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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DYLRELLKLELQGIKQYREALEYVKLPVLAKILEDEEKHIEWLETILG

The query sequence (length=48) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1ec5:A 48 48 0.9792 0.9792 0.9792 1.05e-25 1ec5:C, 1ec5:B, 1jm0:A, 1jm0:F, 1jm0:B, 1jm0:C, 1jm0:D, 1jm0:E, 1jmb:A, 1jmb:B, 1jmb:C, 1lt1:A, 1lt1:B, 1lt1:C, 1lt1:D, 1lt1:E, 1lt1:F, 1lt1:G, 1lt1:H, 1ovr:A, 1ovr:D, 1ovr:B, 1ovr:C, 1ovu:A, 1ovu:B, 1ovu:C, 1ovu:D, 1ovv:A, 1ovv:F, 1ovv:B, 1ovv:C, 1ovv:D, 1ovv:E
2 2kik:A 48 48 0.9167 0.9167 0.9167 3.83e-24 2kik:B
3 1u7j:A 49 48 0.7917 0.7755 0.7917 1.29e-18 1u7j:B
4 7jh6:A 174 39 0.7708 0.2126 0.9487 1.37e-17 7jh6:B, 7jh6:C, 7jh6:D
5 7jh6:A 174 18 0.3750 0.1034 1.0000 2.32e-05 7jh6:B, 7jh6:C, 7jh6:D
6 7jh6:A 174 17 0.3333 0.0920 0.9412 0.002 7jh6:B, 7jh6:C, 7jh6:D
7 1u7m:A 53 52 0.7500 0.6792 0.6923 7.38e-16 5c39:A, 5c39:B, 1mft:A, 1mft:B, 1u7m:B
8 5vjs:A 196 47 0.6875 0.1684 0.7021 1.81e-11 8d9p:A, 5vjt:A, 5vju:A
9 5vjs:A 196 19 0.3750 0.0918 0.9474 1.78e-04 8d9p:A, 5vjt:A, 5vju:A
10 5vjs:A 196 19 0.3542 0.0867 0.8947 0.001 8d9p:A, 5vjt:A, 5vju:A
11 2hz8:A 115 47 0.5000 0.2087 0.5106 1.38e-08 2lfd:A, 2lff:A
12 1bcf:A 158 50 0.5000 0.1519 0.4800 1.15e-06 1bcf:B, 1bcf:C, 1bcf:D, 1bcf:E, 1bcf:F, 1bcf:G, 1bcf:H, 1bcf:I, 1bcf:J, 1bcf:K, 1bcf:L, 1bfr:A, 1bfr:B, 1bfr:C, 1bfr:D, 1bfr:E, 1bfr:F, 1bfr:G, 1bfr:H, 1bfr:I, 1bfr:J, 1bfr:K, 1bfr:L, 1bfr:M, 1bfr:N, 1bfr:O, 1bfr:P, 1bfr:Q, 1bfr:R, 1bfr:S, 1bfr:T, 1bfr:U, 1bfr:V, 1bfr:W, 1bfr:X, 4cvp:A, 4cvr:A, 4cvt:A, 3e1j:A, 3e1j:B, 3e1j:C, 3e1j:D, 3e1j:E, 3e1j:F, 3e1j:G, 3e1j:H, 3e1j:I, 3e1j:J, 3e1j:K, 3e1j:L, 3e1l:A, 3e1l:B, 3e1l:C, 3e1l:D, 3e1l:E, 3e1l:F, 3e1l:G, 3e1l:H, 3e1l:I, 