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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GDTSYAKNSAYNQLVLAKVKPVLEQCVRELLRANLPNINKCIKVADLGCASGPNTLLTVRDIVQSIDKVGQLERPTIQIF
LNDLFPNDFNSVFKLLPSFYRKLEKENGRKIGSCLIGAMPGSFYSRLFPEESMHFLHSCYCLQWLSQVPSGLVTELIGTN
KGSIYSSKASRLPVQKAYLDQFTKDFTTFLRIHSEELFSHGRMLLTCICKGVELDARNAIDLLEMAINDLVVEGHLEEEK
LDSFNLPVYIPSAEEVKCIVEEEGSFEILYLETFKVLYDAGFSHIKAEYVASSVRAVYEPILASHFGEAIIPDIFHRFAK
HAAKVLPLGKGFYNNLIISLAKKP

The query sequence (length=344) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2eg5:E 346 346 1.0000 0.9942 0.9942 0.0 2eg5:A, 2eg5:C, 2eg5:G
2 2efj:A 348 350 0.8023 0.7931 0.7886 0.0
3 1m6e:X 359 359 0.4215 0.4039 0.4039 9.75e-80
4 6lyh:A 358 332 0.3808 0.3659 0.3946 1.65e-69 6lyh:B, 6lyh:C, 6lyh:D, 6lyh:E, 6lyh:F, 6lyh:G, 6lyh:H
5 8t2g:A 333 332 0.3605 0.3724 0.3735 1.11e-65 8t2g:B, 8uzd:A, 8uzd:B
6 6c8r:A 358 331 0.3285 0.3156 0.3414 1.20e-49 6c8r:B, 6c8s:A, 6c8s:B
7 3b5i:A 344 300 0.3023 0.3023 0.3467 1.33e-45 3b5i:B
8 5f2k:A 358 277 0.2093 0.2011 0.2599 1.08e-16 5f2k:B, 5f2n:A, 5f2n:B, 5f2o:A, 5f2o:B
9 2imc:B 405 84 0.0814 0.0691 0.3333 0.34 3dse:A, 4hev:A, 4hev:B, 2ima:A, 2ima:B, 2imb:A, 2imb:B, 2imc:A, 7ky2:A, 7ky2:B, 7kyh:A, 7kyh:B, 7kyh:C, 7kyh:D, 7n18:A, 7n18:B, 3nf3:A, 3qix:A, 3qix:B, 3qiy:A, 3qiz:A, 3qj0:A, 5v8p:A, 5v8p:B, 5v8r:A, 5v8r:B, 5v8u:A, 5v8u:B
10 3v0a:A 1280 84 0.0814 0.0219 0.3333 0.60 8agk:AAA, 3bon:A, 3boo:A, 3bta:A, 3bwi:A, 3c88:A, 3c89:A, 3c8a:A, 3c8b:A, 3dda:A, 3ddb:A, 3ds9:A, 1e1h:A, 1e1h:C, 4ej5:A, 4el4:A, 4elc:A, 2g7n:A, 2g7p:A, 2g7p:B, 2g7q:A, 2g7q:B, 8hkh:A, 8hkh:B, 2ilp:A, 2ilp:B, 2ise:A, 2ise:B, 2isg:A, 2isg:B, 2ish:A, 2ish:B, 3k3q:B, 4ks6:A, 4ktx:A, 4kuf:A, 7kyf:C, 7l6v:A, 7lzp:A, 7lzp:D, 7m1h:A, 2nyy:A, 2nz9:A, 2nz9:B, 7qpt:A, 7qpu:A, 3qw5:A, 3qw6:A, 3qw7:A, 3qw8:A, 5tpb:B, 5tpc:A, 3v0b:A, 3v0c:A, 5vgv:A, 2vu9:A, 2w2d:A, 2w2d:C, 6xcb:A, 6xcc:A, 6xcd:A, 6xce:A, 6xcf:A, 1xtf:A, 1xtf:B, 1xtg:A, 4zjx:A, 3zus:A, 3zus:B, 3zus:C, 3zus:D
11 8ipr:A 504 40 0.0349 0.0238 0.3000 4.3 8ipr:D
12 9b8t:A 1146 53 0.0436 0.0131 0.2830 4.4 9b8s:A, 9f6d:A, 9f6e:A, 9f6f:A, 9f6i:A, 9f6j:A, 9f6k:A, 9f6l:A
13 7ehq:A 406 40 0.0552 0.0468 0.4750 5.9 7ehu:A
14 7v9a:D 117 51 0.0407 0.1197 0.2745 8.5
15 1p9b:A 424 92 0.0756 0.0613 0.2826 8.9
16 7zbh:B 374 92 0.0727 0.0668 0.2717 9.9 7zbh:A, 7zbh:D, 7zbh:F, 7zbh:I, 7zbh:K

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218