:NY 274 193 0.6766 0.4964 0.7047 4.80e-96 7mq9:NY
5 3aev:B 177 104 0.1443 0.1638 0.2788 4.71e-11
6 7mqa:SW 195 145 0.1692 0.1744 0.2345 5.48e-05 6g18:x, 6g4s:x, 6g4w:x, 6g51:x, 6g53:x, 6g5i:x, 7mq8:SW, 7mq9:SW, 7wts:x, 7wtt:x, 7wtu:x, 7wtv:x, 7wtw:x, 7wtx:x, 7wtz:x, 7wu0:x, 6zuo:x, 6zxd:x, 6zxe:x
7 7d4i:RT 213 148 0.1592 0.1502 0.2162 5.87e-05 7ajt:JJ, 7aju:JJ, 8c00:p, 8c01:p, 8cbj:h, 7d5s:RT, 7d5t:RT, 7d63:RT, 6eml:p, 6fai:h, 6ke6:RT, 6lqp:RT, 6lqq:RT, 6lqr:RT, 6lqs:RT, 6lqt:RT, 6lqu:RT, 6rbd:h, 7suk:SO, 5wlc:SO, 7wtl:CA, 7wtm:CA, 7wtn:CA, 7wto:CA, 7wtp:CA, 7wtq:CA, 7wtr:CA, 5wyj:P1, 5wyk:P1, 6y7c:h, 6zqa:JJ, 6zqb:JJ, 6zqc:JJ, 6zqd:JJ, 6zqe:JJ, 6zqf:JJ, 6zqg:JJ
8 6rxt:CQ 175 119 0.1244 0.1429 0.2101 0.085 6rxu:CQ, 6rxv:CQ, 6rxx:CQ, 6rxy:CQ, 6rxz:CQ
9 6ola:A0 196 79 0.1095 0.1122 0.2785 0.18 6e2z:A6, 6e32:A1, 6e32:AN, 6e34:AA, 6e39:A1, 6e39:A5, 6ola:A1, 6ola:A2, 6ola:A3, 6ola:A4, 6ola:A5, 6ola:A6, 6ola:A7, 6ola:A8, 6ola:A9, 6ola:AA, 6ola:AB, 6ola:AC, 6ola:AD, 6ola:AE, 6ola:AF, 6ola:AG, 6ola:AH, 6ola:AI, 6ola:AJ, 6ola:AK, 6ola:AL, 6ola:AM, 6ola:AN, 6ola:AO, 6ola:AP, 6ola:AQ, 6ola:AR, 6ola:AS, 6ola:AT, 6ola:AU, 6ola:AV, 6ola:AW, 6ola:AX, 6ola:AY, 6ola:AZ, 6ola:Aa, 6ola:Ab, 6ola:Ac, 6ola:Ad, 6ola:Ae, 6ola:Af, 6ola:Ag, 6ola:Ah, 6ola:Ai, 6ola:Aj, 6ola:Ak, 6ola:Al, 6ola:Am, 6ola:An, 6ola:Ao, 6ola:Ap, 6ola:Aq, 6ola:Ar, 6ola:As, 6ola:At, 6ola:Au, 6ola:Av, 6ola:Aw, 6ola:Ax, 3r0r:A
10 8e7s:A 431 54 0.0846 0.0394 0.3148 1.00 8e7s:a, 8ec0:A, 8ec0:a
11 6jlz:I 430 56 0.0995 0.0465 0.3571 1.8
12 8kdb:A 2117 35 0.0746 0.0071 0.4286 3.7 8kdc:A
13 3tio:F 177 71 0.0945 0.1073 0.2676 4.5 3tio:A, 3tio:B, 3tio:C, 3tio:D, 3tio:E, 3tis:A, 3tis:B, 3tis:C
14 2iv0:A 412 32 0.0647 0.0316 0.4062 6.1 2iv0:B
15 7e5v:A 372 31 0.0697 0.0376 0.4516 8.6 7e5v:B, 7e5v:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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