3e1l:J, 3e1l:K, 3e1l:L, 3e1m:A, 3e1m:B, 3e1m:C, 3e1m:D, 3e1m:E, 3e1m:F, 3e1m:G, 3e1m:H, 3e1m:I, 3e1m:J, 3e1m:K, 3e1m:L, 3e1n:A, 3e1n:B, 3e1n:C, 3e1n:D, 3e1n:E, 3e1n:F, 3e1n:G, 3e1n:H, 3e1n:I, 3e1n:J, 3e1n:K, 3e1n:L, 3e1o:A, 3e1o:B, 3e1o:C, 3e1o:D, 3e1o:E, 3e1o:F, 3e1o:G, 3e1o:H, 3e1o:I, 3e1o:J, 3e1o:K, 3e1o:L, 3e1p:A, 3e1p:B, 3e1p:C, 3e1p:D, 3e1p:E, 3e1p:F, 3e1p:G, 3e1p:H, 3e1p:I, 3e1p:J, 3e1p:K, 3e1p:L, 3e1q:A, 3e1q:B, 3e1q:C, 3e1q:D, 3e1q:E, 3e1q:F, 3e1q:G, 3e1q:H, 3e1q:I, 3e1q:J, 3e1q:K, 3e1q:L, 3e2c:A, 3e2c:B, 3ghq:A, 3ghq:B, 3ghq:C, 3ghq:D, 3ghq:E, 3ghq:F, 3ghq:G, 3ghq:H, 3ghq:I, 3ghq:J, 3ghq:K, 3ghq:L, 2htn:A, 2htn:B, 2htn:C, 2htn:D, 2htn:E, 2htn:F, 2htn:G, 2htn:H, 6p8k:A, 6p8k:B, 6p8k:C, 6p8k:D, 6p8k:E, 6p8k:F, 6p8k:G, 6p8k:H, 6p8k:I, 6p8k:J, 6p8k:K, 6p8k:L, 6p8l:A, 6p8l:B, 6p8l:C, 6p8l:D, 6p8l:E, 6p8l:F, 6p8l:G, 6p8l:H, 6p8l:I, 6p8l:J, 6p8l:K, 6p8l:L, 2vxi:A, 2vxi:B, 2vxi:C, 2vxi:D, 2vxi:E, 2vxi:F, 2vxi:G, 2vxi:H, 2vxi:I, 2vxi:J, 2vxi:K, 2vxi:L, 2y3q:A, 2y3q:B, 2y3q:C, 2y3q:D, 2y3q:E, 2y3q:F, 2y3q:G, 2y3q:H, 2y3q:I, 2y3q:J, 2y3q:K, 2y3q:L
13 4e6k:A 157 49 0.4792 0.1465 0.4694 7.02e-05 5d8o:A, 5d8o:B, 5d8o:E, 5d8o:D, 5d8o:F, 5d8o:K, 5d8o:C, 5d8o:I, 5d8o:H, 5d8o:J, 5d8o:L, 5d8p:A, 5d8p:B, 5d8p:C, 5d8p:I, 5d8p:D, 5d8p:E, 5d8p:F, 5d8p:G, 5d8p:H, 5d8p:J, 5d8p:K, 5d8p:L, 5d8q:A, 5d8q:B, 5d8q:C, 5d8q:H, 5d8q:E, 5d8q:G, 5d8q:I, 5d8q:D, 5d8q:J, 5d8q:F, 5d8q:K, 5d8q:L, 5d8r:A, 5d8r:B, 5d8r:E, 5d8r:D, 5d8r:C, 5d8r:I, 5d8r:H, 5d8r:J, 5d8r:F, 5d8r:K, 5d8r:L, 5d8s:A, 5d8s:B, 5d8s:C, 5d8s:H, 5d8s:D, 5d8s:J, 5d8s:E, 5d8s:G, 5d8s:F, 5d8s:K, 5d8s:I, 5d8s:L, 5d8x:A, 5d8x:B, 5d8x:C, 5d8x:D, 5d8x:E, 5d8x:F, 5d8x:G, 5d8x:H, 5d8x:I, 5d8x:J, 5d8x:K, 5d8x:L, 5d8x:M, 5d8x:N, 5d8x:O, 5d8x:P, 5d8x:Q, 5d8x:R, 