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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KDVRIARWVATIAGLLGFVLSVSIPLLPVTQTTATLNWPQQGRLDNVTAPLISQAPLELTATVPCSVVRDLPPEGGLVFG
TAPAEGRDAALNAMLVNVTETRVDVIVRNVVVASVNRDRVAGPDCQRIEITSNLDGTYADFVGLTQISGEDAGKLQRTGY
PDPNLRPAIVGVFTDLTGPAPQGLSVSAEIDTRFTTHPTALKLAAMLLAIVSTVIALLALWRLDRLDGRRMHRLIPTRWR
TVTAVDGVVVGGMAIWYVIGANSSDDGYILQMARTAEHAGYMANYFRWFGSPEDPFGWYYNVLALMTKVSDASIWIRLPD
LICALICWLLLSREVLPRLGPAVAGSRAAMWAAGLVLLGAWMPFNNGLRPEGQIATGALITYVLIERAVTSGRLTPAALA
ITTAAFTLGIQPTGLIAVAALLAGGRPILRIVMRRRRLVGTWPLIAPLLAAGTVILAVVFADQTIATVLEATRIRTAIGP
RVAFVFTAMCLFPSLFMMLRRKHIAGVARGPAWRLMGIIFATMFFLMFTPTKWIHHFGLFAAVGGAMAALATVLVSPTVL
RSARNRMAFLSLVLFVLAFCFASTNGWWYVSNFGAPFNNSVPKVGGVQISAIFFALSAIAALWAFWLHLTRRTESRVVDR
LTAAPIPVAAGFMVVVMMASMAIGVVRQYPTYSNGWANIRAFAGGCGLADDVLVEPDSNAGFLTPLPGAYGPLGPLGGED
PQGFSPDGVPDRIIAEAIRLNNPQPGTDYDWNRPIKLDEPGINGSTVPLPYGLDPKRVPVAGTYSTEAQQESRLSSAWYE
LPARDETERAAHPLVVITAAGTITGESVANGLTTGQTVDLEYATRGPDGTLVPAGRVTPYDVGPTPSWRNLRYPRSEIPD
DAVAVRVVAEDLSLSQGDWIAVTPPRVPELQSVQEYVGSDQPVLMDWAVGLAFPCQQPMLHANGVTEVPKFRISPDYYAK
LQSTDTWQDGINGGLLGITDLLLRASVMSTYLSQDWGQDWGSLRKFDTVVEATPAELDFGSQTHSGLYSPGPLRIRP

The query sequence (length=1037) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6x0o:A 1037 1037 1.0000 1.0000 1.0000 0.0
2 7bvc:B 1063 1062 1.0000 0.9755 0.9765 0.0 7bvg:B, 7bwr:A
3 7bvf:B 1054 1066 0.6972 0.6860 0.6782 0.0
4 7bvh:A 1035 1077 0.4687 0.4696 0.4513 0.0 7bve:A, 7bve:B, 7bvh:B
5 7bvc:A 1078 1092 0.4127 0.3970 0.3919 0.0 7bvg:A
6 3pty:A 284 336 0.1302 0.4754 0.4018 7.08e-64
7 3byw:C 160 169 0.0473 0.3063 0.2899 1.84e-14 3byw:B, 3byw:D, 3byw:E, 3byw:F, 3byw:G
8 1jro:B 760 84 0.0231 0.0316 0.2857 0.75 1jro:D, 1jro:F, 1jro:H, 1jrp:B, 1jrp:D, 1jrp:F, 1jrp:H, 2w3r:B, 2w3r:D, 2w3r:F, 2w3r:H, 2w3s:B, 2w3s:D, 2w3s:F, 2w3s:H, 2w54:B, 2w54:D, 2w54:F, 2w54:H, 2w55:B, 2w55:D, 2w55:F, 2w55:H
9 7c8z:A 383 90 0.0203 0.0548 0.2333 0.84 7c8z:C, 7c8z:E, 7c8z:G
10 2j3l:B 570 55 0.0193 0.0351 0.3636 6.3 2j3l:A, 2j3m:A, 2j3m:B
11 4u4t:A 444 51 0.0154 0.0360 0.3137 9.2 4u4w:A, 4u4w:B
12 4jr9:A 409 51 0.0154 0.0391 0.3137 9.9 4jre:A, 4jre:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218