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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
CVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHDNPVLPFNDGVYFASTEKSNIIRGW
IFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGMESEFRVYSSANNCTFEYVSQPFLNFKNLREFVFKNIDGYFK
IYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSET
KCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKC
YGVCPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKS
NLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCV
NFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTE
VPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTSQSIIAYTMSLGAENSVAYSNNS
IAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKT
PPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIA
QYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDV
VNQNAQALNTLVKQLSSNFGAISSVLNDILSRLCPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSE
CVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYE
PQIITTDNTFVSGNCDVVIGIVNNTVYDP

The query sequence (length=1069) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7jji:A 1109 1115 0.9860 0.9504 0.9453 0.0 8aaa:A, 7b62:A, 7beh:E, 7bem:E, 8bec:B, 8bec:D, 7d2z:B, 7d30:B, 7dwy:A, 7dwy:B, 7dwy:C, 7e7b:A, 7e7b:B, 7e7b:C, 7f5g:C, 8j1q:C, 8j26:C, 7jji:C, 7jji:B, 7kmh:C, 7l2c:B, 7l4z:B, 7l4z:D, 7l4z:A, 7l4z:C, 7l4z:E, 7ldj:A, 7ly3:A, 7ly3:B, 7q0i:D, 8qh0:A, 7qur:A, 7qur:B, 7qur:C, 7qus:A, 7qus:B, 7qus:C, 7r6w:R, 7sn0:C, 7wd8:B, 7wgv:A, 7wgv:B, 7wgv:C, 7wk8:A, 7x08:A, 7x08:B, 7x08:C, 7x2l:E, 7x93:G, 7xtz:A, 7xtz:C, 7xtz:B, 7xu0:C, 7xu0:B, 7xu1:A, 7xu6:A, 7xu6:C, 7xu6:B, 7xwa:D, 7y0c:E, 7y0c:R, 7yck:A, 7z8o:A, 7zbu:A, 6zp2:A, 6zp2:C, 6zp2:B
2 8hlc:A 1081 1091 0.9822 0.9713 0.9624 0.0 7e7d:A, 7e7d:B, 7e7d:C, 8h3e:A, 8h3e:B, 8h3e:C, 8hlc:B, 8hlc:C, 7odl:A, 7odl:B, 7odl:C, 7wgx:A, 7wgx:B, 7wgx:C, 6zb4:C, 6zb4:B, 6zb4:A, 6zoz:A, 6zoz:B, 6zoz:C
3 8cya:A 1100 1114 0.9785 0.9509 0.9390 0.0 7nt9:A, 7nt9:B, 7nt9:C, 7nta:B, 7nta:C, 7nta:A, 7ntc:A, 7ntc:B, 8p9y:C
4 7wuh:E 1044 1086 0.9523 0.9751 0.9374 0.0 7wuh:A, 7xu3:B, 7xu3:A, 7xu3:C, 6zb5:A, 6zb5:C, 6zb5:B
5 8bon:B 1070 1109 0.9504 0.9495 0.9161 0.0 8bon:A, 8bon:C, 7nd7:A, 7nd7:B, 7nd7:C, 8xut:B, 8xut:A
6 7cn8:A 1125 1120 0.9298 0.8836 0.8875 0.0 7cn8:B, 7cn8:C, 7ek6:A, 7xu0:A, 7xu1:C, 7xu1:B, 7xu2:A, 7xu2:C, 7xu2:B, 7xu4:A, 7xu4:C, 7xu4:B
7 7od3:A 1012 1056 0.9429 0.9960 0.9545 0.0 7od3:B, 7od3:C
8 7tei:B 1042 1061 0.9336 0.9578 0.9406 0.0
9 8xus:B 1063 1067 0.9298 0.9351 0.9316 0.0 8if2:B
10 7q9f:A 1009 1059 0.9270 0.9822 0.9358 0.0 7akd:C, 7l56:B, 7l56:C, 7l56:A, 7q9f:B
11 7y42:A 968 1057 0.8952 0.9886 0.9054 0.0 7y42:B, 7y42:D
12 7xu5:B 938 1057 0.8718 0.9936 0.8817 0.0 7xu5:A, 7xu5:C
13 8h3m:C 930 1056 0.8475 0.9742 0.8580 0.0
14 8h0z:B 1045 1053 0.7643 0.7818 0.7759 0.0 8h0x:A, 8h0x:B, 8h0x:C, 8h0y:A, 8h0y:C, 8h0z:C, 8h14:B, 8h14:C, 8h14:A
