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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EPLSYLGKDGGPWEIFTEQVDRVVPYLGRLAPLAESLKRPKRVLIVDVPVRLDDGSVAYFEGYRVHHNTARGPAKGGVRY
HPEVTLSEVMALAGWMTIKNAAVGLPYGGGKGGIRVDPRKLSPGELERLTRRYTSEIGILLGPDRDIPAPDVNTGEREMA
WMMDTYSMNVGRTVPGVVTGKPIALGGSLGRRDATGRGVFITAAAAAEKIGLQVEGARVAIQGFGNVGNAAARAFHDHGA
RVVAVQDHTGTVYNEAGIDPYDLLRHVQEFGGVRGYPKAEPLPAADFWGLPVEFLVPAALEKQITEQNARIVAEGANGPT
TPAADDILLEKGVLVVPDVIANAGGVTVSYFEWVQDFNSYFWTEEEINARLERVLRNAFEAVWQVAQEKKIPLRTAAYVV
AATRVLEARALRGLYP

The query sequence (length=416) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3aoe:B 424 421 1.0000 0.9811 0.9881 0.0 3aoe:A, 3aog:A, 3aog:E, 3aog:B, 3aog:D, 3aog:C, 3aog:F, 3aog:G, 3aog:I, 3aog:H, 3aog:J, 3aog:L, 3aog:K
2 4xgi:A 416 419 0.6731 0.6731 0.6683 0.0 4xgi:B, 4xgi:C, 4xgi:D, 4xgi:E, 4xgi:F
3 8xd5:A 419 410 0.4880 0.4845 0.4951 2.89e-133 8hho:A, 8hiq:A, 8hiz:A, 8hj9:A, 8xco:A, 8xcp:A, 8xcq:A, 8xcr:A, 8xcs:A, 8xct:A, 8xcu:A, 8xcv:A, 8xcw:A, 8xcx:A, 8xcy:A, 8xcz:A, 8xd0:A, 8xd1:A, 8xd2:A, 8xd3:A, 8xd4:A, 8xd6:A, 8znb:A, 8znc:A, 8znd:A, 8zne:A, 8zng:A
4 6yeh:A 410 392 0.4447 0.4512 0.4719 6.39e-118 6yeh:B, 6yeh:C, 6yeh:D, 6yeh:E, 6yeh:F, 6yei:A, 6yei:B, 6yei:C, 6yei:D, 6yei:E, 6yei:F
5 8s38:B 414 397 0.4303 0.4324 0.4509 3.44e-112 8s38:A, 8s38:C, 8s39:A, 8s39:B, 8s39:C, 8s3a:A, 8s3a:B, 8s3a:C, 8s3a:D, 8s3a:E, 8s3a:F, 8s3b:A, 8s3b:B, 8s3b:C, 8s3b:D, 8s3b:E, 8s3b:F, 8s3b:G, 8s3b:H, 8s3b:I, 8s3b:J, 8s3b:K, 8s3b:L, 8s3c:B, 8s3d:A, 8s3d:B, 8s3d:C, 8s3d:D, 8s3d:E, 8s3d:F
6 8owm:C 413 392 0.4183 0.4213 0.4439 9.97e-112 8owm:A, 8owm:B, 8owm:D, 8owm:E, 8owm:F, 8own:A, 8own:B, 8own:C, 8own:D, 8own:E, 8own:F
7 3aoe:F 417 414 0.4615 0.4604 0.4638 9.96e-110 3aoe:E, 3aoe:C, 3aoe:D
8 1v9l:A 418 393 0.4543 0.4522 0.4809 7.55e-109 1v9l:B, 1v9l:C, 1v9l:D, 1v9l:E, 1v9l:F
9 8kar:A 414 400 0.4159 0.4179 0.4325 9.84e-99 8kao:C, 8kar:B, 8kar:C
