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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HVLKTKDVDTVFVERQKKVLSLFQDVDQLNTNDEYYKIGKDYDIEANIDNYTNKKAVEDFLKMYRCGFLPKYNEFSVFHD
KLRDEAIALFHLFYYAKDFDTFYKSAAFARVHLNQGQFLYAYYIAIIQRKDTYGIVLPAPYEIYPELFVNIDTTYKMFRT
KMQNGLINPEAAVEYGIVKEDNHYVYYSNYSNAITYYNEEQRLAYFTEDIGLNAYYFFFHIHLPFWWTAEKYGNLKERRG
EMYHYFYDQLLTRYYFERLTNGLGTIPEFSWYSPVKTGHYPLLTSYYTPFSQRPNFYNVHSEENYEKIRFLDAYENYFVQ
ALQKGVFEGFGQTIYLNDSKANSFVGNYWQDNADLYGEEVTKDYQRSYEIVARQVLGAAPKPFDKYTFMPSALDFYQTSL
RDPTFYQLYNRIIGYFNQFKQYLEPHSQEKLHFVGVKVNNVVVDKLVTFFEYYDFDATNTVFLTEEELKTKYPHNLKVRQ
PRLNHQPFNINIDIKADVATDAVVKIFMGPKYNENGFPITLENDWMKFFEMDWFTHKITPGQNTIVRNSNEFVIFKEDSL
PSTELYKLLEKGKVPFDMSEDFGYLPKRLMLPRGTKGGFPFQFVVFVYPFESTTKNLTPYEKFMIDNKPLGYPFDRPVDT
SCFKQPNIFFRDVSVYHEGEYHAYEYNVPAYFSH

The query sequence (length=674) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3gwj:D 674 674 1.0000 1.0000 1.0000 0.0 3gwj:A, 3gwj:F, 3gwj:B, 3gwj:E, 3gwj:C
2 8ca9:A 680 666 0.5430 0.5382 0.5495 0.0 8ca9:B, 8ca9:C, 8po9:D, 8po9:A, 8po9:B, 8po9:C, 8po9:E, 8po9:F
3 8ca9:D 678 664 0.5460 0.5428 0.5542 0.0 8ca9:E, 8ca9:F
4 8can:A 683 633 0.3234 0.3192 0.3444 2.69e-110 8can:B, 8can:C, 8can:D, 8can:E, 8can:F
5 8cad:A 636 658 0.2967 0.3145 0.3040 9.06e-90 8cad:B, 8cad:C, 8cad:D, 8cad:E, 8cad:F
6 6l8s:A 650 661 0.2789 0.2892 0.2844 3.02e-75 1hc1:A, 1hc1:B, 1hc1:C, 1hc1:D, 1hc1:E, 1hc1:F, 6l8s:B, 6l8s:C
7 1hcy:A 644 601 0.2611 0.2733 0.2928 4.20e-69
8 1nol:A 607 611 0.2389 0.2652 0.2635 2.27e-61 1ll1:A, 1lla:A
9 1oxy:A 573 620 0.2374 0.2792 0.2581 1.96e-59
10 8jib:E 661 631 0.2389 0.2436 0.2552 1.29e-50 8ji8:A, 8ji8:B, 8ji8:C, 8ji8:D, 8jib:A, 8jib:B, 8jib:C, 8jib:D, 8jib:F, 8jib:G, 8jib:H, 8jib:I, 8jib:J, 8jib:K, 8jib:L
11 3hhs:B 656 621 0.2315 0.2378 0.2512 2.39e-50
12 3hhs:A 669 611 0.2315 0.2332 0.2553 3.93e-46
13 4yzw:B 682 622 0.2255 0.2229 0.2444 2.03e-42 4yzw:A
14 3wky:A 655 639 0.2211 0.2275 0.2332 4.85e-33 3wky:B
15 5yy2:A 569 487 0.1588 0.1880 0.2197 3.78e-06
16 6z1p:Bc 159 169 0.0623 0.2642 0.2485 3.2
17 4ktp:A 767 111 0.0401 0.0352 0.2432 3.6 4ktp:B, 4ktr:A, 4ktr:D, 4ktr:E, 4ktr:F, 4ktr:G, 4ktr:H
18 7bng:A 96 41 0.0208 0.1458 0.3415 4.2
19 8wnf:A 918 87 0.0341 0.0251 0.2644 4.9 8wng:A, 8wni:A, 8wnj:A, 8wo2:A, 8wo3:A
20 5ks7:A 123 31 0.0208 0.1138 0.4516 5.2 5ks7:B
21 4ovr:A 298 99 0.0401 0.0906 0.2727 8.4 4ovr:B
22 6wao:B 406 97 0.0341 0.0567 0.2371 9.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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