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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EVLALLSRVEAKGKGILQQNQIIAEFEALPEQTRKKLEGGPFFDLLKSTQEAIVLPPWVALAVRPRPGVWEYLRVNLHAL
VVEELQPAEFLHFKEELVDGVKNGNFTLELDFEPFNASIPRPTLHKYIGNGVDFLNRHLSAKLFHDKESLLPLLKFLRLH
SHQGKNLMLSEKIQNLNTLQHTLRKAEEYLAELKSETLYEEFEAKFEEIGLERGWGDNAERVLDMIRLLLDLLEAPDPCT
LETFLGRVPMVFNVVILSPHGYFAQDNVLGYPDTGGQVVYILDQVRALEIEMLQRIKQQGLNIKPRILILTRLLPDAVGT
TCGERLERVYDSEYCDILRVPFRTEKGIVRKWISRFEVWPYLETYTEDAAVELSKELNGKPDLIIGNYSDGNLVASLLAH
KLGVTQCTIAHALEKTKYPDSDIYWKKLDDKYHFSCQFTADIFAMNHTDFIITSTFQEIAGSKETVGQYESHTAFTLPGL
YRVVHGIDVFDPKFNIVSPGADMSIYFPYTEEKRRLTKFHSEIEELLYSDVENKEHLCVLKDKKKPILFTMARLDRVKNL
SGLVEWYGKNTRLRELANLVVVGGDRRKESKDNEEKAEMKKMYDLIEEYKLNGQFRWISSQMDRVRNGELYRYICDTKGA
FVQPALYEAFGLTVVEAMTCGLPTFATCKGGPAEIIVHGKSGFHIDPYHGDQAADTLADFFTKCKEDPSHWDEISKGGLQ
RIEEKYTWQIYSQRLLTLTGVYGFWKHVSNLDRLEARRYLEMFYALKYRPLAQAVPLAQD

The query sequence (length=780) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3s27:H 797 780 1.0000 0.9787 1.0000 0.0 3s27:A, 3s27:B, 3s27:C, 3s27:D, 3s27:E, 3s27:F, 3s27:G, 3s28:A, 3s28:B, 3s28:C, 3s28:D, 3s28:E, 3s28:F, 3s28:G, 3s28:H, 3s29:A, 3s29:B, 3s29:C, 3s29:D, 3s29:E, 3s29:F, 3s29:G, 3s29:H
2 2r66:A 456 487 0.1769 0.3026 0.2834 4.20e-44 2r68:A
3 6kih:A 400 205 0.0692 0.1350 0.2634 4.35e-15 6kih:C, 6kih:D, 6kih:E, 6kih:F, 6kih:H, 6kih:I, 6kih:K, 6kih:L, 6kih:B, 6kih:G, 6kih:J
4 5d00:A 361 270 0.0962 0.2078 0.2778 7.91e-11 5d00:B, 5d01:A, 5d01:B
5 5zer:A 354 63 0.0359 0.0791 0.4444 1.26e-09 5zer:B, 5zes:A, 5zfk:A, 5zfk:B
6 6n1x:A 377 97 0.0397 0.0822 0.3196 2.08e-07 6d9t:A
7 3oka:A 378 247 0.0628 0.1296 0.1984 1.59e-06 3oka:B, 3okc:A, 3okp:A
8 4xsu:A 368 184 0.0538 0.1141 0.2283 5.47e-06 4xsp:A, 4xsr:B, 4xsr:A, 4xsu:B
9 3mbo:E 375 36 0.0231 0.0480 0.5000 5.99e-05 3mbo:A, 3mbo:C, 3mbo:H
10 7fga:B 344 36 0.0231 0.0523 0.5000 1.44e-04 7fg9:A, 7fg9:B, 7fga:D, 7fga:A, 7fga:C
11 3c4q:A 393 58 0.0244 0.0483 0.3276 0.012 3c4q:B, 3c4v:A, 3c4v:B
12 6zn1:AAA 400 151 0.0462 0.0900 0.2384 0.014 6zjh:AAA, 6zmz:AAA
13 3vuf:A 488 144 0.0423 0.0676 0.2292 0.020
14 4wad:A 498 77 0.0295 0.0462 0.2987 0.021 4x6l:A, 4x6l:B, 4x6l:C, 4x7m:A, 4x7m:B, 4x7r:A, 4x7r:B
15 2xa2:A 412 144 0.0500 0.0947 0.2708 0.025 2xa2:B, 2xa9:A, 2xa9:B, 2xmp:A, 2xmp:B
16 8p1x:AAA 492 90 0.0295 0.0467 0.2556 0.067 8p20:AAA, 8p20:BBB, 8p20:CCC, 8p20:DDD, 7qd7:AAA, 7qh9:AAA, 7qh9:BBB, 7qh9:CCC, 7qh9:DDD
17 2iv7:A 370 64 0.0269 0.0568 0.3281 0.067 2iw1:A
18 7w41:A 484 217 0.0615 0.0992 0.2212 0.17
19 2bis:A 440 220 0.0577 0.1023 0.2045 0.25 2bis:C, 3fro:B, 3l01:A, 3l01:B
20 5n80:A 358 44 0.0192 0.0419 0.3409 0.36 6y6i:A
