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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EMTPEELQKREEEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMVLENVKEMWTEVSKPVNKDRYISK
MFLRGDSVIVVLRNPLIA

The query sequence (length=98) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8y6o:q 104 96 0.9796 0.9231 1.0000 2.09e-67 7a5p:h, 7abg:a, 7abi:a, 6ah0:k, 6ah0:P, 6ahd:P, 6ahd:k, 8ch6:l, 8ch6:4, 7dvq:k, 8h6e:2c, 8h6j:2c, 8h6k:4c, 8h6k:2c, 8h6l:4c, 8h6l:2c, 8i0w:k, 6id0:k, 6id1:k, 5o9z:h, 5o9z:a, 4pjo:R, 7qtt:l, 8qzs:42, 7w59:k, 7w5a:k, 7w5b:k, 5xjc:k, 8y7e:k, 5yzg:k, 5z56:k, 5z57:k, 5z58:k
2 4wzj:KK 104 104 0.9694 0.9135 0.9135 1.76e-63 7abg:h, 7abi:h, 6ahd:c, 7b0y:e, 8c6j:m, 8c6j:a, 7evo:a, 9fmd:k, 9fmd:d, 8h6e:5c, 8h6e:4c, 8h6j:5c, 8h6j:4c, 8h6k:5c, 8h6l:5c, 8hk1:a, 8i0p:c, 8i0p:h, 8i0r:c, 8i0r:h, 8i0s:c, 8i0s:h, 8i0t:h, 8i0u:c, 8i0u:h, 8i0v:c, 8i0v:h, 8i0w:c, 6icz:d, 6id0:d, 6id1:d, 5mqf:h, 5mqf:a, 4pjo:D, 4pjo:d, 4pjo:r, 8q7q:c, 8q7v:c, 8q7w:c, 8q7x:c, 8q91:j, 6qdv:m, 6qdv:j, 8qo9:22, 8qo9:52, 8qo9:42, 6qw6:42, 6qw6:52, 6qx9:12, 6qx9:52, 6qx9:22, 6qx9:42, 8qxd:22, 8qxd:42, 8qxd:52, 8qzs:52, 8qzs:22, 8r08:12, 8r08:42, 8r08:22, 8r08:52, 8r09:22, 8r09:52, 8r09:42, 8r0a:52, 8r0a:42, 8r0a:22, 8r0b:22, 8r0b:42, 8r0b:52, 8rc0:j, 8rm5:22, 8rm5:52, 8rm5:42, 8ro2:d, 7vpx:a, 7vpx:i, 7w59:d, 7w5a:d, 7w5b:d, 4wzj:D, 4wzj:K, 4wzj:R, 4wzj:DD, 4wzj:RR, 4wzj:DDD, 4wzj:KKK, 4wzj:RRR, 4wzj:DDDD, 4wzj:KKKK, 4wzj:RRRR, 5xjc:d, 6y53:h, 6y5q:h, 8y6o:c, 8y6o:j, 5yzg:d, 5z56:d, 5z57:d, 5z58:d
3 8ro0:d 94 93 0.7653 0.7979 0.8065 6.72e-51 8ro1:d
4 3jb9:G 95 91 0.6735 0.6947 0.7253 3.87e-43 3jb9:l
5 6n7p:M 107 80 0.4898 0.4486 0.6000 9.72e-31 7b9v:m, 7b9v:j, 6bk8:a, 7dco:n, 6exn:m, 6exn:j, 6g90:i, 6g90:u, 5gam:j, 5gan:m, 5gan:j, 5gao:m, 5gm6:g, 5gmk:g, 5gmk:e, 6j6g:g, 6j6g:e, 6j6h:g, 6j6h:e, 6j6n:g, 6j6n:e, 6j6q:g, 6j6q:e, 3jcm:Q, 3jcm:U, 5lj3:j, 5lj3:m, 5lj5:j, 5lj5:m, 5mps:j, 5mq0:j, 6n7r:M, 6n7x:M, 5nrl:u, 5nrl:m, 5nrl:i, 7oqb:u, 7oqc:i, 7oqe:i, 7oqe:u, 8w2o:M, 5wsg:g, 5wsg:W, 5y88:g, 5y88:n, 5ylz:g, 5ylz:n, 5zwm:R, 5zwm:c, 5zwm:n, 5zwn:c, 5zwo:c, 5zwo:R, 5zwo:n
6 6qw6:63 85 81 0.2653 0.3059 0.3210 4.23e-09 6ah0:r, 6qx9:63, 8qxd:63, 8r08:63, 8r09:63, 8r0a:63, 8r0b:63, 8rm5:63