5d8x:S, 5d8x:T, 5d8x:U, 5d8x:V, 5d8x:W, 5d8x:X, 5d8y:A, 5d8y:B, 5d8y:C, 5d8y:D, 5d8y:E, 5d8y:F, 5d8y:G, 5d8y:H, 5d8y:I, 5d8y:J, 5d8y:K, 5d8y:L, 5d8y:M, 5d8y:N, 5d8y:O, 5d8y:P, 5d8y:Q, 5d8y:R, 5d8y:S, 5d8y:T, 5d8y:U, 5d8y:V, 5d8y:W, 5d8y:X, 4e6k:B, 4e6k:C, 4e6k:D, 4e6k:E, 4e6k:F, 3is7:A, 3is7:B, 3is7:C, 3is7:D, 3is7:E, 3is7:F, 3is7:G, 3is7:H, 3is7:I, 3is7:J, 3is7:K, 3is7:L, 3is7:M, 3is7:N, 3is7:O, 3is7:P, 3is7:Q, 3is7:R, 3is7:S, 3is7:T, 3is7:U, 3is7:V, 3is7:W, 3is7:X, 3is8:A, 3is8:B, 3is8:C, 3is8:D, 3is8:E, 3is8:F, 3is8:G, 3is8:H, 3is8:I, 3is8:J, 3is8:K, 3is8:L, 3is8:M, 3is8:N, 3is8:O, 3is8:P, 3is8:Q, 3is8:R, 3is8:S, 3is8:T, 3is8:U, 3is8:V, 3is8:W, 3is8:X, 3ise:A, 3ise:B, 3ise:H, 3ise:C, 3ise:D, 3ise:E, 3ise:F, 3ise:G, 3ise:I, 3ise:J, 3ise:K, 3ise:L, 3ise:M, 3ise:N, 3ise:X, 3ise:O, 3ise:P, 3ise:Q, 3ise:R, 3ise:S, 3ise:T, 3ise:U, 3ise:V, 3ise:W, 3isf:A, 3isf:B, 3isf:C, 3isf:D, 3isf:E, 3isf:F, 7k5e:A, 7k5e:B, 7k5e:E, 7k5e:C, 7k5e:I, 7k5e:D, 7k5e:F, 7k5e:K, 7k5e:G, 7k5e:H, 7k5e:J, 7k5e:L, 7k5f:A, 7k5f:B, 7k5f:E, 7k5f:C, 7k5f:I, 7k5f:D, 7k5f:F, 7k5f:K, 7k5f:H, 7k5f:J, 7k5f:L, 7k5g:A, 7k5g:B, 7k5g:E, 7k5g:C, 7k5g:I, 7k5g:D, 7k5g:F, 7k5g:K, 7k5g:H, 7k5g:J, 7k5g:L, 7k5h:A, 7k5h:B, 7k5h:E, 7k5h:C, 7k5h:I, 7k5h:D, 7k5h:F, 7k5h:K, 7k5h:H, 7k5h:J, 7k5h:L, 6nlg:B, 6nlg:A, 6nlg:C, 6nlg:D, 6nli:A, 6nli:E, 6nli:J, 6nli:K, 6nli:B, 6nli:C, 6nli:G, 6nli:L, 6nli:I, 6nli:D, 6nli:F, 6nli:H, 6nlj:D, 6nlj:B, 6nlj:E, 6nlj:F, 6nlj:K, 6nlk:A, 6nlk:E, 6nlk:J, 6nlk:K, 6nlk:B, 6nlk:C, 6nlk:G, 6nlk:L, 6nlk:I, 6nlk:D, 6nlk:F, 6nlk:H, 6nll:A, 6nll:E, 6nll:J, 6nll:K, 6nll:B, 6nll:C, 6nll:G, 6nll:L, 6nll:I, 6nll:D, 6nll:F, 6nll:H, 6nlm:A, 6nlm:E, 6nlm:J, 6nlm:K, 6nlm:B, 6nlm:C, 6nlm:G, 6nlm:L, 6nlm:I, 6nlm:D, 6nlm:F, 6nlm:H, 