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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSG

The query sequence (length=39) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8sg2:A 163 39 1.0000 0.2393 1.0000 1.97e-23 6dun:A, 6dun:B, 7efj:A, 7efx:A, 7ekv:A, 7f0m:A, 7f0m:C, 7f0m:B, 7f0m:D, 1f8a:B, 4gwv:A, 3i6c:A, 3i6c:B, 1i8g:B, 1i8h:B, 3ikd:A, 3ikd:B, 3ikg:A, 3ikg:B, 9inr:A, 9inr:B, 2itk:A, 3jyj:A, 3jyj:B, 3kab:A, 3kac:A, 3kac:B, 3kad:A, 3kaf:A, 3kag:A, 3kah:A, 3kai:A, 3kce:A, 2lb3:A, 2n1o:A, 1nmw:A, 3ntp:A, 6o33:A, 6o34:A, 3odk:A, 3oob:A, 1pin:A, 2q5a:A, 3tc5:A, 3tcz:A, 3tdb:A, 4tns:A, 4tyo:A, 4tyo:B, 5uy9:A, 6vaj:A, 3wh0:A, 2xp3:A, 2xp4:A, 2xp5:A, 2xp6:A, 2xp7:A, 2xp8:A, 2xp9:A, 2xpa:A, 2xpb:A
2 2nc3:A 33 34 0.7179 0.8485 0.8235 1.00e-14 2nc4:A, 2nc5:A, 2nc6:A
3 5dws:C 40 31 0.5128 0.5000 0.6452 1.64e-08
4 5cq2:A 76 31 0.5128 0.2632 0.6452 3.18e-08 5dws:A, 5dws:E, 5dws:G, 5dzd:A, 5dzd:B, 2jo9:A, 4rof:A, 4rof:B
5 1i5h:W 50 31 0.4103 0.3200 0.5161 4.05e-07
6 7lp3:A 37 32 0.4359 0.4595 0.5312 1.29e-06 7lp3:C
7 2laj:A 40 31 0.3590 0.3500 0.4516 3.95e-05
8 2n8t:A 39 32 0.3333 0.3333 0.4062 1.31e-04
9 2lb1:A 35 31 0.3846 0.4286 0.4839 1.67e-04 2ltx:A
10 4lcd:A 419 36 0.3846 0.0358 0.4167 1.69e-04 4lcd:B
11 7lp2:E 37 31 0.3846 0.4054 0.4839 2.56e-04 2lb2:A, 7lp2:A, 7lp2:C, 2lty:A
12 2djy:A 42 31 0.3590 0.3333 0.4516 2.96e-04
13 2ltv:A 36 31 0.3333 0.3611 0.4194 5.25e-04 2law:A
14 2kxq:A 90 31 0.3590 0.1556 0.4516 8.64e-04 2laz:A, 2lb0:A, 2ltz:A
15 2kxq:A 90 32 0.3077 0.1333 0.3750 0.14 2laz:A, 2lb0:A, 2ltz:A
16 1jmq:A 46 31 0.3590 0.3043 0.4516 0.003 1k5r:A, 1k9q:A, 1k9r:A, 2lax:A, 2lay:A, 2ltw:A
17 2m3o:W 43 31 0.3333 0.3023 0.4194 0.005 2kpz:A, 2kq0:A, 2mpt:A, 4n7h:A
18 2jmf:A 43 31 0.3077 0.2791 0.3871 0.026
