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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AVYTLPELPYDYSALEPYISGEIMELHHDKHHKAYVDGANTALDKLAEARDKADFGAINKLEKDLAFNLAGHVNHSVFWK
NMAPKGSAPERPTDELGAAIDEFFGSFDNMKAQFTAAATGIQGSGWASLVWDPLGKRINTLQFYDHQNNLPAGSIPLLQL
DMWEHAFYLQYKNVKGDYVKSWWNVVNWDDVALRFSEARVA

The query sequence (length=201) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1ar4:A 201 201 1.0000 1.0000 1.0000 1.02e-150 1ar4:B, 1ar5:A, 1ar5:B, 1avm:A, 1avm:B, 1bs3:A, 1bs3:B, 1bsm:A, 1bsm:B, 1bt8:A, 1bt8:B
2 8bhx:A 203 199 0.7164 0.7094 0.7236 9.01e-104 8bhx:B
3 1gn2:A 198 198 0.6169 0.6263 0.6263 7.14e-87 1gn2:B, 1gn2:C, 1gn2:D, 1gn2:E, 1gn2:F, 1gn2:G, 1gn2:H, 1gn3:A, 1gn3:B, 1gn4:A, 1gn4:B, 1gn4:C, 1gn4:D, 1gn6:A, 1gn6:B, 1gn6:C, 1gn6:D, 1ids:A, 1ids:B, 1ids:C, 1ids:D
4 3evk:A 211 196 0.5075 0.4834 0.5204 4.07e-67 3evk:B, 3evk:C, 3evk:D
5 3ak3:B 213 196 0.4726 0.4460 0.4847 1.23e-64 3ak2:A, 3ak2:B, 3ak2:C, 3ak2:D, 3ak3:A, 3ak3:C, 3ak3:D
6 7kks:A 199 201 0.4826 0.4874 0.4826 1.85e-62 2adp:A, 2adq:B, 1ap5:A, 1ap5:B, 1ap6:A, 1ap6:B, 3c3s:A, 3c3s:B, 3c3t:A, 3c3t:B, 1em1:A, 1em1:B, 2gds:A, 2gds:B, 2gds:C, 2gds:D, 5gxo:A, 5gxo:B, 1ja8:A, 1ja8:B, 7kks:B, 7kku:A, 7kku:B, 7kkw:A, 7kkw:B, 7klb:A, 7klb:B, 1luv:A, 1luv:B, 1luw:A, 1luw:B, 1msd:A, 1msd:B, 1n0j:A, 1n0j:B, 1n0n:A, 1n0n:B, 2p4k:A, 2p4k:B, 2p4k:C, 2p4k:D, 1pl4:A, 1pl4:B, 1pl4:C, 1pl4:D, 1pm9:A, 1pm9:B, 2qka:A, 2qka:C, 2qkc:A, 2qkc:C, 1qnm:A, 1qnm:B, 8sks:A, 8sks:B, 8sks:C, 8sks:D, 1szx:A, 1szx:B, 5t30:A, 5t30:B, 1var:A, 1var:B, 5vf9:A, 5vf9:B, 8vhw:A, 8vhw:B, 8vhy:A, 8vhy:B, 8vj0:A, 8vj0:B, 8vj4:A, 8vj4:B, 8vj5:A, 8vj5:B, 8vj8:A, 8vj8:B, 1xdc:A, 1xdc:B, 1xil:A, 1xil:B, 1zsp:A, 1zsp:B, 1zte:A, 1zte:B, 1zte:C, 1zte:D, 1zuq:A, 1zuq:B
7 4c7u:A 203 193 0.4677 0.4631 0.4870 1.35e-60 4c7u:B, 4c7u:C, 4c7u:D, 4c7u:E, 4c7u:F, 4c7u:G, 4c7u:H
8 3dc6:C 198 199 0.4577 0.4646 0.4623 1.25e-58 3dc6:A
9 1ma1:A 201 195 0.4378 0.4378 0.4513 5.73e-58 1ma1:B, 1ma1:C, 1ma1:D, 1ma1:E, 1ma1:F
10 4ffk:A 212 197 0.4527 0.4292 0.4619 6.80e-57
11 1kkc:A 200 196 0.4577 0.4600 0.4694 6.99e-56 1kkc:B, 1kkc:X, 1kkc:Y