15 8tc0:B 1091 1101 0.7671 0.7516 0.7448 0.0 8tc0:A, 8tc0:C, 8tc1:C, 8tc1:A, 8tc1:B, 8tc5:C, 8tc5:A, 8tc5:B, 1zv8:A, 1zv8:C, 1zv8:E, 5zvm:A, 5zvm:B
16 8h10:A 1026 1053 0.7493 0.7807 0.7607 0.0 8h0y:B, 8h0z:A, 8h10:B, 8h10:C, 7zh1:A, 7zh1:B, 7zh1:C, 7zh2:A, 7zh2:B, 7zh2:C
17 8xuu:A 431 463 0.3592 0.8910 0.8294 0.0
18 7xog:B 348 231 0.2123 0.6523 0.9827 1.74e-156
19 7xog:B 348 68 0.0636 0.1954 1.0000 2.35e-36
20 6nb3:A 1169 898 0.2909 0.2660 0.3463 3.14e-137 5gmq:A, 6j11:A, 6j11:B, 6j11:C, 7m5e:C, 7m5e:E, 7m5e:A, 6nb4:A, 6pxh:A, 6pxh:B, 6q04:C, 6q04:A, 6q04:B, 6q05:C, 6q05:A, 6q05:B, 6q06:C, 6q06:A, 6q06:B, 6q07:C, 6q07:A, 6q07:B, 7ymt:B, 7ymt:C, 7ymv:A, 7ymv:B, 7ymy:B, 7ymz:B, 7yn0:A, 7yn0:B, 7yn0:C
21 8sak:A 1121 588 0.2236 0.2132 0.4065 5.45e-118
22 8sak:A 1121 165 0.0486 0.0464 0.3152 7.73e-18
23 6vw1:E 193 194 0.1581 0.8756 0.8711 2.33e-117
24 7sbw:B 1196 605 0.2152 0.1923 0.3802 1.03e-113 6nzk:A, 6nzk:B, 6nzk:C, 7sb3:J, 7sb3:A, 7sb3:B, 7sb4:A, 7sb4:C, 7sb4:B, 7sbv:J, 7sbv:A, 7sbv:B, 7sbw:J, 7sbw:A, 7sbx:J, 7sbx:B, 7sbx:A, 7sby:J, 7sby:A, 7sby:B
25 7sbw:B 1196 180 0.0496 0.0443 0.2944 7.25e-19 6nzk:A, 6nzk:B, 6nzk:C, 7sb3:J, 7sb3:A, 7sb3:B, 7sb4:A, 7sb4:C, 7sb4:B, 7sbv:J, 7sbv:A, 7sbv:B, 7sbw:J, 7sbw:A, 7sbx:J, 7sbx:B, 7sbx:A, 7sby:J, 7sby:A, 7sby:B
26 8opo:A 1195 605 0.2021 0.1808 0.3570 2.66e-110 5kwb:A, 8opm:A, 8opm:B, 8opm:C, 8opn:A, 8opn:B, 8opn:C, 8opo:B, 8opo:C, 8y7y:A
27 8opo:A 1195 173 0.0486 0.0435 0.3006 3.41e-17 5kwb:A, 8opm:A, 8opm:B, 8opm:C, 8opn:A, 8opn:B, 8opn:C, 8opo:B, 8opo:C, 8y7y:A
28 7y6t:C 1098 603 0.1852 0.1803 0.3284 8.90e-81
29 7y6t:A 1124 620 0.1871 0.1779 0.3226 1.09e-80
30 8fr7:A 1275 658 0.1964 0.1647 0.3191 1.31e-80 8fr7:C, 8fr7:B
31 7w6m:A 1224 620 0.1852 0.1618 0.3194 7.40e-78 7w6m:C, 7w6m:B, 7w73:C, 7w73:A, 7y6t:B, 7y6u:A
32 6vv5:A 1097 628 0.1862 0.1814 0.3169 4.23e-77 6vv5:B, 6vv5:C
33 6u7k:A 1064 614 0.1852 0.1861 0.3225 1.14e-76
34 6lxt:E 114 70 0.0655 0.6140 1.0000 3.06e-37
35 7c53:E 93 70 0.0580 0.6667 0.8857 5.74e-32
36 8wku:B 208 111 0.0290 0.1490 0.2793 0.003
37 8y8b:A 271 28 0.0131 0.0517 0.5000 0.52 8y8j:A
38 1ft9:A 210 107 0.0281 0.1429 0.2804 2.6 1ft9:B, 4k8f:A, 4k8f:B, 4k8f:C, 4k8f:D
39 4ovt:A 301 79 0.0215 0.0764 0.2911 3.0 4ovt:B
40 5kvu:A 738 89 0.0225 0.0325 0.2697 4.5 5kvu:B, 5kvu:C, 5kvu:D
41 8cvt:n 205 121 0.0299 0.1561 0.2645 5.9 5a0q:H, 5a0q:V, 8cvr:H, 8cvr:V, 8cvs:N, 8cvs:b, 8cvt:N, 5lez:N, 5lez:b, 5lf0:N, 5lf0:b, 5lf1:N, 5lf1:b, 5lf3:N, 5lf3:b, 5lf4:N, 5lf4:b, 5lf7:N, 5lf7:b, 4r67:H, 4r67:V, 4r67:j, 3unb:N, 3unb:b, 3unb:p, 3unb:4, 8ypk:A, 8ypk:F, 8yvp:F, 8yvp:A
42 4zlh:B 338 116 0.0225 0.0710 0.2069 6.3 8v24:A, 8v24:C, 7wzb:B, 7wzb:A, 4zlh:A
43 6o8c:A 636 45 0.0168 0.0283 0.4000 6.7 4iwo:A, 4iwp:A, 4iwq:A, 6rsr:A, 6rst:A, 6rsu:A
44 3at5:A 141 71 0.0196 0.1489 0.2958 8.1 3at6:A
45 5wlq:A 104 55 0.0140 0.1442 0.2727 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218