6nln:A, 6nln:E, 6nln:J, 6nln:K, 6nln:B, 6nln:C, 6nln:G, 6nln:L, 6nln:I, 6nln:D, 6nln:F, 6nln:H, 4to9:A, 4to9:B, 4to9:C, 4to9:D, 4to9:E, 4to9:F, 4to9:G, 4to9:H, 4to9:I, 4to9:J, 4to9:K, 4to9:L, 4to9:M, 4to9:N, 4to9:O, 4to9:P, 4to9:Q, 4to9:R, 4to9:S, 4to9:T, 4to9:U, 4to9:V, 4to9:W, 4to9:X, 4toa:A, 4toa:B, 4toa:C, 4toa:D, 4toa:E, 4toa:F, 4toa:G, 4toa:H, 4toa:I, 4toa:J, 4toa:K, 4toa:L, 4toa:M, 4toa:N, 4toa:O, 4toa:P, 4toa:Q, 4toa:R, 4toa:S, 4toa:T, 4toa:U, 4toa:V, 4toa:W, 4toa:X, 4tob:A, 4tob:B, 4tob:C, 4tob:D, 4tob:E, 4tob:F, 4tob:G, 4tob:H, 4tob:I, 4tob:J, 4tob:K, 4tob:L, 4tob:M, 4tob:N, 4tob:O, 4tob:P, 4tob:Q, 4tob:R, 4tob:S, 4tob:T, 4tob:U, 4tob:V, 4tob:W, 4tob:X, 4toc:A, 4toc:B, 4toc:C, 4toc:D, 4toc:J, 4toc:E, 4toc:F, 4toc:G, 4toc:H, 4toc:I, 4toc:Q, 4toc:K, 4toc:L, 4toc:M, 4toc:N, 4toc:O, 4toc:P, 4toc:R, 4toc:S, 4toc:T, 4toc:U, 4toc:V, 4toc:W, 4toc:X, 4tod:A, 4tod:B, 4tod:C, 4tod:D, 4tod:E, 4tod:F, 4tod:G, 4tod:H, 4tod:I, 4tod:J, 4tod:K, 4tod:L, 4tod:M, 4tod:N, 4tod:O, 4tod:P, 4tod:Q, 4tod:R, 4tod:S, 4tod:T, 4tod:U, 4tod:V, 4tod:W, 4tod:X, 4toe:A, 4toe:B, 4toe:C, 4toe:D, 4toe:E, 4toe:F, 4toe:G, 4toe:H, 4toe:I, 4toe:J, 4toe:K, 4toe:L, 4toe:M, 4toe:N, 4toe:O, 4toe:P, 4toe:Q, 4toe:R, 4toe:S, 4toe:T, 4toe:U, 4toe:V, 4toe:W, 4toe:X, 4tof:A, 4tof:B, 4tof:C, 4tof:D, 4tog:A, 4tog:B, 4tog:C, 4tog:D, 4toh:A, 4toh:B, 4toh:C, 4toh:D
14 2fkz:A 155 48 0.4167 0.1290 0.4167 0.009 2fkz:B, 2fkz:D, 2fkz:C, 2fkz:E, 2fkz:F, 2fkz:G, 2fkz:H, 2fl0:A, 2fl0:F, 2fl0:B, 2fl0:D, 2fl0:C, 2fl0:E, 2fl0:G, 2fl0:H, 1sof:A, 1sof:B, 1sof:C, 1sof:D, 1sof:E, 1sof:F, 1sof:G, 1sof:H
15 1jgc:A 160 53 0.3958 0.1187 0.3585 0.027 1jgc:B, 1jgc:C
