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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
APATPYQEDIARYWNNEARPVNLRLGDVDGLYHHHYGIGPVDRAALGDPEHSEYEKKVIAELHRLESAQAEFLMDHLGQA
GPDDTLVDAGCGRGGSMVMAHRRFGSRVEGVTLSAAQADFGNRRARELRIDDHVRSRVCNMLDTPFDKGAVTASWNNEST
MYVDLHDLFSEHSRFLKVGGRYVTITGCWNPRYGQPSKWVSQINAHFECNIHSRREYLRAMADNRLVPHTIVDLTPDTLP
YWELRATSSLVTGIEKAFIESYRDGSFQYVLIAADRV

The query sequence (length=277) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3vc1:D 288 277 1.0000 0.9618 1.0000 0.0 4f86:D, 4f86:G, 3vc1:A, 3vc1:B, 3vc1:C, 3vc1:E, 3vc1:F, 3vc1:G, 3vc1:H, 3vc1:I, 3vc1:J, 3vc1:K, 3vc1:L, 3vc2:A, 3vc2:B, 3vc2:C, 3vc2:D, 3vc2:E, 3vc2:F, 3vc2:G, 3vc2:H, 3vc2:I, 3vc2:J, 3vc2:K, 3vc2:L
2 4f86:A 275 275 0.8845 0.8909 0.8909 0.0 4f84:A, 4f86:B, 4f86:C, 4f86:E, 4f86:F, 4f86:H, 4f86:I, 4f86:J, 4f86:K, 4f86:L
3 7fbo:A 282 158 0.1625 0.1596 0.2848 1.71e-10 7fbh:B, 7fbh:C, 7fbo:B, 7fbo:C
4 5gm2:B 282 111 0.1083 0.1064 0.2703 4.63e-07 5gm1:A, 5gm1:B, 5gm1:C, 5gm1:D, 5gm1:E, 5gm1:F, 5gm1:G, 5gm1:H, 5gm1:I, 5gm1:J, 5gm1:K, 5gm1:L, 5gm1:M, 5gm1:N, 5gm1:O, 5gm1:P, 5gm1:Q, 5gm1:R, 5gm2:A, 5gm2:C, 5gm2:D, 5gm2:E, 5gm2:F, 5gm2:G, 5gm2:H, 5gm2:I, 5gm2:J, 5gm2:L, 5gm2:M, 5gm2:N, 5gm2:O, 5gm2:P, 5gm2:Q, 5gm2:R
5 3kkz:A 256 103 0.0975 0.1055 0.2621 1.35e-06 3kkz:B
6 7v6h:A 267 103 0.1155 0.1199 0.3107 1.39e-06 7v6h:B
7 3t7s:A 246 104 0.0830 0.0935 0.2212 5.91e-06 3t7s:B, 3t7s:C, 3t7s:D, 3t7t:A, 3t7t:B, 3t7t:C, 3t7t:D
8 6uv6:C 264 99 0.1119 0.1174 0.3131 6.54e-06 6uv6:A, 6uv6:B
9 6hp2:A 297 199 0.1552 0.1448 0.2161 1.48e-05
10 5z9o:A 373 143 0.1372 0.1019 0.2657 4.66e-05 5z9o:B
11 3bus:A 251 98 0.1047 0.1155 0.2959 5.13e-05 3bus:B
12 4ine:A 431 152 0.1336 0.0858 0.2434 9.16e-05 4ine:B
13 3sxj:A 245 107 0.0866 0.0980 0.2243 1.04e-04 3sxj:B, 3t0i:A, 3t0i:B
14 5fcd:A 228 86 0.0758 0.0921 0.2442 2.49e-04 5fcd:B
15 1tpy:A 285 95 0.1191 0.1158 0.3474 2.55e-04
16 4pne:B 272 96 0.0975 0.0993 0.2812 2.61e-04 4pne:A
17 5wp4:A 485 143 0.1191 0.0680 0.2308 0.001
18 4krh:A 430 132 0.1372 0.0884 0.2879 0.001 4krh:B, 4kri:A, 4kri:B, 4kri:C
19 1kpg:A 285 57 0.0830 0.0807 0.4035 0.001 1kpg:B, 1kpg:C, 1kpg:D, 1kph:A, 1kph:B, 1kph:C, 1kph:D
20 5gm2:K 267 111 0.1011 0.1049 0.2523 0.002
21 1wzn:A 244 230 0.2058 0.2336 0.2478 0.002 1wzn:B, 1wzn:C
22 7qos:A 352 143 0.1119 0.0881 0.2168 0.004 7qos:B
23 7lxi:A 279 77 0.0794 0.0789 0.2857 0.005 7mcj:A, 7mcj:B
24 5wp5:A 463 108 0.0939 0.0562 0.2407 0.008 5wp5:B
