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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
CQFALKQPQEKIVPYVRQPEEIIHGRPLFFATAVTFAGFGVGLLVESHEGRPTKIEGNPDHPASLGSTDLITQAMILTMY
DPDRSQAPTNAGQETTWDAFVAAATAAMQAQTAKQGAGLRVLSGSLTSPTLIAQKQQLLTQFPQAKWYEYEPVGRDNANA
GARLAFGADVHTIYRLDTAKVIVGFDADFTAPSPTGVRMARQLADGRRIRKGTKEVNRLYLAESTPSITGLLADHRLPVR
SSQIEHLVRALATLVGVPNVAAGAPLSDTEKKWVEAAAKDLQANRGACVVLVGESQPPVVHALGHAINAQLGNVGSTVVY
TEPVEDDPSGGIAALSALTQEMNAGTVEVLLMIESNPVYNAPADIPFAEALAKVPLSMHVGLYRDETAQQSVWHINGAHF
LEAWGDVRAFDGTTTIVQPLIAPLYNGKSAIEVLNVLLGKPQETGYQTLTAYWQTQDASGNFRVFWNTALHDGVITATQA
RSRQVTLQQGFADAAPPAPTQGLEIVFRPDPSLWDGAFANNAWLQETPKPYTKLTWDNVALMSVRTANALGLKNGDVVRL
TYQGRSVDAPVWVQPGHADDSVTVHFGFGRTAAGRVGNNVGFNAYRLRTSATPWFGVGLEVAKVGENYKLASTQGHFLME
GRKKDLVRYGTLAEYVEDEKFLQVEKEEPISLIGEYEYNGYKWGMSIDLNVCNSCNACVVACQSENNIPVVGKDEVWLGR
EMHWIRIDQYYVGDEHTPNVYNMVMLCQQCEHAPCEIVCPVAATVHDAEGLNNMVYNRCVGTKYCSNNCPYKVRRFNFLQ
YQDVPYRSPIDASTENDSIPVLKMMRNPDVTVRARGVMEKCTFCVQRINEARIQARTENRRIADGEIMTACQQVCPTQAI
VFGDLNDPQARVVDLKEQPLKYTSLDKLNTKPRVSYLAKIKNLNPDLAE

The query sequence (length=929) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6lod:B 929 929 1.0000 1.0000 1.0000 0.0 6loe:B
2 8k9e:B 951 969 0.5457 0.5331 0.5232 0.0 8k9f:B, 8x2j:B
3 6f0k:B 961 987 0.4898 0.4735 0.4610 0.0
4 6btm:B 948 975 0.3595 0.3523 0.3426 1.85e-148
5 6cz7:B 234 258 0.0850 0.3376 0.3062 2.92e-24 6cz7:D, 6cz8:D, 6cz8:B, 6cz9:B, 6cz9:D, 6cza:B, 6cza:D
6 2vpw:F 193 237 0.0689 0.3316 0.2700 1.41e-16 2vpw:B, 2vpx:F, 2vpx:B, 2vpy:F, 2vpy:B, 2vpz:F, 2vpz:B
7 7z0s:B 170 199 0.0506 0.2765 0.2362 1.43e-06 7z0t:B
8 1kqf:B 289 234 0.0592 0.1903 0.2350 1.69e-05 1kqg:B
9 7qv7:B 183 175 0.0527 0.2678 0.2800 2.49e-05 7qv7:C, 7qv7:J, 7qv7:N, 7qv7:P, 7qv7:X
10 2ivf:B 337 159 0.0388 0.1068 0.2264 4.64e-05
11 7qv7:A 174 144 0.0452 0.2414 0.2917 0.001 7qv7:G
12 8c0z:C 158 114 0.0355 0.2089 0.2895 0.002 8c0z:F
13 4v4c:B 274 145 0.0366 0.1241 0.2345 0.005 4v4c:D, 4v4c:F, 4v4c:H, 4v4c:J, 4v4c:L, 4v4c:N, 4v4c:P, 4v4c:R, 4v4c:T, 4v4c:V, 4v4c:X, 4v4d:B, 4v4d:D, 4v4d:F, 4v4d:H, 4v4d:J, 4v4d:L, 4v4d:N, 4v4d:P, 4v4d:R, 4v4d:T, 4v4d:V, 4v4d:X, 4v4e:B, 4v4e:D, 4v4e:F, 4v4e:H, 4v4e:J, 4v4e:L, 4v4e:N, 4v4e:P, 4v4e:R, 4v4e:T, 4v4e:V, 4v4e:X