7 6ppn:C 75 73 0.2449 0.3200 0.3288 3.30e-08 6ppn:K, 6ppp:C, 6ppp:K, 6ppq:C, 6ppv:C
8 1loj:C 77 81 0.2551 0.3247 0.3086 8.11e-07 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
9 5vsu:C 81 75 0.2347 0.2840 0.3067 1.03e-06 6aso:C, 4c8q:C, 5gan:3, 4m7a:J, 4m7a:C, 4m7d:J, 4m7d:C, 5nrl:3
10 5mkn:d 72 73 0.2551 0.3472 0.3425 4.49e-06 5mki:C, 5mki:D, 5mki:E, 5mki:F, 5mki:G, 5mki:I, 5mki:J, 5mki:K, 5mki:L, 5mkn:A, 5mkn:G, 5mkn:B, 5mkn:C, 5mkn:D, 5mkn:E, 5mkn:F, 5mkn:H, 5mkn:I, 5mkn:J, 5mkn:K, 5mkn:L, 5mkn:M, 5mkn:N, 5mkn:O, 5mkn:P, 5mkn:Q, 5mkn:R, 5mkn:T, 5mkn:U, 5mkn:V, 5mkn:W, 5mkn:X, 5mkn:Y, 5mkn:Z, 5mkn:a, 5mkn:b
11 6v4x:D 106 77 0.2347 0.2170 0.2987 1.06e-04
12 1i5l:C 74 78 0.2347 0.3108 0.2949 1.31e-04 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H
13 1lnx:A 74 60 0.1837 0.2432 0.3000 0.001 1lnx:B, 1lnx:C, 1lnx:D, 1lnx:E, 1lnx:F, 1lnx:G
14 6ppq:A 69 49 0.1327 0.1884 0.2653 0.004 6ppv:A
15 6exn:r 75 58 0.1633 0.2133 0.2759 0.005 7b9v:r, 7b9v:g, 6bk8:d, 7dco:k, 6exn:g, 6g90:g, 6g90:y, 5gam:g, 5gan:r, 5gan:g, 5gao:r, 5gm6:j, 5gmk:j, 5gmk:x, 6j6g:j, 6j6g:x, 6j6h:j, 6j6h:x, 6j6n:j, 6j6n:x, 6j6q:j, 6j6q:x, 5lj3:g, 5lj5:g, 5mps:g, 5mq0:g, 6n7p:Q, 6n7r:Q, 6n7x:Q, 5nrl:y, 5nrl:r, 5nrl:g, 7oqb:y, 7oqc:g, 7oqe:y, 8w2o:Q, 5wsg:j, 5wsg:K, 5y88:d, 5y88:k, 5ylz:d, 5ylz:k, 5zwm:V, 5zwm:k, 5zwn:g, 5zwo:k
16 1m8v:A 72 74 0.2347 0.3194 0.3108 0.007 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
17 8ro0:b 98 60 0.1429 0.1429 0.2333 0.087 8ro1:b
18 6tfl:A 62 42 0.1224 0.1935 0.2857 0.088 6tfl:B, 6tfl:C, 6tfl:D, 6tfl:E, 6tfl:F, 6tfl:G, 6tfl:H, 6tfl:I, 6tfl:J, 6tfl:K, 6tfl:L, 6tfl:M, 6tfl:N
19 3jb9:H 76 75 0.1837 0.2368 0.2400 0.12 3jb9:m
20 6qw6:68 95 70 0.1837 0.1895 0.2571 0.14 6ahd:z, 8h6e:6g, 8h6j:6g, 8h6k:6g, 8h6l:6g, 6qx9:68, 8qxd:68, 8r08:68, 8r09:68, 8r0a:68, 8r0b:68, 8rm5:68
21 3swn:A 76 74 0.1837 0.2368 0.2432 0.15 6ppq:E, 6ppv:E, 3swn:D, 3swn:P, 3swn:S
22 6v4x:B 76 74 0.1735 0.2237 0.2297 0.18
