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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GARRAAAAAAAAGAFAGRRAACGAVLLTELLERAAFYGITSNLVLFLNGAPFCWEGAQASEALLLFMGLTYLGSPFGGWL
ADARLGRARAILLSLALYLLGMLAFPLLAAPATRAALCGSARLLNCTAPGPDAAARCCSPATFAGLVLVGLGVATVKANI
TPFGADQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFVTGYAIPTVCVGLAFVVFLCGQSVFITKPPDGS
AFTDMFKILTYSCCSQKRFDSCKMSHGGPFTEEKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYVLQSLHLRIPEISNI
TTTPHTLPAAWLTMFDAVLILLLIPLKDKLVDPILRRHGLLPSSLKRIAVGMFFVMCSAFAAGILESKRLNLVKEKTINQ
TIGNVVYHAADLSLWWQVPQYLLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGVGSFVGSGLLALVSIKAIGW
MSSHTDFGNINGCYLNYYFFLLAAIQGATLLLFLIISVKYDHH

The query sequence (length=523) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8qsk:A 523 523 1.0000 1.0000 1.0000 0.0 8qsk:C, 8qsl:A, 8qsl:C, 8wx5:A
2 8jzs:B 486 519 0.9293 1.0000 0.9364 0.0 8jzs:A, 8jzu:A, 8wx4:B, 8wx4:A
3 8jzx:A 455 519 0.8700 1.0000 0.8767 0.0 8jzx:B
4 9bis:A 472 460 0.2294 0.2542 0.2609 3.16e-40 9bir:A, 9bit:A, 9biu:A
5 5a2o:A 470 515 0.2620 0.2915 0.2660 3.23e-35
6 4uvm:A 505 509 0.2218 0.2297 0.2279 3.05e-28
7 6ei3:A 511 495 0.2180 0.2231 0.2303 9.54e-27
8 7pmy:A 657 371 0.1702 0.1355 0.2399 8.52e-26
9 7pmy:A 657 57 0.0440 0.0350 0.4035 7.29e-07
10 7pmx:A 657 399 0.1721 0.1370 0.2256 1.15e-24 7pmw:A
11 7pmx:A 657 57 0.0382 0.0304 0.3509 1.50e-04 7pmw:A
12 4ikz:A 485 494 0.2084 0.2247 0.2206 1.54e-09
13 6fmr:A 475 500 0.1950 0.2147 0.2040 9.65e-08 4d2b:A, 4d2d:A, 5d58:A, 5d59:A, 6eia:A, 6fmy:A, 6ghj:A, 5oxl:A, 5oxm:A, 5oxn:A, 5oxo:A, 5oxq:A, 4xnj:A, 6yof:A, 6yog:A
14 7q0m:A 482 494 0.2161 0.2344 0.2287 7.93e-06
15 5oxp:A 462 494 0.1912 0.2165 0.2024 8.32e-05 7ac6:A, 4d2c:A, 5d6k:A, 5oxk:A, 4xni:A
16 6gz9:A 488 222 0.0994 0.1066 0.2342 0.003 6exs:A, 6hzp:A
17 4tpg:A 459 202 0.0860 0.0980 0.2228 0.077 4lep:A, 4lep:B, 4tph:A, 4tpj:B, 4tpj:A
18 6gs4:A 468 200 0.0803 0.0897 0.2100 0.77
19 3a79:A 550 72 0.0363 0.0345 0.2639 1.8 3a7b:A, 3a7c:A, 2z81:A, 2z82:A
20 8b17:A 451 172 0.0841 0.0976 0.2558 1.9 8b18:A, 8b19:A, 8b1a:A, 8b1b:A, 8b1c:A, 8b1d:A, 8b1e:A, 8b1f:A, 8b1g:A, 8b1h:A, 8b1i:A, 8b1j:A, 8b1k:A
21 3wir:A 756 34 0.0268 0.0185 0.4118 2.0 3wiq:A, 3wir:B, 3wir:C, 3wir:D
22 5dcy:A 366 38 0.0249 0.0355 0.3421 4.1 5cob:A, 5cob:B, 5cob:C, 5cob:D, 5dbf:A, 5dbf:B, 5dbg:A, 5dbg:B, 5dbi:A, 5dbi:B, 5dcu:A, 5dcu:B, 5dcy:B, 5df1:A, 5df1:B, 5emh:A
23 7am2:CA 537 34 0.0210 0.0205 0.3235 7.2
24 5i78:A 305 22 0.0210 0.0361 0.5000 8.6 5i79:A, 5i79:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218