21 6lfl:A 471 105 0.0321 0.0531 0.2381 0.65
22 3gma:B 566 36 0.0192 0.0265 0.4167 1.1 3gf3:A, 3glm:A, 3glm:C, 3glm:B, 3glm:D, 3gma:A
23 6me2:A 486 105 0.0333 0.0535 0.2476 1.1 6me3:A, 6me4:A, 6me5:A, 6ps8:A
24 2gej:A 361 130 0.0410 0.0886 0.2462 1.2 2gek:A, 4n9w:A
25 4pkb:A 357 70 0.0244 0.0532 0.2714 1.2
26 7br3:A 470 145 0.0397 0.0660 0.2138 1.2
27 7fee:A 486 105 0.0321 0.0514 0.2381 1.4 6kqi:A, 5u09:A
28 6w25:A 468 172 0.0500 0.0833 0.2267 1.4 8wky:A, 8wkz:A
29 6v9s:A 503 105 0.0333 0.0517 0.2476 1.5 4zj8:A, 4zjc:A
30 6hlp:A 485 181 0.0513 0.0825 0.2210 1.7 6e59:A, 6hll:A, 6hlo:A
31 6jix:A 447 116 0.0410 0.0716 0.2759 2.2 6jix:B, 6jix:D, 6jix:C
32 6tpk:A 461 105 0.0333 0.0564 0.2476 2.3 7qvm:R
33 6fj3:A 562 105 0.0321 0.0445 0.2381 2.4 8d51:A, 8d52:A, 7uzo:A, 7uzp:A, 7uzp:C, 7uzp:E
34 8gz2:B 1174 74 0.0244 0.0162 0.2568 2.7 8gz1:B
35 6tpn:A 510 105 0.0333 0.0510 0.2476 2.9 4s0v:A, 6tpg:A, 6tpj:A, 6tpj:B, 5wqc:A, 5ws3:A
36 8fhd:A 1294 75 0.0244 0.0147 0.2533 3.0
37 8fhd:A 1294 40 0.0218 0.0131 0.4250 8.0
38 8b5q:B 365 79 0.0295 0.0630 0.2911 3.1 8b5q:A, 8b5s:A, 8b5s:B, 8b62:A, 8b62:B, 8b63:A, 8b63:B
39 6kuw:A 474 105 0.0333 0.0549 0.2476 3.1 6kuw:B
40 4die:C 213 55 0.0205 0.0751 0.2909 3.9 4die:A, 4die:B, 4die:D
41 8cxo:A 551 105 0.0321 0.0454 0.2381 4.5
42 5e9u:A 503 44 0.0192 0.0298 0.3409 5.3 5e9u:E
43 5xyi:E 246 122 0.0397 0.1260 0.2541 5.6
44 5jrz:A 443 95 0.0359 0.0632 0.2947 5.9 6adx:A, 6ady:A, 7g9k:A, 7g9l:A, 7g9m:A, 7g9o:A, 7g9p:A, 7g9q:A, 7g9r:A, 7g9s:A, 7g9t:A, 7g9u:A, 7g9v:A, 7g9w:A, 7g9x:A, 7g9y:A, 7ga0:A, 7ga1:A, 7ga2:A, 7ga3:A, 7ga5:A, 7ga6:A, 7ga7:A, 5gjb:A, 5gjc:A, 5k8i:A, 5k8l:A, 5k8t:A, 5k8u:A, 5mfx:A, 5rhg:A, 5rhi:A, 5rhj:A, 5rhk:A, 5rhl:A, 5rhm:A, 5rho:A, 5rhp:A, 5rhq:A, 5rhr:A, 5rhs:A, 5rht:A, 5rhu:A, 5rhv:A, 5rhw:A, 5rhx:A, 6rwz:A, 6s0j:A, 8um3:A, 7v2z:A, 8v7r:A, 8v7u:A, 5y4z:A, 5y6m:A, 5y6n:A
45 5loe:A 258 53 0.0244 0.0736 0.3585 6.4 2b18:A, 2gx5:C, 2hgv:A, 5loe:B, 5loe:C, 5loe:D
46 8h0l:A 152 35 0.0154 0.0789 0.3429 6.7 8h0l:B
47 5fp1:A 701 48 0.0167 0.0185 0.2708 8.4
48 8c7s:A 256 53 0.0231 0.0703 0.3396 8.5 8c7s:B, 5ey0:B, 5ey0:A, 5ey1:A, 5ey1:B
49 5t25:A 293 61 0.0231 0.0614 0.2951 8.6 2ats:A, 2ats:B, 3i7s:A, 3i7s:B, 7jz8:A, 7jz8:B, 7jza:A, 7jza:B, 7jzb:A, 7jzb:B, 7jzg:A, 7jzg:B, 5t25:B, 1yxd:A, 1yxd:B
50 6vld:B 469 51 0.0179 0.0299 0.2745 9.6 6tkv:A, 6tkv:B, 6vld:A, 6vlg:A, 6vlg:B, 6vlg:C, 6vlg:D, 6x5h:A, 6x5h:B, 6x5h:C, 6x5r:B, 6x5r:A, 6x5s:A, 6x5s:B, 6x5t:A, 6x5t:B, 6x5t:C, 6x5t:D, 6x5t:E, 6x5t:F, 6x5t:G, 6x5t:H, 6x5u:E, 6x5u:B, 6x5u:D, 6x5u:F, 6x5u:A, 6x5u:G, 6x5u:C, 6x5u:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218