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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
CTYQPRQYIAPFDRQPEGRVPGIPQYFASTLTLGGYGTGVLVRSNEGRPTKVEGNPRHPASLGGTDLFAQAEILTMYDPD
RSTTVLRQGVPSTWAEFTTTLGNALTAARATQGAGVRLLTTTITSPSLAAQIEQFLQAYPQARWYQYEPINRDNVVAGAR
LAFGRDVTTRYDLSAAQVVVSLDADFLAPGPGFVAYARAFAERRKVRKDSTTMNRLYVVEASPSTTGTAADHRLPLRADA
IAAFTGALANELGVGGAPATLSPKAEEFLRAIARDLEEHRGQSVVIAGDQQPPIVHALAHLINAELGNVGQTVFYHEPVE
ARPTNQTEELVALVSEMAAGRVETLIMIGGNPVYNAPGDLRFADRMASVPLTIHLSQFVDETSARATWHIPQAHPLESWG
DARAFDGTASIVQPLIEPLYGGKTANELLAAMLGQPEAESYDLVRSFWLEQIGETGWQVALANGVIAETVAPVIEPTLNE
GAIRATPIPQPGDGVEIVFRPDPSLFDGFYANNGWLQELPRPLTKLVWDNAALMSPRTAIKLLGLPFNADRLIGTEADDR
ERQQYLEQLSKVNGTIARIEYRGGIIEIPIWLLPGHAEDSITLNLGYGRTHAGRVGNNVGIDVYPIRTSDSPWFGAGARV
TNTGRTYLLVSTQDHWTLEGRDIYRVGEFKKFKEDPKYIAKEVYQEEYGRETPNYQSLQPGDDYTGRNAWGMTINLNACI
GCNACVVACQAENNIAVVGKDQVSRGREMHWIRIDRYFAGEDLDNPSIYMMPVNCMQCEKAPCEVVCPVAATVHDYEGLN
NMVYNRCVGTKYCSNNCPYKVRRFNFLQYSDTTTETFKLAFNPDVTVRIRGVMEKCTYCVQRISGARIAAKRAAVQAGQS
SYVISDGAIQTACEQACPTGAIVFGDINDSNSRVAKWKAEGHNYGLLGFLNTVPRTTYLARVRNPSEELEK

The query sequence (length=951) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8k9e:B 951 951 1.0000 1.0000 1.0000 0.0 8k9f:B, 8x2j:B
2 6lod:B 929 969 0.5331 0.5457 0.5232 0.0 6loe:B
3 6f0k:B 961 989 0.4690 0.4641 0.4510 0.0
4 6btm:B 948 995 0.3291 0.3302 0.3146 2.02e-140
5 6cz7:B 234 232 0.0705 0.2863 0.2888 1.44e-21 6cz7:D, 6cz8:D, 6cz8:B, 6cz9:B, 6cz9:D, 6cza:B, 6cza:D
6 2vpw:F 193 207 0.0599 0.2953 0.2754 2.10e-18 2vpw:B, 2vpx:F, 2vpx:B, 2vpy:F, 2vpy:B, 2vpz:F, 2vpz:B
7 1kqf:B 289 226 0.0641 0.2111 0.2699 7.70e-13 1kqg:B
8 7qv7:B 183 152 0.0515 0.2678 0.3224 9.06e-10 7qv7:C, 7qv7:J, 7qv7:N, 7qv7:P, 7qv7:X
9 7qv7:A 174 199 0.0536 0.2931 0.2563 2.68e-07 7qv7:G
10 7qv7:A 174 101 0.0273 0.1494 0.2574 4.1 7qv7:G
11 7z0s:B 170 107 0.0326 0.1824 0.2897 1.10e-06 7z0t:B
12 8c0z:C 158 213 0.0568 0.3418 0.2535 1.14e-06 8c0z:F