14 6x6u:B 167 105 0.0312 0.1737 0.2762 0.008 6x1o:B, 6x1o:D, 6x6u:D
15 7b04:A 409 193 0.0484 0.1100 0.2332 0.010 7b04:D, 7b04:G, 7b04:J, 7b04:M, 7b04:P, 7b04:S, 7b04:V
16 3egw:B 509 63 0.0205 0.0373 0.3016 0.014 3ir5:B, 3ir6:B, 3ir7:B, 1q16:B, 1r27:B, 1r27:D, 1siw:B, 1y4z:B, 1y5i:B, 1y5l:B, 1y5n:B
17 1h0h:B 214 220 0.0484 0.2103 0.2045 0.17 1h0h:L
18 2nya:A 791 53 0.0194 0.0228 0.3396 0.17 2nya:F
19 5ch7:B 329 68 0.0183 0.0517 0.2500 0.95 5ch7:D, 5ch7:F, 5chc:B, 5chc:D, 5chc:F, 5e7o:B, 5e7o:D, 5e7o:F, 5e7o:H, 5e7o:J, 5e7o:L, 4ydd:B, 4ydd:D, 4ydd:F
20 1orb:A 293 68 0.0248 0.0785 0.3382 1.1
21 7vw6:A 913 114 0.0334 0.0340 0.2719 1.1 7e5z:A, 8j83:A, 7xqw:A
22 8wm6:C 80 57 0.0183 0.2125 0.2982 1.2 8wmj:C, 8wmv:C, 8wmw:C, 7y5e:CN, 7y5e:C2, 7y7a:C7, 7y7a:Co, 7y7b:C, 7y8a:C
23 3bk7:A 593 49 0.0172 0.0270 0.3265 1.2 3j15:B, 5lw7:B, 1yqt:A, 5yv5:A
24 2vpw:A 734 296 0.0700 0.0886 0.2196 2.5 2vpw:E, 2vpx:A, 2vpx:E, 2vpy:A, 2vpy:E, 2vpz:A, 2vpz:E
25 1bc6:A 77 40 0.0172 0.2078 0.4000 3.2 1bd6:A, 1bqx:A, 1bwe:A
26 8cm5:A 974 35 0.0151 0.0144 0.4000 3.2 8bqg:A, 8bqh:A, 8bqi:A, 8bqj:A, 8bqk:A, 8bql:A, 8cm4:A, 8cm4:C, 8cm5:C, 8cm5:K, 8cm5:R, 8cm6:A, 8cm6:C, 8cm7:A, 8rc8:A, 8rc9:A, 8rca:A, 8rcb:A, 8rcc:A, 8rcg:A, 6sdr:A, 6sdv:A, 7z5o:AAA
27 7bkc:K 321 136 0.0398 0.1153 0.2721 3.9 7bkc:k
28 6h8k:I 137 42 0.0140 0.0949 0.3095 4.9
29 3wyc:A 327 43 0.0151 0.0428 0.3256 5.2 5gz3:A, 5gz3:B, 5gz6:A, 3wyc:B
30 7ueb:B 114 43 0.0161 0.1316 0.3488 5.3 7uea:B
31 7z6q:B 123 43 0.0161 0.1220 0.3488 6.0 8gwa:B, 6m32:B
32 1a6l:A 106 46 0.0161 0.1415 0.3261 8.8 1axq:A, 1b0t:A, 1b0v:A, 1b0v:B, 1b0v:C, 1b0v:D, 1d3w:A, 1f5b:A, 1f5c:A, 1fd2:A, 1fda:A, 1fdb:A, 1fdd:A, 2fd2:A, 5fd1:A, 6fd1:A, 6fdr:A, 7fd1:A, 7fdr:A, 1fer:A, 1ff2:A, 1frh:A, 1fri:A, 1frj:A, 1frk:A, 1frl:A, 1frm:A, 1frx:A, 1ftc:A, 1ftc:B, 1g3o:A, 1g6b:A, 1gao:A, 1gao:B, 1gao:C, 1gao:D, 1pc4:A, 1pc5:A
33 7bkb:K 386 199 0.0463 0.1114 0.2161 9.2 7bkb:k, 7bkc:M, 7bkc:m

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218