10 6dhd:A 501 376 0.3870 0.3214 0.4282 8.85e-95 8ar7:A, 8ar7:B, 8ar7:C, 8ar7:E, 8ar7:D, 8ar7:F, 8ar8:A, 8ar8:B, 8ar8:C, 8ar8:D, 8ar8:E, 8ar8:F, 6dhd:B, 6dhd:C, 6dhd:D, 6dhd:F, 6dhd:E, 6dhk:A, 6dhk:B, 6dhk:F, 6dhk:C, 6dhk:D, 6dhk:E, 6dhk:G, 6dhk:H, 6dhk:L, 6dhk:I, 6dhk:J, 6dhk:K, 6dhl:A, 6dhl:F, 6dhl:B, 6dhl:C, 6dhl:D, 6dhl:E, 6dhl:G, 6dhl:L, 6dhl:H, 6dhl:I, 6dhl:J, 6dhl:K, 6dhm:A, 6dhm:B, 6dhm:C, 6dhm:D, 6dhm:E, 6dhm:F, 6dhn:A, 6dhn:B, 6dhn:C, 6dhn:D, 6dhn:E, 6dhn:F, 6dhq:A, 6dhq:B, 6dhq:C, 6dhq:D, 6dhq:E, 6dhq:F, 3etd:A, 3etd:E, 3etd:B, 3etd:C, 3etd:D, 3etd:F, 3ete:A, 3ete:E, 3ete:B, 3ete:C, 3ete:F, 3ete:D, 3etg:A, 3etg:B, 3etg:C, 3etg:D, 3etg:E, 3etg:F, 1hwy:A, 1hwy:B, 1hwy:F, 1hwy:C, 1hwy:E, 1hwy:D, 3jd0:A, 3jd0:B, 3jd0:C, 3jd0:D, 3jd0:E, 3jd0:F, 3jd1:A, 3jd1:C, 3jd1:B, 3jd1:D, 3jd1:F, 3jd1:E, 3jd2:A, 3jd2:B, 3jd2:C, 3jd2:D, 3jd2:E, 3jd2:F, 3jd3:A, 3jd3:B, 3jd3:C, 3jd3:D, 3jd3:E, 3jd3:F, 3jd4:A, 3jd4:C, 3jd4:B, 3jd4:D, 3jd4:F, 3jd4:E, 1nqt:A, 1nqt:B, 1nqt:F, 1nqt:C, 1nqt:D, 1nqt:E, 1nqt:G, 1nqt:H, 1nqt:L, 1nqt:I, 1nqt:J, 1nqt:K
11 1bgv:A 449 433 0.3317 0.3073 0.3187 2.99e-56
12 5gud:E 460 370 0.3029 0.2739 0.3405 7.39e-56 5gud:A, 5gud:B, 5gud:C, 5gud:D, 5gud:F, 5ijz:A, 5ijz:B, 5ijz:C, 5ijz:D, 5ijz:E, 5ijz:F, 5ijz:G, 5ijz:H, 5ijz:J
13 7f79:C 458 420 0.3101 0.2817 0.3071 3.38e-45 7f79:A, 7f79:B, 7f79:D, 7f79:E, 7f79:F
14 5xvv:B 459 416 0.3197 0.2898 0.3197 4.36e-41 5xvv:A, 5xvv:C, 5xvx:A, 5xw0:A, 5xwc:A
15 7ecr:A 460 416 0.3245 0.2935 0.3245 5.01e-41 7ecr:B, 7ecr:C, 7ecs:A, 7ecs:B, 7ecs:C, 7ect:A, 7ect:B, 7ect:C
16 6ach:A 364 363 0.2692 0.3077 0.3085 5.74e-26 6ach:B, 6ach:C, 6ach:D, 6ach:E, 6ach:F, 6ach:G, 6ach:H
17 8gxd:A 366 353 0.2548 0.2896 0.3003 4.82e-22
18 8hr6:A 359 361 0.2380 0.2758 0.2742 6.69e-21 8hr6:B
19 1bw9:A 350 354 0.2380 0.2829 0.2797 1.17e-17 1bw9:B, 1bxg:A, 1bxg:B, 1c1d:A, 1c1d:B, 1c1x:A, 1c1x:B
20 6itd:A 328 64 0.0553 0.0701 0.3594 0.10 6k36:A, 6k37:A, 6k38:A
21 6bul:B 327 125 0.0841 0.1070 0.2800 0.19 6aqj:A, 6aqj:B, 6bul:A, 6c55:A, 6c55:B, 6c5n:A, 6c5n:B, 7ke2:B, 7ke2:A, 7kh7:A, 7kh7:B, 6vo2:A, 6vo2:B, 5w3k:A, 5w3k:B
22 2x0i:A 294 40 0.0457 0.0646 0.4750 0.34 2x0j:A
23 5vmt:B 334 59 0.0481 0.0599 0.3390 0.45 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
24 3gnq:C 335 49 0.0433 0.0537 0.3673 0.67 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
25 1dss:G 333 31 0.0337 0.0420 0.4516 1.3 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