23 7abg:j 81 75 0.1531 0.1852 0.2000 0.27 7a5p:j, 7a5p:e, 7abi:j, 6ah0:c, 6ahd:e, 7b0y:g, 8c6j:p, 8c6j:e, 8ch6:i, 8ch6:1, 7dvq:e, 7dvq:l, 9fmd:l, 9fmd:e, 8h6e:5e, 8h6e:4e, 8h6j:5e, 8h6j:4e, 8h6k:5e, 8h6l:5e, 8i0p:e, 8i0p:j, 8i0r:e, 8i0r:j, 8i0s:e, 8i0s:j, 8i0t:e, 8i0t:j, 8i0u:e, 8i0u:j, 8i0v:e, 8i0v:j, 8i0w:e, 8i0w:l, 6icz:e, 6id0:e, 6id1:e, 5mqf:j, 5mqf:c, 5o9z:j, 4pjo:E, 4pjo:e, 4pjo:S, 4pjo:s, 8q7q:e, 8q7v:e, 8q7w:e, 8q7x:e, 6qdv:p, 6qdv:e, 8qo9:2e, 8qo9:5e, 8qo9:4e, 7qtt:i, 6qw6:4e, 6qw6:5e, 6qx9:1e, 6qx9:5e, 6qx9:2e, 6qx9:4e, 8qxd:2e, 8qxd:4e, 8qzs:5e, 8qzs:2e, 8qzs:4e, 8r08:1e, 8r08:2e, 8r08:4e, 8r09:2e, 8r09:5e, 8r09:4e, 8r0a:5e, 8r0a:2e, 8r0a:4e, 8r0b:4e, 8r0b:5e, 8rm5:2e, 8rm5:5e, 8rm5:4e, 8ro2:e, 6v4x:E, 7vpx:l, 7w59:e, 7w59:l, 7w5a:e, 7w5a:l, 7w5b:e, 7w5b:l, 4wzj:E, 4wzj:L, 4wzj:S, 4wzj:EE, 4wzj:LL, 4wzj:SS, 4wzj:EEE, 4wzj:LLL, 4wzj:SSS, 4wzj:EEEE, 4wzj:LLLL, 4wzj:SSSS, 5xjc:e, 5xjc:l, 8y6o:e, 8y6o:l, 8y6o:s, 8y7e:l, 5yzg:e, 5yzg:l, 5z56:e, 5z56:l, 5z57:e, 5z57:l, 5z58:e, 5z58:l
24 3jb9:E 98 55 0.1327 0.1327 0.2364 0.37 3jb9:b
25 6bk8:f 80 52 0.1531 0.1875 0.2885 0.64 6bk8:k, 7dco:a, 7dco:h, 6exn:k, 6exn:b, 6g90:s, 5gam:b, 5gan:k, 5gan:b, 5gao:k, 5gm6:k, 5gmk:k, 5gmk:s, 3jcm:S, 5lj3:b, 5lj5:b, 5mps:b, 5mq0:k, 5mq0:b, 5nrl:s, 5nrl:k, 5nrl:b, 7oqb:s, 7oqe:s, 5wsg:k, 5wsg:F, 5y88:a, 5y88:h, 5ylz:a, 5ylz:h, 5zwm:P, 5zwm:a, 5zwm:h, 5zwo:a, 5zwo:P
26 7b9v:p 77 47 0.1327 0.1688 0.2766 0.65 7b9v:e, 6bk8:c, 7dco:i, 6exn:p, 6exn:e, 6g90:e, 6g90:w, 5gan:p, 5gao:p, 5gm6:i, 5gmk:i, 5gmk:u, 6j6g:i, 6j6g:u, 6j6h:i, 6j6h:u, 6j6n:i, 6j6n:u, 6j6q:i, 6j6q:u, 5mps:e, 5mq0:e, 6n7p:O, 6n7r:O, 6n7x:O, 5nrl:w, 5nrl:p, 5nrl:e, 7oqb:w, 7oqc:e, 7oqe:w, 8w2o:O, 5wsg:i, 5wsg:G, 5y88:b, 5y88:i, 5ylz:b, 5ylz:i, 5zwm:T, 5zwm:i, 5zwn:e, 5zwo:T, 5zwo:i
27 9fmd:b 87 52 0.1327 0.1494 0.2500 0.83 7a5p:m, 7a5p:b, 7abg:f, 7abi:f, 6ah0:U, 8ch6:n, 5o9z:f, 6qdv:b, 7qtt:n, 4wzj:I, 4wzj:P, 4wzj:BB, 4wzj:II, 4wzj:PP, 4wzj:BBB, 4wzj:III, 4wzj:PPP, 4wzj:BBBB, 4wzj:IIII, 4wzj:PPPP
28 3b99:B 415 32 0.1224 0.0289 0.3750 0.94
29 3b98:A 446 32 0.1224 0.0269 0.3750 1.1 3b98:B, 3b99:A
30 7pkt:m 177 43 0.1224 0.0678 0.2791 1.1
