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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GSEGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRSQASRPTPD
ELEAVRKYFQLDVTLAQLYHHWGSVDSHFQQVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLI
QLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARCVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVA
DWICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLR

The query sequence (length=313) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xhi:A 316 313 0.9744 0.9652 0.9744 0.0 7ayy:AAA, 7ayy:BBB, 7ayy:CCC, 7ayy:DDD, 7ayy:EEE, 1ebm:A, 1fn7:A, 1hu0:A, 2i5w:A, 3ih7:A, 3ktu:A, 1lwv:A, 1lww:A, 1lwy:A, 1m3h:A, 1m3q:A, 1n39:A, 1n3a:A, 1n3c:A, 2nob:A, 2noe:A, 2nof:A, 2noh:A, 2noi:A, 2nol:A, 2noz:A, 6rlw:AAA, 6rlw:BBB, 6rlw:CCC, 6rlw:DDD, 6rlw:EEE, 6w0m:A, 6w0r:A, 6w13:A, 1yqk:A, 1yql:A, 1yqm:A, 1yqr:A
2 8bvx:A 316 312 0.8626 0.8544 0.8654 0.0 7ayz:AAA, 7ayz:BBB, 7ayz:CCC, 7az0:AAA, 7az0:BBB, 8bq7:A, 8cex:A, 8cey:A, 8cey:B, 8cey:C, 6g3y:A, 6g3y:B, 6g3y:C, 6g40:A, 6g40:B, 6g40:C, 7pz1:AAA, 7qel:AAA, 7qel:BBB, 7qel:CCC, 7z3y:AAA, 7z5b:A, 7z5b:B, 7z5b:C, 7z5r:A, 7z5r:B, 7z5r:C, 7zc7:A, 7zc7:B, 7zc7:C, 7zg3:A, 7zg3:B, 7zg3:C
3 3f10:A 292 292 0.2428 0.2603 0.2603 8.00e-25 3i0w:A, 3i0x:A
4 4ejy:A 289 286 0.2620 0.2837 0.2867 1.26e-24 4ejy:B, 4ejz:A, 4ejz:B
5 4uob:A 242 100 0.1182 0.1529 0.3700 3.78e-05 8a5g:A
6 8a5c:A 237 74 0.0799 0.1055 0.3378 0.016 8a5f:A, 4unf:A
7 3ogd:A 288 108 0.1086 0.1181 0.3148 0.087 3cvs:A, 3cvs:B, 3cvs:C, 3cvs:D, 3cvt:A, 3cvt:B, 3cvt:C, 3cvt:D, 3cw7:A, 3cw7:B, 3cw7:C, 3cw7:D, 3cwa:A, 3cwa:B, 3cwa:C, 3cwa:D, 3cws:A, 3cws:B, 3cws:C, 3cws:D, 3cwt:A, 3cwt:B, 3cwt:C, 3cwt:D, 3cwu:A, 3cwu:B, 3cwu:C, 3cwu:D, 3d4v:A, 3d4v:B, 3d4v:C, 3d4v:D, 1diz:B, 1diz:A, 3oh6:A, 3oh9:A, 1pvs:A, 1pvs:B
8 8wa0:B 973 39 0.0383 0.0123 0.3077 0.41 8w9z:B
9 8wa1:B 998 39 0.0383 0.0120 0.3077 0.42
10 7ef9:A 414 123 0.1118 0.0845 0.2846 0.50 7ef8:A
11 7t18:A 439 168 0.1278 0.0911 0.2381 0.51 2aq4:A, 3bjy:A, 3osp:A, 7t19:A, 7t1a:A, 7t1b:A, 5wm1:A, 5wm8:A, 5wmb:A, 6x6z:A, 6x70:A, 6x71:A, 6x72:A, 6x73:A, 6x74:A, 6x75:A, 6x76:A, 6x77:A
12 4p1v:C 291 47 0.0543 0.0584 0.3617 0.93 4p1v:A, 4p1v:B, 4p1v:D, 4p25:A, 4p25:B, 4p25:C, 4p25:D, 4p2n:B, 4p2n:A, 4p2n:C, 4p2n:D, 4p3i:A, 4p3i:B, 4p3i:C, 4p3i:D
13 7y5e:72 164 51 0.0479 0.0915 0.2941 1.7 7y5e:7N, 7y7a:77, 7y7a:7o
14 7rds:A 232 91 0.0895 0.1207 0.3077 3.3 7rdt:A
15 6vvt:C 883 40 0.0511 0.0181 0.4000 4.4
16 1bxn:A 445 42 0.0447 0.0315 0.3333 7.6 1bxn:C, 1bxn:E, 1bxn:G
17 7xjn:A 322 77 0.0767 0.0745 0.3117 8.5 7xjn:B, 7xjn:C, 7xjn:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218