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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HNFTYWNPTKLIFGRGEVERLPEELKSYGKNVLLVYGGGSIKRSGLYDQVIEQLNKAGVTVHELAGVEPNPRVSTVNKGV
ALCKEHHIDFLLAVGGGSVIDCTKAIAAGAKYDGDAWDIVTKKHQPKDALPFGTVLTLAATGSEMNSGSVITNWETKEKY
GWGSPLVFPKFSILDPVNTFTVPKNHTIYGMVDMMSHVFEQYFHHVSNTPYQDRMCESLLRTVIETAPKLINDLENYELR
ETILYTGTIALNGMLSMGARGDWATHNIEHAVSAVYDIPHAGGLAILFPNWMRHTLSENPARMKQLAVRVFGVEEAGKTD
KEVALEGIDKLSAFWTSLGAPNRLADYDINDEQLDTIADKAMAQFKSLNKEDVLAILKASL

The query sequence (length=381) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7w9y:A 389 386 1.0000 0.9794 0.9870 0.0 7w9y:B, 7w9y:C, 7w9y:D, 7w9z:A, 7w9z:B
2 1vlj:B 400 393 0.4541 0.4325 0.4402 2.16e-109 1vlj:A
3 7fjg:A 384 387 0.4042 0.4010 0.3979 2.49e-97 8i29:A
4 1oj7:A 390 363 0.3727 0.3641 0.3912 2.18e-82 1oj7:B, 1oj7:C, 1oj7:D, 4qgs:A
5 3bfj:A 382 386 0.2756 0.2749 0.2720 9.22e-39 3bfj:B, 3bfj:C, 3bfj:D, 3bfj:E, 3bfj:F, 3bfj:G, 3bfj:H, 3bfj:I, 3bfj:J, 3bfj:K, 3bfj:L, 3bfj:M, 3bfj:N, 3bfj:O, 3bfj:P, 3bfj:Q, 3bfj:R, 3bfj:S, 3bfj:T
6 3owo:A 382 359 0.2651 0.2644 0.2813 3.31e-36 3owo:B, 3owo:C, 3owo:D, 3ox4:A, 3ox4:B, 3ox4:C, 3ox4:D
7 5yvm:A 403 395 0.2940 0.2779 0.2835 4.56e-36 5yvr:A, 5yvs:A
8 1vhd:A 361 308 0.2178 0.2299 0.2695 4.71e-27 1o2d:A, 1o2d:B, 1vhd:B
9 6c75:A 378 367 0.2598 0.2619 0.2698 8.81e-25 6c75:B, 6c76:A, 6c7l:A
10 5br4:A 385 365 0.2388 0.2364 0.2493 2.84e-24 2bi4:A, 2bi4:B, 2bl4:A, 2bl4:B, 5br4:B, 7qlg:AAA, 7qlg:BBB, 7qlq:AAA, 7qlq:BBB, 7qls:AAA, 7qls:BBB, 7qnf:AAA, 7qnf:BBB, 7qnh:AAA, 7qnh:BBB, 7qnj:AAA, 7qnj:BBB, 7r0p:AAA, 7r0p:BBB, 7r3d:AAA, 7r3d:BBB, 7r5t:AAA, 7r5t:BBB, 1rrm:A, 1rrm:B
11 3zdr:A 403 311 0.2205 0.2084 0.2701 6.82e-24
12 6jko:A 376 351 0.2257 0.2287 0.2450 1.21e-23 6jko:B, 6jko:C, 6jko:D, 6jkp:A, 6jkp:B, 6jkp:C, 6jkp:D
13 8uhw:B 859 387 0.2388 0.1059 0.2351 1.52e-19 8uhw:C, 8uhw:D, 8uhw:E
14 7bvp:A 869 333 0.2231 0.0978 0.2553 1.61e-19 7bvp:B, 7bvp:C, 7bvp:D, 7bvp:E, 7bvp:F, 6scg:A, 6scg:B, 6sci:A, 6sci:B, 6tqh:A, 6tqh:B, 6tqm:B, 6tqm:A
15 3jzd:A 354 380 0.2336 0.2514 0.2342 4.33e-18 3jzd:B, 3jzd:C, 3jzd:D
16 3hl0:A 351 366 0.2362 0.2564 0.2459 2.61e-12 3hl0:B
17 8uhw:F 293 248 0.1522 0.1980 0.2339 2.81e-11
18 1kq3:A 364 406 0.2388 0.2500 0.2241 0.023
19 3uhj:A 357 103 0.0814 0.0868 0.3010 0.081 3uhj:B, 3uhj:C, 3uhj:D, 3uhj:E, 3uhj:F, 3uhj:G, 3uhj:H
20 4mca:A 367 199 0.1207 0.1253 0.2312 0.26 4mca:B