19 8pxx:A 99 20 0.2564 0.1010 0.5000 0.12 2dyf:A
20 8pxx:A 99 25 0.2564 0.1010 0.4000 0.86 2dyf:A
21 6jjz:B 96 32 0.3590 0.1458 0.4375 0.14 6jjz:A, 6kkg:A, 6kkg:B
22 6jjz:B 96 31 0.2821 0.1146 0.3548 0.85 6jjz:A, 6kkg:A, 6kkg:B
23 6jjy:A 128 31 0.3077 0.0938 0.3871 0.15 6j68:A, 6j68:B, 6j69:A, 6jjw:A, 6jjx:B, 6jjx:A
24 2jup:W 37 20 0.2308 0.2432 0.4500 0.24 2rly:W, 2rm0:W
25 2oei:A 37 32 0.3590 0.3784 0.4375 0.39 2ho2:A
26 3ecq:B 1347 34 0.3077 0.0089 0.3529 0.84 5a55:A, 5a56:A, 5a57:A, 5a58:A, 5a59:A, 5a5a:A, 3ecq:A
27 2ez5:W 46 37 0.2564 0.2174 0.2703 1.0
28 8sew:A 629 27 0.2821 0.0175 0.4074 1.5 8seu:A, 8seu:B, 8seu:C, 8seu:D, 8sev:A, 8sev:B, 8sev:C, 8sev:D, 8sew:B, 8sew:C, 8sew:D, 8sex:A, 8sex:B, 8sex:C, 8sex:D, 8sey:A, 8sey:B, 8sey:C, 8sey:D, 8sez:A, 8sez:B, 8sez:C, 8sez:D, 8sf0:A, 8sf0:B, 8sf0:C, 8sf0:D
29 8duj:D 3865 27 0.2821 0.0028 0.4074 1.5
30 8duj:A 3823 27 0.2821 0.0029 0.4074 1.6
31 8duj:G 3933 27 0.2821 0.0028 0.4074 1.6
32 3j8h:A 3660 27 0.2821 0.0030 0.4074 1.7 3j8h:C, 3j8h:E, 3j8h:G
33 5gky:A 3660 27 0.2821 0.0030 0.4074 1.7 5gky:C, 5gky:E, 5gky:G, 5gkz:A, 5gkz:C, 5gkz:E, 5gkz:G, 5gl0:A, 5gl0:C, 5gl0:E, 5gl0:G, 5gl1:A, 5gl1:C, 5gl1:E, 5gl1:G
34 8dve:G 3944 27 0.2821 0.0028 0.4074 1.7 8dtb:A, 8dve:D, 8dve:A, 8dve:J
35 6x35:B 3801 27 0.2821 0.0029 0.4074 1.7 6x35:E, 6x35:H, 6x35:K
36 6x33:B 3816 27 0.2821 0.0029 0.4074 1.7 8drp:A, 8drp:B, 8drp:C, 8drp:D, 6x33:E, 6x33:H, 6x33:K
37 8duj:J 3892 27 0.2821 0.0028 0.4074 1.7
38 6w1n:B 3719 27 0.2821 0.0030 0.4074 1.7 6w1n:D, 6w1n:F, 6w1n:H, 6x34:B, 6x34:D, 6x34:F, 6x34:H
39 6x32:B 3798 27 0.2821 0.0029 0.4074 1.7 6x32:E, 6x32:H, 6x32:K
40 7umz:A 3927 27 0.2821 0.0028 0.4074 1.7 6g4s:s, 6g4w:s, 5j4z:G, 5j7y:G, 5j8k:G, 5tzs:Q, 7umz:D, 7umz:B, 7umz:C, 5wyj:UC, 5wyj:AG, 5wyk:AG, 5wyk:UC, 4wz7:A, 6xyw:AP