13 4v4c:B 274 114 0.0358 0.1241 0.2982 2.09e-06 4v4c:D, 4v4c:F, 4v4c:H, 4v4c:J, 4v4c:L, 4v4c:N, 4v4c:P, 4v4c:R, 4v4c:T, 4v4c:V, 4v4c:X, 4v4d:B, 4v4d:D, 4v4d:F, 4v4d:H, 4v4d:J, 4v4d:L, 4v4d:N, 4v4d:P, 4v4d:R, 4v4d:T, 4v4d:V, 4v4d:X, 4v4e:B, 4v4e:D, 4v4e:F, 4v4e:H, 4v4e:J, 4v4e:L, 4v4e:N, 4v4e:P, 4v4e:R, 4v4e:T, 4v4e:V, 4v4e:X
14 2ivf:B 337 181 0.0463 0.1306 0.2431 6.11e-06
15 2ivf:B 337 17 0.0105 0.0297 0.5882 4.1
16 6x6u:B 167 112 0.0358 0.2036 0.3036 4.03e-04 6x1o:B, 6x1o:D, 6x6u:D
17 1h0h:B 214 225 0.0536 0.2383 0.2267 0.002 1h0h:L
18 3egw:B 509 106 0.0263 0.0491 0.2358 0.008 3ir5:B, 3ir6:B, 3ir7:B, 1q16:B, 1r27:B, 1r27:D, 1siw:B, 1y4z:B, 1y5i:B, 1y5l:B, 1y5n:B
19 3egw:B 509 24 0.0116 0.0216 0.4583 3.7 3ir5:B, 3ir6:B, 3ir7:B, 1q16:B, 1r27:B, 1r27:D, 1siw:B, 1y4z:B, 1y5i:B, 1y5l:B, 1y5n:B
20 7vw6:A 913 116 0.0347 0.0361 0.2845 0.014 7e5z:A, 8j83:A, 7xqw:A
21 5ch7:B 329 70 0.0242 0.0699 0.3286 0.014 5ch7:D, 5ch7:F, 5chc:B, 5chc:D, 5chc:F, 5e7o:B, 5e7o:D, 5e7o:F, 5e7o:H, 5e7o:J, 5e7o:L, 4ydd:B, 4ydd:D, 4ydd:F
22 5ch7:B 329 16 0.0105 0.0304 0.6250 9.0 5ch7:D, 5ch7:F, 5chc:B, 5chc:D, 5chc:F, 5e7o:B, 5e7o:D, 5e7o:F, 5e7o:H, 5e7o:J, 5e7o:L, 4ydd:B, 4ydd:D, 4ydd:F
23 1a6l:A 106 52 0.0179 0.1604 0.3269 0.044 1axq:A, 1b0t:A, 1b0v:A, 1b0v:B, 1b0v:C, 1b0v:D, 1d3w:A, 1f5b:A, 1f5c:A, 1fd2:A, 1fda:A, 1fdb:A, 1fdd:A, 2fd2:A, 5fd1:A, 6fd1:A, 6fdr:A, 7fd1:A, 7fdr:A, 1fer:A, 1ff2:A, 1frh:A, 1fri:A, 1frj:A, 1frk:A, 1frl:A, 1frm:A, 1frx:A, 1ftc:A, 1ftc:B, 1g3o:A, 1g6b:A, 1gao:A, 1gao:B, 1gao:C, 1gao:D, 1pc4:A, 1pc5:A
24 6u8y:N 176 94 0.0252 0.1364 0.2553 0.12 6u8y:n
25 7bkb:L 79 21 0.0116 0.1392 0.5238 0.13 7bkb:l, 7bkc:L, 7bkc:l
26 8rbq:C 477 68 0.0189 0.0377 0.2647 0.40 8ahx:C, 8rb8:C, 8rb9:C, 8rbm:C
27 1bc6:A 77 42 0.0168 0.2078 0.3810 0.52 1bd6:A, 1bqx:A, 1bwe:A
28 5hje:A 676 91 0.0273 0.0385 0.2857 0.65 5hyv:A, 5i51:A, 5i5e:A, 5i5g:A, 5xps:A, 5xqa:A, 5xqk:A, 5xrv:A, 5xry:A, 5xs6:A, 5xsa:A, 5xsb:A, 5xsm:A, 5xt0:A, 5xt4:A, 5xtl:A, 5xtv:A, 5xtx:A, 5xu2:A, 5xu9:A, 5xuf:A, 5xvt:A