21 5fb3:F 337 125 0.0814 0.0920 0.2480 0.40 5fb3:A, 5fb3:B, 5fb3:C, 5fb3:D, 5fb3:E
22 3rf7:A 362 202 0.1129 0.1188 0.2129 0.50
23 7djs:D 251 69 0.0551 0.0837 0.3043 0.55 7djs:A, 7djs:B, 7djs:C
24 5k8c:A 358 259 0.1391 0.1480 0.2046 2.4
25 5en1:A 184 95 0.0656 0.1359 0.2632 3.0 8hni:A, 8hni:B, 8hni:G, 8hni:I, 8hni:H, 8hni:E, 8hni:K, 8hni:C, 8hni:D, 8hni:J, 8hni:F, 8hni:L, 5ho4:A, 7wm3:A, 7wm3:B, 7wm3:C, 7wm3:D, 5wwe:A, 5wwf:A, 5wwf:C, 5wwg:A
26 8goa:A 367 101 0.0682 0.0708 0.2574 4.1 8goa:B, 8goa:C, 8goa:D, 8gob:A, 8gob:B, 8x6m:A, 8x6m:B, 5zxl:A, 5zxl:B, 5zxl:C, 5zxl:D
27 4a2m:B 750 102 0.0682 0.0347 0.2549 4.3 4a2l:E, 4a2m:A, 4a2m:C, 4a2m:D
28 8fcy:A 2864 58 0.0499 0.0066 0.3276 4.4 8fd6:A, 8fdt:A
29 8dyu:A 2562 58 0.0499 0.0074 0.3276 4.4 8dyv:A
30 5nug:A 2920 58 0.0499 0.0065 0.3276 4.6 5nug:B
31 8pqw:A 2892 58 0.0499 0.0066 0.3276 4.6 8pqy:A, 8pqz:A, 8pqz:J
32 7z8g:A 3047 58 0.0499 0.0062 0.3276 4.8 8fdu:A, 7z8l:f
33 1jq5:A 366 103 0.0525 0.0546 0.1942 5.0 1jpu:A, 1jqa:A
34 5k7u:A 208 49 0.0367 0.0673 0.2857 5.0 7acd:A, 8bn8:AAA, 5il1:A, 5il2:A, 5k7w:A, 5l6d:A, 5l6e:A, 7nhg:A, 7nhh:A, 7nhi:A, 7nhj:A, 7nhv:A, 7ni7:A, 7ni8:A, 7ni9:A, 7nia:A, 7nid:A, 7o08:A, 7o09:A, 7o0l:A, 7o0m:A, 7o0p:A, 7o0q:A, 7o0r:A, 7o27:A, 7o28:A, 7o29:A, 7o2e:A, 7o2f:A, 7o2h:A, 7o2i:A, 7o2x:A, 7oed:A, 7oee:A, 7oef:A, 7oeg:A, 7oeh:A, 7oei:A, 7oej:A, 7oek:A, 7oel:A, 7oem:A, 7oql:A, 7oqo:A, 7oqp:A, 8pw8:A, 8pw9:A, 8pwa:A, 8pwb:A, 5tey:A, 6ttp:A, 6ttt:A, 6ttv:A, 6ttw:A, 6ttx:A, 6tu1:A, 6y4g:A
35 6c66:M 244 71 0.0630 0.0984 0.3380 5.3 5u07:N, 5u0a:N
36 8ptk:f 4502 58 0.0499 0.0042 0.3276 6.1 8ptk:e
37 8iuf:1A 352 80 0.0525 0.0568 0.2500 6.3 8j9h:1A, 8j9i:1A, 8j9j:1A
38 7z8f:e 4579 58 0.0499 0.0041 0.3276 6.5 5owo:A, 8pr2:f, 8ptk:m, 8ptk:n, 7z8f:f, 7z8f:m, 7z8f:n, 7z8h:A
39 3dan:A 473 76 0.0656 0.0529 0.3289 7.0 3dam:A, 3dbm:A
40 8k1g:A 367 102 0.0709 0.0736 0.2647 7.0 8k1h:A
41 6o8w:0 58 23 0.0262 0.1724 0.4348 7.1 7nhk:2, 6o8x:0, 6o8y:0, 6o8z:0, 6o90:0, 7p7q:2, 7p7r:2, 7p7s:2, 7p7t:2, 7p7u:2, 6w6p:0, 6wu9:0
42 4o8m:A 303 32 0.0341 0.0429 0.4062 8.3 4o8m:B, 4o8m:C, 4o8m:D, 4o8m:E, 4o8m:F, 4o8m:G, 4o8m:H
43 8q3b:A 1423 37 0.0315 0.0084 0.3243 8.9 8q3k:A
44 2ohh:A 403 116 0.0814 0.0769 0.2672 9.2 2ohh:B, 2ohh:D, 2ohh:E, 2ohi:A, 2ohi:B, 2ohi:D, 2ohi:E, 2ohi:G, 2ohi:H, 2ohi:I, 2ohi:J, 2ohj:A, 2ohj:B, 2ohj:D, 2ohj:E
45 1khw:B 497 23 0.0289 0.0221 0.4783 9.4 1khw:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218