41 7cf9:A 3949 27 0.2821 0.0028 0.4074 1.7 7cf9:C, 7cf9:E, 7cf9:G, 8dtb:G, 8dtb:D, 6m2w:A, 6m2w:D, 6m2w:G, 6m2w:J
42 6wot:A 4197 27 0.2821 0.0026 0.4074 1.8 6wot:B, 6wot:C, 6wot:D
43 7tdg:A 4134 27 0.2821 0.0027 0.4074 1.8 7tdg:C, 7tdg:D, 7tdg:B, 7tdi:B, 7tdi:C, 7tdi:D, 7tdi:A, 7tdj:A, 7tdj:B, 7tdj:C, 7tdj:D, 7tdk:A, 7tdk:B, 7tdk:C, 7tdk:D
44 7t65:A 4252 27 0.2821 0.0026 0.4074 1.8 7t64:A, 7t64:B, 7t64:C, 7t64:D, 7t65:B, 7t65:C, 7t65:D
45 7m6a:A 4306 27 0.2821 0.0026 0.4074 1.8 7m6a:G, 7m6a:B, 7m6a:I, 7m6l:A, 7m6l:G, 7m6l:B, 7m6l:I
46 7k0s:A 4110 27 0.2821 0.0027 0.4074 1.9 7k0s:B, 7k0s:D, 7k0s:C, 7k0t:A, 7k0t:B, 7k0t:D, 7k0t:C
47 5tb3:B 4196 27 0.2821 0.0026 0.4074 1.9 7aih:UB, 7am2:U5, 7am2:U2, 7ane:UB, 7aoi:UK, 6bbm:W, 6c5l:BJ, 6c5l:DJ, 9f1c:BK, 7f4v:aJ, 7f4v:bJ, 7f4v:cJ, 6fg3:A, 6fg3:B, 6fg3:C, 6fg3:D, 1fka:Q, 1fka:T, 5gan:x, 6h8k:Y, 6h8k:j, 6hiv:AB, 6hix:AB, 5j4z:H, 5j4z:E, 5j4z:F, 5j4z:I, 5j7y:H, 5j7y:E, 5j7y:F, 5j7y:I, 5j8k:H, 5j8k:E, 5j8k:F, 5j8k:I, 6jlu:N, 6jlu:n, 7jmf:B, 7jmf:E, 7jmf:G, 7jmf:I, 7jmg:B, 7jmg:E, 7jmg:I, 7jmg:G, 7jmh:B, 7jmh:E, 7jmh:G, 7jmh:I, 7jmi:B, 7jmi:E, 7jmi:G, 7jmi:I, 7jmj:B, 7jmj:E, 7jmj:G, 7jmj:I, 5jpq:n, 5jpq:C, 7l8w:H, 5lc5:P, 5ldw:P, 5ldx:P, 7lh5:BJ, 7lh5:DJ, 5lj3:x, 5lj5:x, 5luf:E, 5luf:F, 5luf:G, 5luf:I, 5nvs:I, 5nvs:K, 5nvs:J, 5nvs:L, 5nvu:K, 5nvu:M, 5nvu:L, 5nvu:N, 2o01:K, 6o1o:B, 6o1o:C, 6o1o:D, 6o1o:E, 6o1o:I, 6o1o:J, 6o1o:K, 5o31:P, 5ot7:l, 7pkq:D, 7pkt:X, 7pkt:C, 7pub:U7, 7pub:UE, 6pv6:B, 6pv6:E, 6pv6:I, 6pv6:G, 1pyh:C, 1pyh:E, 1pyh:K, 1pyh:S, 1pyh:Y, 6q95:H, 7qwq:s, 5t15:B, 5t15:E, 5t15:I, 5t15:G, 5t9m:B, 5t9m:E, 5t9m:I, 5t9m:G, 5t9n:B, 5t9n:E, 5t9n:I, 5t9n:G, 5t9r:B, 5t9r:E, 5t9r:I, 5t9r:G, 5t9s:B, 5t9s:E, 5t9s:I, 5t9s:G, 5t9v:B, 5t9v:G, 5t9v:I, 5t9v:E, 5ta3:B, 5ta3:G, 5ta3:I, 5ta3:E, 5tal:B, 5tal:G, 5tal:I, 5tal:E, 