29 7b04:A 409 144 0.0358 0.0831 0.2361 1.1 7b04:D, 7b04:G, 7b04:J, 7b04:M, 7b04:P, 7b04:S, 7b04:V
30 6cfw:N 121 53 0.0126 0.0992 0.2264 1.7
31 8a6t:B 630 47 0.0158 0.0238 0.3191 1.9 8a6t:E, 8bew:B, 8bew:E
32 7bkc:K 321 56 0.0189 0.0561 0.3214 2.2 7bkc:k
33 7zc6:B 202 110 0.0294 0.1386 0.2545 2.3
34 7z0s:F 164 77 0.0252 0.1463 0.3117 3.0 7z0t:F
35 7bkb:K 386 56 0.0189 0.0466 0.3214 3.6 7bkb:k, 7bkc:M, 7bkc:m
36 6a2d:A 519 61 0.0231 0.0424 0.3607 4.0 6a2c:A, 6a2c:B, 6a2d:B
37 4wgk:B 672 88 0.0210 0.0298 0.2273 4.1 4wgk:A
38 3mm5:A 417 123 0.0294 0.0671 0.2276 4.3 3mm5:D, 3mm6:A, 3mm6:D, 3mm7:A, 3mm7:D, 3mm8:A, 3mm8:D, 3mm9:A, 3mm9:D, 3mma:A, 3mma:D, 3mmb:A, 3mmb:D, 3mmc:A, 3mmc:D
39 5imr:C 570 98 0.0294 0.0491 0.2857 4.4
40 4hea:9 180 13 0.0116 0.0611 0.8462 4.6 2fug:9, 2fug:G, 2fug:P, 2fug:Y, 4hea:O, 6i0d:9, 6i0d:O, 6i1p:9, 6i1p:O, 3i9v:9, 3i9v:G, 3iam:9, 3iam:G, 3ias:9, 3ias:G, 3ias:P, 3ias:Y, 3m9s:9, 3m9s:G, 6q8o:9, 6q8o:O, 6q8w:9, 6q8w:O, 6q8x:9, 6q8x:O, 6y11:9, 6y11:O, 2ybb:8, 6ziy:9, 6zjl:9, 6zjn:9, 6zjy:9
41 8bqg:B 214 254 0.0599 0.2664 0.2244 5.5 8bqh:B, 8bqi:B, 8bqj:B, 8bqk:B, 8bql:B, 8cm4:B, 8cm4:D, 8cm5:B, 8cm5:D, 8cm5:L, 8cm5:S, 8cm6:B, 8cm6:D, 8cm7:B, 8rc8:B, 8rc9:B, 8rca:B, 8rcb:B, 8rcc:B, 8rcg:B, 6sdr:B, 6sdv:B, 7z5o:BBB
42 7z6q:B 123 37 0.0126 0.0976 0.3243 6.2 8gwa:B, 6m32:B
43 1b0p:A 1231 72 0.0189 0.0146 0.2500 6.4 1b0p:B, 2c3m:A, 2c3m:B, 2c3o:A, 2c3o:B, 2c3p:A, 2c3p:B, 2c3u:A, 2c3u:B, 2c3y:A, 2c3y:B, 2c42:A, 2c42:B, 1kek:A, 1kek:B, 2pda:A, 2pda:B, 2uza:A, 2uza:B
44 7ueb:B 114 37 0.0126 0.1053 0.3243 6.4 7uea:B
45 4amq:A 341 83 0.0221 0.0616 0.2530 6.4
46 4dhv:B 66 21 0.0084 0.1212 0.3810 6.6 4dhv:A, 3pni:A, 3pni:B, 1siz:A, 1siz:C, 1sj1:A, 1sj1:B, 2z8q:A, 2z8q:B
47 6h8k:I 137 50 0.0147 0.1022 0.2800 6.7
48 6a1i:A 522 71 0.0242 0.0441 0.3239 7.7 6a1d:A, 6a1e:A, 6a3x:A, 7e9r:B, 7e9r:C, 6k16:A, 6o9p:A
49 3waj:A 793 111 0.0347 0.0416 0.2973 8.8
50 7e9s:A 867 111 0.0347 0.0381 0.2973 8.8 5gmy:A, 3wak:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218