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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLT
GYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKI
HSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGALFAAMLL
AWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDPEIVVQATVL

The query sequence (length=310) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4en4:A 310 310 0.9968 0.9968 0.9968 0.0 2ajp:A, 2ajp:B, 4en4:B, 4eoh:A, 4eoh:B, 3fhx:A, 3fhx:B, 3fhy:A, 3fhy:B, 3keu:A, 3keu:B, 8wr2:A, 8wr2:B, 2yxt:A, 2yxt:B, 2yxu:A, 2yxu:B
2 1rfu:A 312 310 0.8645 0.8590 0.8645 0.0 1lhr:A, 1lhr:B, 1rft:A, 1rfu:B, 1rfu:C, 1rfu:D, 1rfu:E, 1rfu:F, 1rfu:G, 1rfu:H, 1rfv:A, 1rfv:B, 1ygj:A, 1ygk:A, 1yhj:A
3 6yk0:A 309 309 0.8581 0.8608 0.8608 0.0 6yk0:B, 6yk0:C, 6yk0:D, 6yk1:A, 6yk1:B, 6yk1:C, 6yk1:D
4 6k8z:B 298 313 0.3613 0.3758 0.3578 8.15e-53 6k8z:A, 6k90:A, 6k90:B, 6k91:A, 6k91:B, 6k92:A, 6k92:B
5 3zs7:A 277 310 0.3613 0.4043 0.3613 5.80e-52
6 5b6a:A 288 309 0.2903 0.3125 0.2913 4.15e-38
7 1td2:A 287 180 0.2065 0.2230 0.3556 1.36e-31 1td2:B
8 6su9:A 295 314 0.2839 0.2983 0.2803 2.11e-30 6su9:B
9 4s1h:A 287 272 0.2419 0.2613 0.2757 1.52e-29 4s1h:B, 4s1i:A, 4s1i:B
10 5zwb:A 271 268 0.2194 0.2509 0.2537 1.23e-19 5zw9:A, 5zwa:A, 5zwa:B
11 2ddo:A 263 241 0.2065 0.2433 0.2656 1.28e-18 2ddw:A, 2ddw:B
12 3mbh:A 290 164 0.1581 0.1690 0.2988 4.13e-09 3mbh:B, 3mbh:C, 3mbh:D, 3mbh:E, 3mbh:F, 3mbj:A
13 7r8y:A 228 129 0.1355 0.1842 0.3256 1.11e-06
14 1gqt:B 307 49 0.0677 0.0684 0.4286 1.82e-05 1gqt:A, 1gqt:C, 1gqt:D, 1rk2:A, 1rk2:B, 1rk2:C, 1rk2:D, 1rkd:A, 1rks:A
15 2i5b:A 269 142 0.1258 0.1450 0.2746 2.51e-05 2i5b:C, 2i5b:D, 2i5b:B, 2i5b:E
16 4xck:A 306 49 0.0581 0.0588 0.3673 4.26e-04 4xck:B, 4xck:C, 4xck:D, 4xda:A, 4xda:B, 4xda:C, 4xda:D
17 7l07:A 214 51 0.0645 0.0935 0.3922 0.004
18 3hyo:A 273 143 0.1323 0.1502 0.2867 0.007 3ibq:A
19 6a8a:A 327 46 0.0516 0.0489 0.3478 0.045 6a8a:B, 6a8b:A, 6a8b:B, 6a8c:A, 6a8c:B, 5zwy:A, 5zwy:B
20 4c5k:D 276 77 0.0839 0.0942 0.3377 0.056 4c5k:A, 4c5k:B, 4c5k:C, 4c5l:A, 4c5l:B, 4c5l:C, 4c5l:D, 4c5m:A, 4c5m:B, 4c5m:C, 4c5m:D, 4c5n:A, 4c5n:B, 4c5n:C, 4c5n:D
21 4ywr:A 228 62 0.0710 0.0965 0.3548 0.078
22 7w93:A 307 123 0.0903 0.0912 0.2276 0.17 7vsk:A, 7vte:A, 7vte:B, 7vte:C, 7vte:D, 7vtf:A, 7vtf:B, 7vtf:C, 7vtf:D, 7vtg:A, 7vtg:B, 7vtg:C, 7vtg:D, 7vva:A, 7vva:B, 7vva:C, 7vva:D