5tam:B, 5tam:E, 5tam:I, 5tam:G, 5tan:B, 5tan:E, 5tan:I, 5tan:G, 5tap:B, 5tap:E, 5tap:I, 5tap:G, 5taq:B, 5taq:E, 5taq:I, 5taq:G, 5tas:B, 5tas:I, 5tas:E, 5tas:G, 5tat:B, 5tat:I, 5tat:E, 5tat:G, 5tau:B, 5tau:I, 5tau:E, 5tau:G, 5tav:B, 5tav:E, 5tav:I, 5tav:G, 5taw:B, 5taw:G, 5taw:I, 5taw:E, 5tax:B, 5tax:I, 5tax:G, 5tax:E, 5tay:B, 5tay:G, 5tay:I, 5tay:E, 5taz:B, 5taz:I, 5taz:G, 5taz:E, 5tb0:B, 5tb0:G, 5tb0:E, 5tb0:I, 5tb1:B, 5tb1:I, 5tb1:E, 5tb1:G, 5tb2:B, 5tb2:I, 5tb2:E, 5tb2:G, 5tb3:E, 5tb3:I, 5tb3:G, 5tb4:B, 5tb4:E, 5tb4:I, 5tb4:G, 7tdh:A, 7tdh:B, 7tdh:C, 7tdh:D, 8tug:M, 8tvp:M, 8tvq:M, 8tvs:M, 8tye:L, 5tzs:y, 5tzs:n, 5tzs:o, 4uq8:E, 4uq8:F, 4uq8:G, 4uq8:I, 4v3p:SW, 4v3p:LL, 4v5e:BJ, 4v5e:DJ, 4v5f:BJ, 4v5f:BL, 4v5f:Bl, 4v5f:DJ, 4v5f:DL, 4v5f:Dl, 4v5g:BJ, 4v5g:DJ, 4v5j:BJ, 4v5j:DJ, 4v5k:BJ, 4v5k:DJ, 4v5l:BJ, 4v5p:BJ, 4v5p:DJ, 4v5q:BJ, 4v5q:DJ, 4v5r:BJ, 4v5r:DJ, 4v5s:BJ, 4v5s:DJ, 4v6i:AW, 4v6i:Ab, 4v6i:BL, 4v7r:Ab, 4v7r:Ac, 4v7r:Ad, 4v7r:Ah, 4v7r:Bh, 4v7r:Cb, 4v7r:Cc, 4v7r:Cd, 4v7r:Ch, 4v7r:Dh, 4v8n:BJ, 4v8n:DJ, 4v8o:BJ, 4v8q:AJ, 4v8u:BJ, 4v8u:DJ, 4v8x:BJ, 4v8x:DJ, 4v90:BJ, 4v9h:BJ, 4v9h:BL, 4v9i:BJ, 4v9i:DJ, 4v9j:BJ, 4v9j:DJ, 4v9k:BJ, 4v9k:DJ, 4v9l:BJ, 4v9l:DJ, 4v9m:BJ, 4v9m:DJ, 7vd5:5, 6w1s:G, 4w29:BJ, 4w29:DJ, 8wb4:g, 8wb4:G, 5wlc:SX, 6wmt:K, 4wt8:CJ, 4wt8:DJ, 5wyj:AA, 5wyj:UA, 5wyj:UB, 5wyk:AA, 5wyk:UA, 5wyk:UB, 4wz7:Z, 4wz7:AN, 8xkl:G, 6xyw:BI, 6xyw:BJ, 6xyw:BK, 7y3f:K, 6z1p:AD, 6z1p:BC, 5zep:0, 6zm5:v
48 7tzc:A 4404 27 0.2821 0.0025 0.4074 1.9 3rqr:A, 8sen:A, 8sen:B, 8sen:C, 8sen:D, 8seo:A, 8seo:B, 8seo:C, 8seo:D, 8sep:A, 8sep:B, 8sep:C, 8sep:D, 8seq:A, 8seq:B, 8seq:C, 8seq:D, 8ser:A, 8ser:B, 8ser:C, 8ser:D, 8ses:A, 8ses:B, 8ses:C, 8ses:D, 8set:A, 8set:B, 8set:C, 8set:D, 7tzc:B, 7tzc:G, 7tzc:I