25 7q2d:A 286 86 0.1011 0.0979 0.3256 0.011 2fk8:A, 3ha3:A, 3ha5:A, 3ha7:A, 7q2b:A, 7q2c:A, 7q2e:A, 7q2f:A, 7q2g:A, 7q2h:A
26 1l1e:A 272 76 0.0830 0.0846 0.3026 0.012 1l1e:B
27 3hem:A 291 131 0.1227 0.1168 0.2595 0.085 1kpi:A
28 6p3o:A 341 56 0.0614 0.0499 0.3036 0.11 6p3m:A, 6p3n:A
29 9fcx:A 214 125 0.1264 0.1636 0.2800 0.12 9fcd:A, 9fcl:A, 9fcq:A, 9fcs:A, 9fcs:B, 9fcu:A, 9fcu:B, 9fcu:C, 9fcu:D, 9fcx:B, 9fcy:A, 9fcy:B, 9fcy:C, 9fcy:D, 9fd3:A, 9g0k:A, 9g0k:B
30 8eg0:A 230 123 0.1155 0.1391 0.2602 0.14 3ckk:A, 8cth:A, 8cti:A, 8d59:A, 8d5b:A, 8d9l:A, 7ogj:A, 7ogj:B, 7pl1:A
31 6bqc:A 348 69 0.0722 0.0575 0.2899 0.25
32 4x36:A 318 83 0.0903 0.0786 0.3012 0.30 2bml:B, 5ctv:A, 1h8g:A, 1h8g:B, 1hcx:A, 1hcx:B, 4ivv:A, 4iwt:A, 4iwt:B
33 5je1:A 244 165 0.1444 0.1639 0.2424 0.47 5jdy:A, 5jdy:B, 5jdz:A, 5jdz:B, 5je0:A, 5je0:B, 5je1:B, 5je2:A, 5je2:B, 5je3:A, 5je3:B, 5je4:A, 5je4:B, 5je5:A
34 2vdv:E 216 115 0.1011 0.1296 0.2435 0.51 2vdv:F
35 4iv8:A 245 145 0.0939 0.1061 0.1793 0.72 4iv8:B
36 4mwz:B 265 113 0.0794 0.0830 0.1947 0.73 4iv0:A, 4iv0:B, 4mwz:A
37 6kvm:B 179 34 0.0469 0.0726 0.3824 0.95
38 1ve3:B 226 133 0.1264 0.1549 0.2632 1.1 1ve3:A
39 5bxy:A 155 82 0.0686 0.1226 0.2317 1.6 5bxy:B
40 3uj7:A 259 113 0.0650 0.0695 0.1593 2.2 4fgz:A, 4fgz:B, 4r6w:A, 4r6w:B, 4r6x:A, 4r6x:B, 3uj6:A, 3uj7:B, 3uj8:A, 3uj9:A, 3uja:A, 3ujb:A, 3ujb:B, 3ujc:A, 3ujd:A
41 6cu5:A 314 109 0.1011 0.0892 0.2569 2.6 6cu5:B, 8ft7:A, 8ft7:B
42 5fad:A 160 54 0.0505 0.0875 0.2593 2.7 5fa8:A
43 6ecv:A 286 132 0.1119 0.1084 0.2348 2.7 6ecu:A, 6ecu:B, 6ecv:B, 6ecw:A, 6ecw:B
44 8fjm:A 251 50 0.0505 0.0558 0.2800 2.8 8fjm:B, 8fjn:A
45 3gcz:A 259 68 0.0758 0.0811 0.3088 3.3
46 6ecx:A 283 52 0.0469 0.0459 0.2500 3.5 6ect:A
47 5e8j:A 310 65 0.0650 0.0581 0.2769 4.3 3bgv:A, 3bgv:B, 3bgv:C, 3bgv:D, 5e8j:B, 5e9j:A, 5e9j:B, 5e9w:A, 5e9w:B, 5e9w:C, 5e9w:D, 3epp:A, 3epp:B, 8q69:A, 8q69:B, 8q8g:A, 8q8g:B, 8q9w:A, 8q9w:B
48 1ri1:A 252 46 0.0469 0.0516 0.2826 5.1 2hv9:A, 1ri2:A, 1ri3:A, 1ri4:A, 1z3c:A
49 6mro:A 194 118 0.1083 0.1546 0.2542 5.2 8gdu:A
50 7z0q:D 176 30 0.0397 0.0625 0.3667 5.3
51 6uk5:A 240 83 0.0866 0.1000 0.2892 5.6 6uk5:B
52 7ao7:E 402 59 0.0542 0.0373 0.2542 6.9 7ant:A, 7ant:B, 7ao7:A, 7ao7:B, 7ao7:C, 7ao7:D, 7ao7:F
53 2wa2:A 223 49 0.0578 0.0717 0.3265 7.0
54 8cmb:B 194 29 0.0397 0.0567 0.3793 8.7 8cmh:B, 4fqx:B, 2fse:B, 2fse:D, 1fv1:B, 1fv1:E, 4gbx:B, 1h15:B, 1h15:E, 8pje:E, 4x5w:B, 7yx9:B, 1zgl:B, 1zgl:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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