16 2wtl:A 161 35 0.3333 0.0994 0.4571 0.029 3qb9:A, 3qb9:B, 3qb9:C, 3qb9:D, 3qb9:E, 3qb9:F, 3uof:A, 3uof:B, 3uof:C, 3uof:D, 3uof:E, 3uof:F, 3uoi:A, 3uoi:B, 3uoi:C, 3uoi:D, 3uoi:E, 3uoi:F, 3uoi:G, 3uoi:H, 3uoi:I, 3uoi:J, 3uoi:K, 3uoi:L, 3uoi:M, 3uoi:N, 3uoi:O, 3uoi:P, 3uoi:Q, 3uoi:R, 3uoi:S, 3uoi:T, 3uoi:U, 3uoi:V, 3uoi:W, 3uoi:X, 3uoi:a, 3uoi:b, 3uoi:c, 3uoi:d, 3uoi:e, 3uoi:f, 3uoi:g, 3uoi:h, 3uoi:i, 3uoi:j, 3uoi:k, 3uoi:l, 3uoi:m, 3uoi:n, 3uoi:o, 3uoi:p, 3uoi:q, 3uoi:r, 3uoi:s, 3uoi:t, 3uoi:u, 3uoi:v, 3uoi:w, 3uoi:x, 2wtl:B, 2wtl:C, 2wtl:D, 2wtl:E, 2wtl:F
17 5zur:B 155 46 0.3750 0.1161 0.3913 0.046 5zur:A, 5zur:C
18 3bkn:A 161 35 0.3333 0.0994 0.4571 0.068 3bkn:B, 3bkn:C, 3bkn:D, 3bkn:E, 3bkn:F, 3bkn:G, 3bkn:H, 3bkn:I, 3bkn:J, 3bkn:K, 3bkn:L
19 8jax:A 162 36 0.3125 0.0926 0.4167 0.13 8jax:B, 8jax:C, 8jax:D, 8jax:F, 8jax:E, 8jax:G, 8jax:H, 8jax:N, 8jax:I, 8jax:J, 8jax:K, 8jax:L, 8jax:M, 8jax:O, 8jax:P, 8jax:Q, 8jax:R, 8jax:S, 8jax:T, 8jax:U, 8jax:V, 8jax:W, 8jax:X, 8jb0:A, 8jb0:B, 8jb0:C, 8jb0:D, 8jb0:F, 8jb0:E, 8jb0:G, 8jb0:H, 8jb0:I, 8jb0:J, 8jb0:K, 8jb0:L, 8jb0:M, 8jb0:N, 8jb0:O, 8jb0:P, 8jb0:Q, 8jb0:R, 8jb0:S, 8jb0:T, 8jb0:U, 8jb0:V, 8jb0:W, 8jb0:X, 6k3o:A, 6k3o:B, 6k3o:C, 6k3o:D, 6k3o:F, 6k3o:E, 6k3o:G, 6k3o:H, 6k3o:I, 6k3o:J, 6k3o:K, 6k3o:L, 6k3o:M, 6k3o:N, 6k3o:O, 6k3o:P, 6k3o:Q, 6k3o:R, 6k3o:S, 6k3o:T, 6k3o:U, 6k3o:V, 6k3o:W, 6k3o:X, 6k43:A, 6k43:B, 6k43:C, 6k43:D, 6k43:F, 6k43:E, 6k43:G, 6k43:H, 6k43:I, 6k43:J, 6k43:K, 6k43:L, 6k43:M, 6k43:N, 6k43:O, 6k43:P, 6k43:Q, 6k43:R, 6k43:S, 6k43:T, 6k43:U, 6k43:V, 6k43:W, 6k43:X, 6k4m:A, 6k4m:B, 6k4m:C, 6k4m:D, 6k4m:F, 6k4m:E, 6k4m:G, 6k4m:H, 6k4m:N, 6k4m:I, 6k4m:J, 6k4m:K, 6k4m:L, 6k4m:M, 6k4m:O, 6k4m:P, 6k4m:Q, 6k4m:R, 6k4m:S, 6k4m:T, 6k4m:U, 6k4m:V, 6k4m:W, 6k4m:X, 5xx9:A, 5xx9:B, 5xx9:C, 5xx9:D, 5xx9:E, 5xx9:F, 7y6f:A, 7y6f:B, 