12 5ag2:C 195 198 0.4328 0.4462 0.4394 2.55e-55 5ag2:A, 3dc5:A, 3dc5:C, 6elk:A, 6elk:C, 6qzm:A, 6qzm:C, 6qzn:A, 6qzn:C, 6s0d:A, 6s0d:C, 4x9q:A, 4x9q:C
13 4br6:B 197 198 0.4826 0.4924 0.4899 4.24e-55 4br6:A, 4br6:C, 4br6:D
14 4e4e:B 207 206 0.4279 0.4155 0.4175 7.27e-54 3bfr:A, 4e4e:A, 4e4e:C, 4e4e:D, 4f6e:A, 4f6e:B, 4f6e:C, 4f6e:D, 3lsu:A, 3lsu:B, 3lsu:C, 3lsu:D, 3rn4:A
15 4yio:A 202 200 0.4328 0.4307 0.4350 5.07e-51 4yio:B
16 6cyp:A 211 201 0.4328 0.4123 0.4328 3.34e-50 6cyl:A, 6cyl:B, 6cyl:C, 6cyl:D, 6cyp:B, 6cyp:C, 6cyp:D, 6cyp:E, 6cyp:F, 6cys:A, 6cys:B, 6cys:C, 6cys:D, 6cyx:A, 6cyx:B, 6cyx:C, 6cyx:D, 6cyx:E, 6cyx:F, 6dqy:A, 6dqy:B, 6dqy:C, 6dqy:D, 6dqy:E, 6dqy:F, 6dqy:G, 6dqy:H, 6dqy:I, 6dqy:J, 6dqy:K, 6dqy:L, 6dqy:M, 6dqy:N, 6dqy:O, 6dqy:P, 6dqy:Q, 6dqy:R, 6dqy:S, 6dqy:T, 6dqy:U, 6dqy:V, 6dqy:W, 6dqy:X, 7svs:A, 7svs:B, 7svs:C, 7svs:D, 7svs:E, 7svs:F, 7svs:G, 7svs:H, 5tir:A, 5tir:B, 5tir:C, 5tir:D
17 1wb7:A 205 191 0.4179 0.4098 0.4398 1.81e-49 1wb7:B, 1wb8:A, 1wb8:B
18 6pro:A 202 205 0.4328 0.4307 0.4244 2.11e-49 6pro:B
19 3mds:A 203 203 0.4279 0.4236 0.4236 1.18e-48 3mds:B, 1mng:A, 1mng:B
20 1gv3:A 213 197 0.4030 0.3803 0.4112 1.47e-48 1gv3:B
21 1jr9:A 201 203 0.4378 0.4378 0.4335 3.48e-48
22 8kb3:A 206 210 0.4478 0.4369 0.4286 5.53e-48 1d5n:A, 1d5n:B, 1d5n:C, 1d5n:D, 1en4:A, 1en4:B, 1en4:C, 1en4:D, 1en5:A, 1en5:B, 1en5:C, 1en5:D, 1en6:A, 1en6:B, 1en6:C, 1en6:D, 1i08:A, 1i08:B, 1i08:C, 1i08:D, 1i0h:A, 1i0h:B, 1ix9:A, 1ix9:B, 3k9s:A, 3k9s:B, 3k9s:C, 3k9s:D, 8kb3:B, 1mmm:A, 1mmm:B, 1vew:A, 1vew:B, 1vew:C, 1vew:D, 1zlz:B
23 1b06:A 208 199 0.4179 0.4038 0.4221 6.05e-48 1b06:B, 1b06:C, 1b06:D, 1b06:E, 1b06:F
24 4yip:A 203 200 0.4627 0.4581 0.4650 9.29e-48 4yip:B, 4yip:C, 4yip:D
25 8avk:A 202 201 0.3980 0.3960 0.3980 1.01e-47 8avk:B, 8avn:A, 8avn:B
26 2rcv:A 200 202 0.4279 0.4300 0.4257 1.92e-47 2rcv:B, 2rcv:C, 2rcv:D, 2rcv:E, 2rcv:F, 2rcv:G, 2rcv:H
27 4gun:A 205 197 0.4030 0.3951 0.4112 3.83e-47 4gun:B, 4gun:C, 4gun:D, 4gun:E, 4gun:F, 4gun:G, 4gun:H, 4gun:I, 4gun:J, 4gun:K, 4gun:L, 4gun:M, 4gun:N, 4gun:O, 4gun:P, 3qvn:A
28 1xre:A 201 203 0.3881 0.3881 0.3842 1.42e-46 1xre:B