49 6foo:A 4168 27 0.2821 0.0026 0.4074 2.0 5dat:m2, 5dc3:m2, 5dgv:m2, 5fci:m2, 5fcj:m2, 6foo:B, 6foo:C, 6foo:D, 5i4l:m2, 5it7:KK, 6j3z:20, 6j3z:21, 5j4z:B, 6j40:20, 6j40:40, 6j40:21, 6j40:41, 8j5k:4, 8j5k:9, 5j7y:B, 5j8k:B, 7lh5:BK, 7lh5:DK, 5luf:B, 5lyb:m2, 5mrc:dd, 5mre:dd, 5mrf:dd, 5obm:m2, 5on6:m2, 5ot7:m, 7pkq:V, 7pkt:Y, 6q95:I, 5tga:m2, 5tzs:Z, 5tzs:m, 4u3m:m2, 4u3n:m2, 4u3u:m2, 4u4n:m2, 4u4o:m2, 4u4q:m2, 4u4r:m2, 4u4u:m2, 4u4y:m2, 4u4z:m2, 4u50:m2, 4u51:m2, 4u52:m2, 4u53:m2, 4u55:m2, 4u56:m2, 4u6f:m2, 4uq8:B, 6uz7:AK, 4v3p:SG, 4v5g:BK, 4v5g:DK, 4v5l:BK, 4v5p:BK, 4v5p:DK, 4v5q:BK, 4v5q:DK, 4v5r:BK, 4v5r:DK, 4v5s:BK, 4v5s:DK, 4v6i:AG, 4v88:DK, 4v8o:BK, 4v8q:AK, 4v8t:K, 4v8y:BK, 4v8z:BK, 4v90:BK, 8w4p:4, 6woo:K, 7y1a:A, 7y5e:A8, 7y5e:AC, 7y7a:AN, 7y7a:AY, 5z3g:d
50 8vk4:D 4379 27 0.2821 0.0025 0.4074 2.0 8vjj:A, 8vjj:D, 8vjj:B, 8vjj:C, 8vjk:A, 8vjk:B, 8vjk:C, 8vjk:D, 8vk3:A, 8vk3:D, 8vk3:B, 8vk3:C, 8vk4:A, 8vk4:B, 8vk4:C
51 1eg4:A 260 27 0.2564 0.0385 0.3704 2.0
52 9bh5:CW 88 20 0.2308 0.1023 0.4500 3.0 9cai:CW
53 7lbm:d 275 24 0.2564 0.0364 0.4167 5.5 8byq:7
54 7enc:0 306 24 0.2564 0.0327 0.4167 5.5 1g25:A, 8gxq:HD, 8gxs:HD, 6nmi:H, 7nvw:3, 7nvx:3, 7nvy:3, 7nvz:3, 8wak:0, 8wal:0, 8wan:0, 8wao:0, 8wap:0, 8waq:0, 8war:0, 8was:0
55 7nvr:3 214 24 0.2564 0.0467 0.4167 5.7
56 1p4e:B 413 38 0.3333 0.0315 0.3421 6.0 1flo:A, 1flo:D, 1flo:B, 1flo:C, 1m6x:A, 1m6x:C, 1m6x:D, 1m6x:B, 1p4e:A, 1p4e:C, 1p4e:D
57 7egb:0 236 24 0.2564 0.0424 0.4167 6.2 7egc:0
58 2ky8:A 70 27 0.2821 0.1571 0.4074 7.5
59 7mwm:A 74 27 0.2821 0.1486 0.4074 8.1 6c1a:A, 6c1a:B, 6c1a:E, 6c1a:F, 6c1t:A, 6c1t:D, 6c1u:A, 6c1u:B, 6c1u:E, 6c1u:F, 6c1v:A, 6c1v:B, 6c1v:E, 6c1v:F, 6c2f:A, 6c2f:D, 6c2f:G, 6c2f:J, 6c2f:M, 6c2f:P, 6cnp:A, 6cnp:B, 6cnq:A, 6cnq:B, 7mwk:A, 7mwk:B, 7mwm:B, 7ray:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218