23 5c41:A 317 161 0.1194 0.1167 0.2298 0.38 5byf:A, 5byf:B, 5c3y:A, 5c3y:B, 5c3y:C, 5c3y:D, 5c3y:E, 5c3y:F, 5c3y:G, 5c3y:H, 5c3y:I, 5c3y:J, 5c3y:K, 5c3y:L, 5c3z:A, 5c3z:B, 5c40:A, 5c40:B, 5c41:B, 5c41:C, 5c41:D, 2fv7:A, 2fv7:B, 6wjz:A, 6wjz:B, 6wk0:A, 6wk0:B, 6wk0:C, 6wk0:D
24 1rjn:B 275 109 0.0839 0.0945 0.2385 1.3 1q51:A, 1q51:C, 1q51:D, 1q51:E, 1q51:F, 1q51:G, 1q51:H, 1q51:I, 1q51:J, 1q51:K, 1q51:L, 1rjm:A, 1rjm:B, 1rjm:C, 1rjn:A, 1rjn:C, 3t8a:B, 3t8a:C
25 4yjx:C 84 52 0.0548 0.2024 0.3269 1.9 4yjx:A, 4yjx:B, 4yjx:D, 4yka:A, 4yka:B, 4yka:C, 4yka:D
26 7sgl:A 3852 72 0.0710 0.0057 0.3056 2.3
27 4q94:A 129 69 0.0581 0.1395 0.2609 4.2 9b9l:A, 4q94:B, 4q96:A, 4q96:B, 4q96:D, 4q96:E
28 7sva:A 792 145 0.1065 0.0417 0.2276 4.3 7swf:A, 7swq:A
29 8qjp:A 250 87 0.0774 0.0960 0.2759 5.1 8qjl:A, 8qjm:A, 8qjm:B, 8qjn:A, 8qjn:B, 8qjo:A, 8qjo:B, 8qjp:B, 8qjq:A, 8qjq:B
30 4qii:B 301 121 0.0935 0.0963 0.2397 5.4 1q51:B, 4qii:A, 4qii:F, 4qii:E, 4qii:C, 4qii:D, 4qii:G, 4qii:L, 4qii:H, 4qii:K, 4qii:I, 4qii:J, 4qij:A, 4qij:F, 4qij:B, 4qij:E, 4qij:C, 4qij:D, 4qij:G, 4qij:K, 4qij:H, 4qij:J, 4qij:I, 4qij:L
31 2v5k:A 260 40 0.0452 0.0538 0.3500 5.6 4b5s:A, 4b5s:B, 4b5t:A, 4b5t:B, 4b5u:A, 4b5u:B, 4b5v:A, 4b5v:B, 4b5w:A, 4b5w:B, 4b5w:C, 4b5w:D, 4b5w:E, 4b5w:F, 2v5k:B
32 8xha:A 401 44 0.0452 0.0349 0.3182 5.6 8i7u:C, 8i7u:F, 8i7u:A, 8i7u:E, 8i7u:B, 8i7u:D, 8xha:B, 8xhd:A, 8xhd:B, 8xhk:C, 8xhk:A, 8xhk:B, 8xhk:E, 8xhk:D, 8xhk:F
33 6n6q:B 448 45 0.0484 0.0335 0.3333 5.9 6n6q:A, 6n6q:C, 6n6q:D
34 5y3r:C 3636 71 0.0645 0.0055 0.2817 6.6
35 3m5p:A 542 66 0.0548 0.0314 0.2576 6.6 3q7i:A, 3q88:A
36 8gna:A 1188 51 0.0677 0.0177 0.4118 6.7
37 8jj9:B 299 25 0.0387 0.0401 0.4800 7.4 8jj9:A
38 7y80:A 1218 49 0.0677 0.0172 0.4286 7.9 8gu6:A
39 7y84:A 1242 49 0.0677 0.0169 0.4286 7.9 7x7a:A, 7x7r:A, 7xc7:A, 7y83:A, 7y85:A
40 8d8n:B 1256 49 0.0677 0.0167 0.4286 7.9 8d9e:B, 8d9i:B, 7y81:A
41 7xss:B 1282 49 0.0677 0.0164 0.4286 7.9 8d9f:B, 8d9h:B, 7x8a:A, 7xso:A, 7xsp:B, 7xt4:B
42 7y8t:A 1298 49 0.0677 0.0162 0.4286 7.9 8d9g:B, 7xsq:A, 7xsr:B, 7y8y:A
43 7y82:A 1341 49 0.0677 0.0157 0.4286 7.9
44 8d97:A 1600 49 0.0677 0.0131 0.4286 8.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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