31 7w59:b 102 57 0.1429 0.1373 0.2456 1.4 7abg:m, 7abi:m, 6ahd:a, 7b0y:j, 8c6j:b, 8ch6:8, 7dvq:i, 9fmd:i, 8h6e:5a, 8h6e:4a, 8h6j:5a, 8h6j:4a, 8h6k:5a, 8h6l:5a, 8i0p:a, 8i0p:m, 8i0r:a, 8i0r:m, 8i0s:m, 8i0t:a, 8i0t:m, 8i0u:m, 8i0v:a, 8i0v:m, 8i0w:a, 8i0w:i, 6icz:i, 4pjo:B, 4pjo:b, 4pjo:P, 4pjo:p, 8q7q:b, 8q7v:b, 8q7w:b, 8q7x:b, 8q91:h, 6qdv:k, 8qo9:5b, 8qo9:4b, 6qw6:4b, 6qw6:5b, 6qx9:1b, 6qx9:5b, 6qx9:2b, 6qx9:4b, 8qxd:4b, 8qxd:5b, 8qzs:5b, 8qzs:2b, 8r08:1b, 8r08:4b, 8r08:5b, 8r09:5b, 8r0a:5b, 8r0b:5b, 8rc0:h, 8rm5:2b, 8rm5:5b, 8ro2:b, 7vpx:k, 7w59:i, 7w5a:b, 7w5a:i, 7w5b:b, 7w5b:i, 4wzj:B, 5xjc:b, 5xjc:i, 8y6o:a, 8y6o:h, 8y6o:o, 8y7e:i, 5yzg:b, 5yzg:i, 5z56:b, 5z56:i, 5z57:b, 5z57:i, 5z58:b, 5z58:i
32 6rj9:C 836 61 0.1735 0.0203 0.2787 2.0 6rjd:C
33 4gfh:A 1102 47 0.1429 0.0127 0.2979 4.6 4gfh:F, 3l4j:A, 3l4k:A, 1pvg:A, 1pvg:B, 1qzr:A, 1qzr:B, 2rgr:A
34 6ppn:B 94 64 0.1633 0.1702 0.2500 4.9 6ppn:J, 6ppp:B, 6ppp:J, 6ppq:B, 6ppv:B
35 8ro0:n 77 53 0.1429 0.1818 0.2642 5.2 8ro0:g, 8ro1:g
36 6jig:A 480 40 0.1327 0.0271 0.3250 5.7 6lk4:A
37 9ash:A 753 38 0.1020 0.0133 0.2632 6.0 9asi:A, 6xn3:A, 6xn4:A, 6xn5:A, 6xn7:A
38 5gky:A 3660 52 0.1633 0.0044 0.3077 6.7 5gky:C, 5gky:E, 5gky:G, 5gkz:A, 5gkz:C, 5gkz:E, 5gkz:G, 5gl0:A, 5gl0:C, 5gl0:E, 5gl0:G, 5gl1:A, 5gl1:C, 5gl1:E, 5gl1:G
39 7ziu:B 606 23 0.0714 0.0116 0.3043 6.7 7ziu:A
40 6n7r:K 124 69 0.1939 0.1532 0.2754 7.1 7b9v:k, 7b9v:b, 6g90:b, 6j6g:k, 6j6g:s, 6j6h:k, 6j6h:s, 6j6n:k, 6j6n:s, 6j6q:k, 6j6q:s, 6n7p:K, 6n7x:K, 7oqc:b, 7oqe:b, 8w2o:K, 5zwn:a
41 6ppn:H 94 38 0.1122 0.1170 0.2895 7.6 6ppn:P, 6ppp:H, 6ppp:P
42 3cd5:A 425 82 0.2143 0.0494 0.2561 9.5 3bgl:A, 3bgl:B, 3bgl:C, 3bgl:D, 3cct:A, 3cct:B, 3cct:C, 3cct:D, 3ccw:A, 3ccw:B, 3ccw:C, 3ccw:D, 3ccz:A, 3ccz:B, 3ccz:C, 3ccz:D, 3cd0:A, 3cd0:B, 3cd0:C, 3cd0:D, 3cd5:B, 3cd5:C, 3cd5:D, 3cd7:A, 3cd7:B, 3cd7:C, 3cd7:D, 3cda:A, 3cda:B, 3cda:C, 3cda:D, 3cdb:A, 3cdb:B, 3cdb:C, 3cdb:D, 1dq8:A, 1dq8:B, 1dq8:C, 1dq8:D, 1dq9:A, 1dq9:B, 1dq9:C, 1dq9:D, 1dqa:A, 1dqa:B, 1dqa:C, 1dqa:D, 1hw8:A, 1hw8:B, 1hw8:C, 1hw8:D, 1hw9:A, 1hw9:B, 1hw9:C, 1hw9:D, 1hwi:A, 1hwi:B, 1hwi:C, 1hwi:D, 1hwj:A, 1hwj:B, 1hwj:C, 1hwj:D, 1hwk:A, 1hwk:B, 1hwk:C, 1hwk:D, 1hwl:A, 1hwl:B, 1hwl:C, 1hwl:D, 2q1l:A, 2q1l:B, 2q1l:C, 2q1l:D, 2q6b:A, 2q6b:B, 2q6b:C, 2q6b:D, 2q6c:A, 2q6c:B, 2q6c:C, 2q6c:D, 2r4f:A, 2r4f:B, 2r4f:C, 2r4f:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218