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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ESILHSEIGRLNNQSLLWGPYRPNIYFGTRPRIGKSLMTGLMWGKIESYTDFQHTVRYTCEQNEGMKGYGWDEYDPRRGG
IQSIHDIQNGLDITTSFVKIPGGAHGGSWAARIKGTLNDDAPKDQKTIVVFYVSQEGENSELEAVPSENEFGYEGDVILK
GRSEALGNYKLVVTKGKGVIPQSDHDLSRLRGPGQTVVQSLTYPDEVLWQAKPILFQQLKAGIDWLVENKYDVADPPPPW
QVYLLANKPGSGNVHIVQKVFEGDFEFDILFSSESAGKEVTSKDLEREVKQATEVFGERFARVFDLKAPFQGDNYKKFGK
SMFSNLIGGIGYFYGHSLVDRSYAPEYDEENEGFWEDAAEARARHQEALEGPYELFTSIPSRPFFPRGFLWDEGFHLLPI
ADWDIDLALEIIKSWYNLMDEDGWIAREQILGAEARSKVPKEFQTQYPHYANPPTLFLVLDNFVERLRKNNATLSTASVD
NPEVGLEYLRRLYPLLRRQFDWFRKTQAGDIKSYDREAYSTKEAYRWRGRTVSHCLTSGLDDYPRPQPPHPGELHVDLMS
WVGVMVKSLISIGSLLGATEDVEFYTKVLDAIEHNLDDLHWSEKEGCYCDATIDEFEEHKLVCHKGYISLFPFLTGLLKP
DSPKLGKLLALIGDESELWSPYGLRSLSKKDEFYGTAENYWRSPVWININYLAIVQLYNIATQDGPYKETARDLYTRLRK
NIVETVYRNWEETGFAWEQYNPETGKGQRTQHFTGWTSLVVKIMSGH

The query sequence (length=767) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8e4i:B 769 769 1.0000 0.9974 0.9974 0.0 8e3j:A, 8e3j:B, 8e3p:A, 8e3p:B, 8e4i:A, 8e4k:A, 8e4k:B, 8e4z:A, 8e4z:B, 8e5u:A, 8e5u:B, 8e6g:A, 8e6g:B, 8ecw:A, 8ecw:B, 8egv:A, 8egv:B, 8ehp:A, 8ehp:B, 8eid:A, 8eid:B, 8ekn:A, 8ekn:B, 8ele:A, 8ele:B, 8epj:A, 8epj:B, 8epo:A, 8epo:B, 8epr:A, 8epr:B, 8eq7:A, 8eq7:B, 8eqx:A, 8eqx:B, 8er4:A, 8er4:B, 8etl:A, 8etl:B, 8eto:A, 8eto:B, 8eud:A, 8eud:B, 8eur:A, 8eur:B, 8eut:A, 8eut:B, 8eux:A, 8eux:B, 7r6j:A, 7r6j:B, 7rd2:A, 7rd2:B, 7rev:A, 7rev:B, 7t66:A, 7t66:B, 7t68:A, 7t68:B, 7t8v:A, 7t8v:B
2 5mhf:D 767 810 0.3690 0.3690 0.3494 3.52e-132 5mhf:A, 5mhf:B, 5mhf:C
3 4wvb:A 394 166 0.0548 0.1066 0.2530 8.86e-04
4 4wvc:A 413 166 0.0548 0.1017 0.2530 0.001 4wvc:B
5 2jg0:A 507 173 0.0522 0.0789 0.2312 0.14 2jf4:A, 2jjb:A, 2jjb:B, 2jjb:C, 2jjb:D, 2wyn:A, 2wyn:B, 2wyn:C, 2wyn:D
6 8f5b:A 1924 96 0.0352 0.0140 0.2812 0.60 7lkz:A
7 1fcd:A 401 71 0.0339 0.0648 0.3662 3.0 1fcd:B
8 3fcc:A 500 62 0.0261 0.0400 0.3226 5.0 3dhv:A, 3fce:A
9 3m6w:A 460 182 0.0652 0.1087 0.2747 6.1 3m6v:A, 3m6v:B
10 3e2v:A 363 81 0.0326 0.0689 0.3086 8.3 3e2v:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218