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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DQKNKQKLQLIEELTSNADQVQRQVLEEILTRNADVEYLRRHDLNGRTDRETFKNIMPVITYEDIEPEINRIANGDKSPI
LSSKPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMSQFVPGLENGKGMYFLFIKSESKTPGGLPARPVLTS
YYKSSHFKERPYDPYTNYTSPNETILCSDSYQSMYSQMLCGLCQHQEVLRVGAVFASGFIRAIKFLEKHWIELVRDIRTG
TLSSLITDPSVREAVAKILKPSPKLADFVEFECKKSSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTM
YASSECYFGVNLRPLCKPSEVSYTLIPSMAYFEFLPVHRQQELVDLVDVKLGQEYELVVTTYAGLCRYRVGDLLRVTGFK
NKAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCLDGNTPIPPSV
FEDCCLAVEESFNTVYRQGRVSDKSIGPLEIKIVEPGTFDKLMDYAISLGASINQYKTPRCVKFAPIIELLNSRVVDSYF
SPKCPKWVPGHKQ

The query sequence (length=573) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5kod:D 566 571 0.9843 0.9965 0.9877 0.0
2 7vka:A 595 588 0.9127 0.8790 0.8895 0.0 5kod:A, 5kod:B, 5kod:C, 7vka:B
3 4b2g:B 572 579 0.6719 0.6731 0.6649 0.0 4b2g:A
4 7dk8:A 558 564 0.6579 0.6756 0.6684 0.0
5 6e1q:A 569 569 0.5096 0.5132 0.5132 0.0 6avh:A, 6avh:C, 6avh:D
6 4epm:A 554 554 0.4921 0.5090 0.5090 0.0 4eq4:A, 4eq4:B, 4eql:A, 4eql:B, 4l39:A, 4l39:B, 6oms:A, 6oms:B
7 6avh:B 541 564 0.4817 0.5102 0.4894 0.0
8 4ewv:B 492 552 0.4346 0.5061 0.4511 2.70e-156 4ewv:A
9 5ech:A 569 562 0.3962 0.3989 0.4039 2.09e-142 5ech:D, 5eci:A, 5eci:D, 5eck:A, 5eck:D, 5ecl:A, 5ecl:D, 5ecm:A, 5ecm:D, 5ecn:A, 5ecn:D, 5eco:A, 5eco:D, 5ecp:A, 5ecp:D, 5ecq:A, 5ecq:D, 5ecr:A, 5ecr:D, 4epl:A, 5gzz:A
10 4rpu:A 988 81 0.0366 0.0213 0.2593 0.29 4l3t:A, 4l3t:B, 4nge:A, 4nge:D, 4rpu:B
11 6xov:A 966 81 0.0366 0.0217 0.2593 0.31
12 7k7m:B 757 158 0.0628 0.0476 0.2278 1.3 7k7m:A, 7n6b:A
13 6ajf:A 901 158 0.0628 0.0400 0.2278 1.7 6ajg:A, 6ajh:A, 6ajj:A, 7c2m:A, 7c2n:A, 6or2:A, 7wnx:A
14 6aji:A 873 158 0.0628 0.0412 0.2278 1.7
15 6xzd:BP1 712 86 0.0332 0.0267 0.2209 5.3 6xzp:BP1, 6xzq:B, 6xzr:BP1, 6y0c:B
16 8k1l:A 979 64 0.0332 0.0194 0.2969 6.0
17 6o75:A 710 136 0.0541 0.0437 0.2279 8.8 6o74:A, 6o78:A, 6o79:A, 6o7b:A, 6o7d:A
18 6muu:A 780 136 0.0541 0.0397 0.2279 9.6 6iqw:A, 6mur:A, 6mus:A, 6mut:A, 6o7e:A, 6o7h:A
19 5zer:A 354 80 0.0366 0.0593 0.2625 9.7 5zer:B, 5zes:A, 5zfk:A, 5zfk:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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