29 1y67:D 214 212 0.4279 0.4019 0.4057 4.16e-46 2aw9:A, 2aw9:B, 2cdy:A, 2cdy:B, 2cdy:C, 2cdy:D, 2ce4:A, 2ce4:B, 3kky:A, 3kky:B, 1y67:A, 1y67:B, 1y67:C
30 6bej:E 201 204 0.4129 0.4129 0.4069 7.15e-45 6bej:A
31 3tqj:A 192 200 0.4129 0.4323 0.4150 9.63e-44 3tqj:B
32 2cw2:A 199 199 0.3881 0.3920 0.3920 1.01e-43 2cw2:B
33 1xuq:A 200 203 0.3881 0.3900 0.3842 1.53e-43 1xuq:B
34 4jyy:A 202 194 0.3831 0.3812 0.3969 9.48e-42 4jz2:A, 4jzg:A, 3tjt:A
35 3esf:A 197 198 0.3881 0.3959 0.3939 8.62e-40 3esf:B, 3esf:C, 3esf:D
36 6ex4:A 198 206 0.3781 0.3838 0.3689 3.14e-39 6ex4:B, 6ex5:A, 6ex5:B, 5n57:A, 5n57:B, 6qv8:A, 6qv8:B
37 7wnk:D 202 206 0.3881 0.3861 0.3786 3.15e-39 7ddw:A, 7ddw:B, 7ddw:C, 7ddw:D, 7ddw:E, 7ddw:F, 6m30:A, 6m30:B, 6m30:C, 6m30:D, 6m30:E, 6m30:F, 7w6w:A, 7w6w:B, 7w6w:D, 7wnk:A, 7wnk:B, 7wnk:C, 7wnl:A, 7wnl:B, 7wnl:C, 7wnl:D, 5x2j:A
38 1dt0:A 197 194 0.3781 0.3858 0.3918 1.80e-38 1dt0:B, 1dt0:C, 3sdp:A, 3sdp:B
39 8avl:A 192 195 0.3781 0.3958 0.3897 1.94e-38 8avl:B, 8avl:C, 8avl:D, 8avl:E, 8avl:F, 8avl:G, 8avl:H, 8avm:A, 8avm:B, 8avm:C, 8avm:D, 8avm:E, 8avm:F
40 5n56:A 198 200 0.3682 0.3737 0.3700 4.89e-38 6ex3:A, 6ex3:B, 6ex3:C, 6ex3:D, 5n56:B, 6qv9:A, 6qv9:B, 7w6w:C
41 2gpc:A 194 193 0.3682 0.3814 0.3834 8.83e-38 2gpc:B
42 2bpi:A 197 190 0.3682 0.3756 0.3895 2.35e-37 2bpi:B
43 1qnn:A 191 196 0.3831 0.4031 0.3929 3.07e-37 1qnn:B, 1qnn:C, 1qnn:D, 1uer:A, 1uer:B, 1uer:C, 1uer:D, 1ues:A, 1ues:B, 1ues:C, 1ues:D
44 3h1s:B 192 198 0.3731 0.3906 0.3788 1.05e-36 3h1s:A
45 1my6:A 198 192 0.3980 0.4040 0.4167 1.76e-36 1my6:B
46 6jov:C 198 195 0.3980 0.4040 0.4103 2.21e-36 6jov:A, 6jov:B, 6jov:D
47 2a03:A 197 188 0.3632 0.3706 0.3883 2.78e-36 2a03:B, 2goj:A, 2goj:B
48 5a9g:A 206 198 0.3483 0.3398 0.3535 4.31e-36 5a9g:B, 6gsb:A, 6gsb:B, 6gsc:A, 6gsc:B
49 2cw3:A 200 189 0.3284 0.3300 0.3492 3.64e-35 2cw3:B
50 2bkb:A 192 191 0.3632 0.3802 0.3822 4.01e-35 2bkb:B, 2bkb:C, 2bkb:D, 1isa:A, 1isa:B, 1isb:A, 1isb:B, 1isc:A, 1isc:B, 2nyb:A, 2nyb:B, 2nyb:C, 2nyb:D, 1za5:A, 1za5:B
51 8w9z:G 218 208 0.3930 0.3624 0.3798 1.66e-34 8wa0:G, 8wa1:G
52 8r5o:I 215 205 0.3781 0.3535 0.3707 3.59e-34 8qma:G, 8r6s:I, 8ras:I, 8rdj:I