26 5v96:A 467 54 0.0409 0.0364 0.3148 1.4 5v96:B, 5v96:C, 5v96:D
27 2vyn:D 334 30 0.0337 0.0419 0.4667 1.4 2vyv:D
28 7quj:A 259 37 0.0433 0.0695 0.4865 1.6 7quj:B, 7quj:C, 7quj:D
29 1ay0:A 678 64 0.0505 0.0310 0.3281 1.6 1ay0:B, 1gpu:A, 1gpu:B, 1ngs:A, 1ngs:B, 1tka:A, 1tka:B, 1tkb:A, 1tkb:B, 1tkc:A, 1tkc:B, 1trk:A, 1trk:B
30 3ce6:A 486 54 0.0433 0.0370 0.3333 2.3 3ce6:B, 3ce6:C, 3ce6:D, 3dhy:A, 3dhy:B, 3dhy:C, 3dhy:D, 2ziz:A, 2ziz:B, 2ziz:C, 2ziz:D, 2zj0:A, 2zj0:B, 2zj0:C, 2zj0:D, 2zj1:A, 2zj1:B, 2zj1:C, 2zj1:D
31 3h9e:P 337 29 0.0337 0.0415 0.4828 2.5 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
32 3lvf:P 338 59 0.0481 0.0592 0.3390 2.6 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
33 6zyz:A 259 42 0.0457 0.0734 0.4524 2.7 6zyz:B, 6zyz:C, 6zyz:D, 6zzt:C
34 5ld5:C 342 33 0.0361 0.0439 0.4545 2.8 5ld5:A, 5ld5:B, 5ld5:D
35 4i58:A 451 28 0.0361 0.0333 0.5357 2.9 4i58:B, 4i58:C, 4i58:D, 4i59:A, 4i59:B, 4i59:C, 4i59:D
36 7etx:A 472 23 0.0288 0.0254 0.5217 4.2 7ety:A, 7ety:B
37 8k32:C 333 30 0.0288 0.0360 0.4000 4.4 8k32:A, 8k32:B, 8k32:D
38 1uod:A 336 51 0.0409 0.0506 0.3333 4.9 3pnq:D, 1uod:B, 1uoe:A, 1uoe:B
39 6zja:B 569 69 0.0505 0.0369 0.3043 5.2 6zja:J, 6zja:D, 6zja:F, 6zja:H, 6zja:L, 6zja:N, 6zja:P, 6zja:R, 6zja:T, 6zja:V, 6zja:X
40 4aut:A 419 55 0.0385 0.0382 0.2909 6.2 4f4q:A
41 1hdg:O 332 100 0.0721 0.0904 0.3000 6.4 1hdg:Q
42 2ekl:A 312 75 0.0505 0.0673 0.2800 6.6
43 3pvs:D 424 65 0.0505 0.0495 0.3231 7.3 3pvs:A, 3pvs:B
44 6j61:A 242 145 0.1058 0.1818 0.3034 7.5 6j61:B, 6j61:D, 6j61:C
45 3d3w:A 244 54 0.0505 0.0861 0.3889 7.9 3d3w:B, 1pr9:A, 1pr9:B, 1wnt:A, 1wnt:B, 1wnt:C, 1wnt:D
46 6xn1:B 333 51 0.0457 0.0571 0.3725 8.6 6xn1:A, 6xn2:B, 6xn2:A
47 1dxy:A 330 117 0.0673 0.0848 0.2393 8.6
48 3k2b:A 337 48 0.0409 0.0504 0.3542 8.8 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
49 3g1u:C 424 35 0.0288 0.0283 0.3429 9.0 3g1u:A, 3g1u:B, 3g1u:D
50 5yeq:B 329 52 0.0385 0.0486 0.3077 9.1
51 6jx2:B 327 30 0.0288 0.0367 0.4000 9.2 6jx2:A, 6jx2:C, 6jx2:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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