7y6f:C, 7y6f:D, 7y6f:E, 7y6f:F, 7y6f:G, 7y6f:X, 7y6f:H, 7y6f:N, 7y6f:I, 7y6f:J, 7y6f:K, 7y6f:L, 7y6f:M, 7y6f:O, 7y6f:P, 7y6f:Q, 7y6f:R, 7y6f:S, 7y6f:T, 7y6f:U, 7y6f:V, 7y6f:W, 7y6g:A, 7y6g:B, 7y6g:C, 7y6g:D, 7y6g:E, 7y6g:F, 7y6g:G, 7y6g:X, 7y6g:H, 7y6g:N, 7y6g:I, 7y6g:J, 7y6g:K, 7y6g:L, 7y6g:M, 7y6g:O, 7y6g:P, 7y6g:Q, 7y6g:R, 7y6g:S, 7y6g:T, 7y6g:U, 7y6g:V, 7y6g:W, 7y6p:A, 7y6p:B, 7y6p:C, 7y6p:D, 7y6p:E, 7y6p:F, 7y6p:G, 7y6p:X, 7y6p:H, 7y6p:N, 7y6p:I, 7y6p:J, 7y6p:K, 7y6p:L, 7y6p:M, 7y6p:O, 7y6p:P, 7y6p:Q, 7y6p:R, 7y6p:S, 7y6p:T, 7y6p:U, 7y6p:V, 7y6p:W
20 3fvb:A 161 48 0.3750 0.1118 0.3750 0.52 3fvb:B, 8sqo:A, 8sqp:A, 8sqq:A, 8sqr:A, 8sqt:A
21 7ysw:C 213 20 0.1667 0.0376 0.4000 2.8 7ysw:E
22 5ux2:A 220 21 0.1667 0.0364 0.3810 2.9 5ux2:B
23 9bts:A 154 55 0.3125 0.0974 0.2727 3.2 9bts:B, 9bts:C, 9bts:D, 9bts:E, 9bts:F, 9bts:G, 9bts:H
24 5x4j:A 471 25 0.2083 0.0212 0.4000 3.9 5x4h:A, 5x4i:A, 5x4k:A
25 3vte:A 502 13 0.1458 0.0139 0.5385 4.7
26 2icy:B 463 36 0.2083 0.0216 0.2778 4.9 2icx:A, 2icx:B, 2icy:A
27 8i9z:CE 465 16 0.1875 0.0194 0.5625 5.4 8i9p:CE, 8i9r:CE, 8i9t:CE, 8i9v:CE, 8i9w:CE, 8i9x:CE, 8i9y:CE, 8ia0:CE
28 3ctp:A 266 40 0.3333 0.0602 0.4000 5.8 3ctp:B
29 5cqg:A 596 32 0.2500 0.0201 0.3750 7.1 5cqg:B, 6e53:A, 7kqm:A, 7kqn:A, 7kqn:D, 3kyl:A, 6uso:A, 6usp:A, 6usq:A, 6usr:A
30 8ro0:a 81 28 0.2292 0.1358 0.3929 7.9 8ro1:a
31 2iss:B 285 22 0.1875 0.0316 0.4091 8.3 2iss:A, 2iss:C
32 5ini:F 511 15 0.1458 0.0137 0.4667 8.9 5inf:B, 5inf:F, 5ini:A, 5ini:D, 5ini:B, 5ini:C, 5ini:E
33 7pfs:A 916 39 0.3125 0.0164 0.3846 9.9 5ab0:A, 5ab2:A, 5j6s:A, 5k1v:A, 7nsk:A, 7nup:A, 7nup:B, 7p7p:A, 7sh0:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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