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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
CGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDL
DIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYD
NRESQDTSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRSRVDSTTCLFPVEE
KAVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVN
TMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCF
FLSQSGETADTLMGLRYCKERGALTVGITNTVESSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRIS
MQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHG
PLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAF
HLAVLRGYDVDFPRNLAKSVTVE

The query sequence (length=663) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6r4e:A 663 664 0.9970 0.9970 0.9955 0.0 7ndl:A, 7ndl:B, 6r4e:B, 6r4f:A, 6r4f:B, 6r4g:A, 6r4g:B, 6r4h:A, 6r4h:B, 6r4i:A, 6r4i:B, 6r4j:A, 6r4j:B, 6svm:A, 6svm:B, 6svo:A, 6svo:B, 6svp:A, 6svp:B, 6svq:A, 6svq:B, 2v4m:A, 2v4m:B, 2v4m:C, 2v4m:D, 2zj3:A, 2zj4:A, 6zmj:A, 6zmj:B, 6zmk:A, 6zmk:B
2 2poc:B 352 352 0.3318 0.6250 0.6250 2.48e-151 2poc:A, 2poc:C, 2poc:D, 2put:A, 2put:B, 2put:C, 2put:D, 2puv:A, 2puv:B, 2puv:C, 2puv:D, 2puw:A
3 2puw:B 331 349 0.3152 0.6314 0.5989 2.37e-142
4 4amv:A 608 671 0.3937 0.4293 0.3890 3.31e-140 4amv:B, 4amv:C, 7dnr:A, 2j6h:A, 2j6h:B, 1jxa:A, 1jxa:B, 1moq:A, 1mor:A, 1mos:A, 3ooj:A, 3ooj:B, 3ooj:C, 3ooj:D, 3ooj:E, 3ooj:F, 3ooj:G, 3ooj:H, 2vf5:X, 1xff:A, 1xff:B, 1xfg:A, 1xfg:B
5 8fdb:B 333 279 0.1101 0.2192 0.2616 3.58e-24 8eym:A, 8eym:B, 8fdb:A
6 2df8:A 325 321 0.1131 0.2308 0.2336 1.48e-11 2df8:B
7 1gph:1 465 190 0.0754 0.1075 0.2632 3.31e-09 1ao0:A, 1ao0:B, 1ao0:C, 1ao0:D, 1gph:2, 1gph:3, 1gph:4
8 1ecf:B 500 143 0.0588 0.0780 0.2727 2.61e-06 6czf:A, 6czf:C, 6czf:B, 6czf:D, 1ecb:A, 1ecb:B, 1ecb:C, 1ecb:D, 1ecc:A, 1ecc:B, 1ecf:A, 1ecg:A, 1ecg:B, 1ecj:A, 1ecj:C, 6ott:A, 6ott:B, 8w7d:A, 8w7d:B, 8w7d:C, 8w7d:D
9 6lbp:A 460 164 0.0664 0.0957 0.2683 3.69e-06 6lbp:B
10 4lzj:B 299 78 0.0392 0.0870 0.3333 4.47e-05 4lzj:C, 4lzj:D, 4lzj:A
11 5uqi:A 188 144 0.0588 0.2074 0.2708 7.49e-04
12 3tgw:B 441 116 0.0528 0.0794 0.3017 0.11 3b2q:A, 3b2q:B, 3dsr:A, 3dsr:B, 3eiu:A, 3eiu:B, 3tiv:B
13 7mfm:G 1483 88 0.0317 0.0142 0.2386 0.89 7mfm:H, 7mft:G
14 2xcu:A 353 45 0.0241 0.0453 0.3556 1.9 2xcu:B, 2xcu:C, 2xcu:D
15 5w21:A 922 42 0.0226 0.0163 0.3571 3.8 7ysh:A, 7ysu:A, 7ysw:A
16 6yw5:FF 117 43 0.0121 0.0684 0.1860 6.6 6ywe:FF, 6ywx:FF, 6ywy:FF
17 4yrb:B 215 48 0.0211 0.0651 0.2917 7.0 4yrb:F
18 4rk1:D 269 37 0.0166 0.0409 0.2973 8.2 4rk1:A, 4rk1:B, 4rk1:C, 4rk1:E, 4rk1:F
19 8d8k:T 92 20 0.0151 0.1087 0.5000 9.7 8d8l:T, 5mrc:TT, 5mre:TT, 5mrf:TT, 8om2:T, 8om3:T, 8om4:T

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218