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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GILKTLSAPIILENSNSTFTFLPGGDNFEWIHESIMINAFQGNTLDGSTNNLYLRIYKDNSLAFYPLIGMNSKSTIKSGT
STLIFEGTAEDISYTVTFRLTPYGIWFWDISLSGNCNKADIIYSQDIGVGTKGSVNSNELYLAQYLGHSIFQGDYGYVIC
SRQNMAQGDLFPYLQQGSLGIRSIAYSTDGTQFFGLSYKKTNIPEALYGDLPSKNKQYELAHTALQTEAFSLSGTKQFSF
YGICKTNHPEVIREIEYIQELEKAYAYHESGEILPVNVPTLQNIGAPYASSRWDAKQVEHYFPKRLLEEKEEEALLSFFT
PEKSHVVLQDKELTTERPHGHILMTNFDVTKVPQGVVSSTNYMYGAFNCQFVVGNTTYNKLLSNHRGLLNIQKDSGQRIF
IKIGDCYRQLTLPAAYEMNVAGSTWYYQLDEDVLIITSFAMYNRPEIVLKVQSLGHKKYDFIVTHQLTVGPNEYENEIKL
TREGNILQLSPTDPVVTNHFYPELSFRMRIPEDCTLSDDSIFFHNNTTINPSLLSIEILQKSSFDIVMQGFDTGNVIPFL
DQYDYKEQLEAYRIYYDQLVCNFKLSAPDKIPLSAEKLNAIIHWYAHDALIHFASPHGLEQSGGAAWGTRDVCQGPIEFF
LTTGHFDLVRHILITLYSHQIEGGFEWPQWFMFDHYPIHQEDCHGDVVFWPLKAISDYIQATGDTSILNELVDYRTAKDA
LPTNQPETILIHIKRAVTTIKNRYLSGTALISYAGGDWDDTLQPANSELKENLVSAWTQALAEQTLELLCSAIKGIDHDF
SKELSHMANDIRTSFYQYLIKDGVIAGFLYRESEEHMKYMLHPDDTESSIHYRLLPLTRSIIAQLADFKLATRNLEIIDE
HLACPDGVRLMDHPASYSGGISKIFLRAEQAANVGREISLQYVHAHIRYIEALATMGLSKKAWDALMRINPILLTDYVPN
ALTRQSNVYFSSSEGCFDDRYEYAKNFDKLRTGDINVKGGWRLYSSGPGIYIRRIIADLLGIRFGHNVIHIDPVVTKELD
GVTLQFTCFGKTVFFTYHVDDTMDKHICVKSNNNILPGDNLNNIYRDGGIQIAKDVFLSAAMSDNNFHIYVKN

The query sequence (length=1113) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5h3z:B 1113 1113 1.0000 1.0000 1.0000 0.0 5h40:A, 5h40:B, 5h41:A, 5h41:B, 5h42:A, 5h42:B
2 8rf0:A 2780 517 0.1105 0.0442 0.2379 7.34e-11 8rfe:A, 8rfg:A
3 1v7v:A 779 509 0.0889 0.1271 0.1945 1.04e-10 1v7w:A, 1v7x:A
4 3qde:A 811 548 0.1069 0.1467 0.2172 1.99e-06 8ho8:A, 8ho8:B, 3qde:B
5 4zlf:A 785 285 0.0602 0.0854 0.2351 2.61e-05 4zlg:A, 4zli:A
6 8h2w:B 984 470 0.0827 0.0935 0.1957 0.003 8h2w:A, 5nz8:B
7 3acs:A 822 210 0.0467 0.0633 0.2476 0.041 3acs:B, 3act:A, 3act:B, 3afj:A, 3afj:B, 2cqs:A, 2cqs:B, 2cqt:A, 2cqt:B, 3qfy:A, 3qfy:B, 3qfz:A, 3qfz:B, 3qg0:A, 3qg0:B
8 3s4a:A 822 224 0.0494 0.0669 0.2455 0.061 3s4a:B, 3s4b:A, 3s4b:B, 3s4d:A
9 7l1k:B 660 55 0.0144 0.0242 0.2909 0.54
10 5e6m:A 519 71 0.0171 0.0366 0.2676 0.56 4kr2:A, 4kr3:A
11 3zok:A 365 94 0.0234 0.0712 0.2766 1.4 3zok:B, 3zok:C, 3zok:D
12 7r39:A 412 67 0.0162 0.0437 0.2687 2.9 7r39:B, 7r39:C, 7r39:D, 7r39:E, 7r39:F, 7r39:G, 7r39:H
13 5e6m:B 506 57 0.0153 0.0336 0.2982 3.0
14 2zt5:A 530 135 0.0288 0.0604 0.2370 3.1 2zt6:A, 2zt7:A, 2zt8:A, 2zxf:A
15 4qei:A 562 57 0.0153 0.0302 0.2982 3.2
16 8r3r:A 658 113 0.0261 0.0441 0.2566 3.5 8r3r:B, 8r3r:C, 8r3r:D
17 3ujm:A 117 49 0.0135 0.1282 0.3061 4.0 3ujm:B
18 5nz8:A 884 95 0.0234 0.0294 0.2737 6.2
19 3dr2:A 299 52 0.0162 0.0602 0.3462 7.0 3dr2:B
20 6am5:E 242 99 0.0288 0.1322 0.3232 8.7 6amu:E, 6d78:E, 6dkp:E, 4l3e:E, 3qdg:E, 3qdj:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218