53 7sbh:A 208 191 0.3532 0.3413 0.3717 1.45e-32
54 4yet:B 200 189 0.3333 0.3350 0.3545 1.58e-31 4yet:A
55 4f2n:B 210 198 0.3433 0.3286 0.3485 1.06e-30 4f2n:A, 4f2n:C, 4f2n:D, 4f2n:E, 4f2n:F, 4f2n:G, 4f2n:H, 4f2n:I, 4f2n:J, 4f2n:K, 4f2n:L
56 4l2a:A 192 205 0.3532 0.3698 0.3463 1.75e-30 4l2a:B, 4l2b:A, 4l2b:B, 4l2c:A, 4l2c:B, 4l2c:D, 4l2c:C, 4l2d:A, 4l2d:D, 4l2d:C, 4l2d:B, 3lio:A, 3lio:B, 3lj9:B, 3lj9:A, 3ljf:A, 3ljf:C, 3ljf:B, 3ljf:D
57 2w7w:A 193 192 0.3731 0.3886 0.3906 2.37e-30 2w7w:B
58 3cei:A 213 198 0.2985 0.2817 0.3030 1.85e-29 3cei:B
59 3js4:A 207 216 0.3483 0.3382 0.3241 1.29e-28 3js4:B, 3js4:C, 3js4:D
60 7azq:A 199 201 0.3632 0.3668 0.3632 2.03e-28 7azq:E, 7azr:A, 7azr:E
61 6j55:L 203 193 0.3234 0.3202 0.3368 7.89e-28 6j55:A, 6j55:B, 6j55:C, 6j55:D, 6j55:E, 6j55:F, 6j55:G, 6j55:H, 6j55:I, 6j55:J, 6j55:K
62 4h3e:A 214 201 0.3383 0.3178 0.3383 1.35e-27 4dvh:A, 4dvh:B, 4h3e:B
63 8wa0:L 235 207 0.3532 0.3021 0.3430 1.20e-25 8w9z:L, 8wa1:L
64 8r6s:N 224 218 0.3483 0.3125 0.3211 6.43e-25 7bjk:A, 7bjk:B, 7bjk:C, 7bjk:D, 7bjk:E, 8qma:L, 8r5o:N, 8ras:N, 8rdj:N
65 1unf:X 214 209 0.3532 0.3318 0.3397 2.23e-24
66 1coj:A 211 189 0.3035 0.2891 0.3228 4.99e-23
67 6yw5:44 260 186 0.2289 0.1769 0.2473 2.92e-04 6ywe:44, 6ywx:44, 6ywy:44
68 7aor:y 253 64 0.1045 0.0830 0.3281 0.26
69 8f0p:A 1116 51 0.0498 0.0090 0.1961 0.33 8f0q:A, 8f0r:A, 8f0s:A
70 6a91:A 1323 51 0.0498 0.0076 0.1961 0.40 6a95:A, 6nt3:A, 6nt4:A
71 4g10:A 263 54 0.0746 0.0570 0.2778 2.3 4yav:A
72 7bez:A 214 34 0.0597 0.0561 0.3529 2.4 7bez:B, 7bf0:A, 7bf0:B, 3uk8:A, 3uk8:B
73 5iz4:A 247 43 0.0746 0.0607 0.3488 5.3
74 8ajm:B 395 50 0.0746 0.0380 0.3000 6.4 8t9a:B
75 7mr4:C 1083 73 0.0995 0.0185 0.2740 7.0
76 7dfw:A 957 20 0.0547 0.0115 0.5500 7.1 7n4u:A, 7n4u:B, 7n4v:A, 7n4v:B, 7n4x:A
77 7dfz:A 897 20 0.0547 0.0123 0.5500 7.4
78 7df8:A 918 20 0.0547 0.0120 0.5500 7.5
79 3k70:C 1121 73 0.0995 0.0178 0.2740 7.6 3k70:F, 5ld2:C, 7mr3:C, 6sjb:C, 6sje:C, 6sjf:C, 6sjg:C, 6t2u:C, 6t2v:C, 1w36:C
80 8b1t:C 1080 73 0.0995 0.0185 0.2740 7.7 8b1u:C, 1w36:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218