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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HIWSDFTTRPSSLSIQSSKVKNYLFQPSISRRSNRIKYSPPEHIDEIFRMSYDFLEQRSSKFYENPLKKDALLIKAEINN
PEVQYNFQFNNKLNNVKDIIDYDVPVYRHLGKQHWESYGQMLLMQRLETLAAIPDTLPTLVPRAEVNIKFPFSTGVNKWI
EPGEFLSSNVTSMRPIFKIQEYELVNVEKQLYTVLIVNPDVPDLSNDSFKTALCYGLVNINLTYNDNLIDPRKFHSSNII
ADYLPPVPEKNAGKQRFVVWVFRQPLIQGPNMLEIDRKELSRDDFDIRQFTKKYNLTAIGAHIWRSEWDAKVAAVREKYG
LPPGRVFSRVRR

The query sequence (length=332) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5mrc:1 348 348 1.0000 0.9540 0.9540 0.0 3j6b:1, 5mre:1, 5mrf:1
2 6ywe:1 367 260 0.2139 0.1935 0.2731 8.97e-30 6yws:1, 6ywv:1, 6ywx:1, 6ywy:1
3 1b7a:A 186 136 0.1145 0.2043 0.2794 1.00e-07 1a44:A, 1b7a:B, 1beh:A, 1beh:B, 2qyq:A
4 2iqx:C 186 132 0.1024 0.1828 0.2576 1.95e-07 2iqx:A, 2iqx:B
5 6igj:A 167 167 0.1295 0.2575 0.2575 1.03e-04
6 7o9k:6 331 182 0.1325 0.1329 0.2418 0.052 7a5f:63, 7a5g:63, 7a5h:6, 7a5i:63, 7a5j:6, 7a5k:63, 3j7y:6, 3j9m:6, 6nu2:6, 6nu3:6, 7o9m:6, 7of0:6, 7of2:6, 7of3:6, 7of4:6, 7of5:6, 7of6:6, 7of7:6, 7oi6:6, 7oi7:6, 7oi8:6, 7oi9:6, 7oia:6, 7oib:6, 7oic:6, 7oid:6, 7oie:6, 5ool:6, 5oom:6, 7pd3:6, 7qh6:6, 8qu5:6
7 7qh7:6 292 180 0.1295 0.1473 0.2389 0.072
8 8any:6 354 84 0.0602 0.0565 0.2381 0.25 6i9r:6, 8k2a:Ll, 8k2b:Ll, 7l08:6, 7l20:6, 7odr:6, 7ods:6, 7odt:6, 7og4:6, 8oir:Bn, 8oit:Bn, 8pk0:6, 7po4:6, 7qi4:6, 7qi5:6, 7qi6:6, 8qsj:6, 8qu1:6, 6vlz:6, 6vmi:6, 8xt0:Ll, 8xt1:Ll, 8xt2:Ll, 8xt3:Ll, 6zm5:6, 6zm6:6, 6zs9:6, 6zsa:6, 6zsb:6, 6zsc:6, 6zsd:6, 6zse:6, 6zsg:6
9 7aih:X 468 176 0.1265 0.0897 0.2386 0.56 7ane:X
10 6hiv:Ab 453 28 0.0301 0.0221 0.3571 1.1 6hix:Ab
11 5aj4:Bb 354 211 0.1386 0.1299 0.2180 1.2 6gaw:Bb, 6gb2:Bb, 7nqh:Bb, 7nql:Bb, 7nsh:Bb, 7nsi:Bb, 7nsj:Bb, 8oin:Bn, 8oiq:Bn, 6ydp:Bb, 6ydw:Bb
12 8hfd:A 452 120 0.0753 0.0553 0.2083 1.2 3e74:B, 8hfd:B, 8hfd:C, 8hfd:D
13 8h4x:A 330 60 0.0572 0.0576 0.3167 3.8
14 1e1d:A 553 62 0.0542 0.0325 0.2903 5.0 1e2u:A, 1e9v:A, 1gnt:A, 1oa1:A, 1w9m:A
15 2wyh:A 905 43 0.0392 0.0144 0.3023 7.0 2wyh:B, 2wyi:A, 2wyi:B
16 5a31:O 685 76 0.0602 0.0292 0.2632 8.2 5lcw:O, 6tlj:O, 4ui9:O

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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