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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMRIAVIGGGSSYTPELVKGLLDISEDVRIDEVIFYDIDEEKQKIVVDFVKRLVKDRFKVLISDTFEGAVVDAKYVIFQF
RPGGLKGRENDEGIPLKYGLIGQETTGVGGFSAALRAFPIVEEYVDTVRKTSNATIVNFTNPSGHITEFVRNYLEYEKFI
GLCNVPINFIREIAEMFSARLEDVFLKYYGLNHLSFIEKVFVKGEDVTEKVFENLKLKLPDEDFPTWFYDSVRLIVNPYL
RYYLMEKKMFKKISTHELRAREVMKIEKELFEKYRTAVEIPEELTKRGGSMYSTAAAHLIRDLETDEGKIHIVNTRNNGS
IENLPDDYVLEIPCYVRSGRVHTLSQGKGDHFALSFIHAVKMYERLTIEAYLKRSKKLALKALLSHPLGPDVEDAKDLLE
EILEANREYVKLG

The query sequence (length=413) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1up7:A 414 413 0.9976 0.9952 0.9976 0.0 1up6:A, 1up6:C, 1up6:G, 1up7:B, 1up7:C, 1up7:D, 1up7:E, 1up7:F, 1up7:G, 1up7:H
2 5c3m:B 411 422 0.3801 0.3820 0.3720 2.08e-80 5c3m:A, 5c3m:C, 5c3m:D
3 6wbt:A 442 437 0.3390 0.3167 0.3204 6.44e-60 6wbt:B, 6wbt:C, 6wbt:D
4 6vc6:B 440 438 0.3027 0.2841 0.2854 1.56e-48 6vc6:A, 6vc6:C, 6vc6:D
5 1u8x:X 436 425 0.2857 0.2706 0.2776 2.34e-46
6 6dvv:A 435 440 0.2978 0.2828 0.2795 3.83e-44 6dux:A, 6dux:B, 6dvv:B
7 3fef:A 434 439 0.2615 0.2488 0.2460 6.95e-16 3fef:B, 3fef:C, 3fef:D
8 1vjt:A 471 471 0.2615 0.2293 0.2293 1.39e-12 7br4:A, 7brf:A, 7ctl:A, 7ctm:A, 6kcx:A, 3u95:A, 3u95:B, 3u95:C, 3u95:D, 3u95:E, 3u95:F
9 1obb:A 478 215 0.1259 0.1088 0.2419 0.034 1obb:B
10 1obb:A 478 107 0.0654 0.0565 0.2523 0.095 1obb:B
11 6sms:A 724 53 0.0387 0.0221 0.3019 1.8
12 8am6:AAA 547 86 0.0557 0.0420 0.2674 1.9 8am3:AAA, 8am3:BBB, 8am6:BaB, 8am8:BBB, 8am8:AAA
13 2o03:A 129 60 0.0412 0.1318 0.2833 1.9
14 7azq:A 199 104 0.0605 0.1256 0.2404 1.9 7azq:E, 7azr:A, 7azr:E
15 3iu6:A 143 88 0.0581 0.1678 0.2727 2.3
16 8vsi:B 579 75 0.0460 0.0328 0.2533 2.7
17 7s8t:J 83 48 0.0412 0.2048 0.3542 5.1 7s8t:A, 7s8t:E, 7s8t:F, 7s8t:H, 7s8t:G, 7s8t:I
18 1civ:A 374 169 0.1041 0.1150 0.2544 6.2
19 5egj:A 167 53 0.0412 0.1018 0.3208 6.5 5egl:A, 5egl:B, 5egl:C
20 7wbb:F 699 88 0.0581 0.0343 0.2727 7.2
21 1igt:B 444 20 0.0291 0.0270 0.6000 7.7 1igt:D, 2otu:B, 2otu:D, 2otu:F, 2otu:H, 2otw:B, 2otw:D, 2qhr:H, 6uqc:C, 6uqc:D, 6uqc:F, 5vaa:A, 5vaa:B, 3zo0:A
22 9j0u:A 286 30 0.0363 0.0524 0.5000 8.5 9j0v:A
23 5an9:A 398 115 0.0678 0.0704 0.2435 9.5 5anb:A, 5anc:A, 6qkl:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218