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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTFQD
CYSGLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMV
LTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDR
REGMSAFVEKRKANFKDH

The query sequence (length=258) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1dub:A 260 260 1.0000 0.9923 0.9923 0.0 1dub:B, 1dub:C, 1dub:E, 1dub:F, 1dub:D, 2dub:A, 2dub:B, 2dub:C, 2dub:E, 2dub:F, 2dub:D, 1ey3:A, 1ey3:B, 1ey3:C, 1ey3:D, 1ey3:E, 1ey3:F, 1mj3:A, 1mj3:B, 1mj3:C, 1mj3:E, 1mj3:F
2 2hw5:C 260 260 0.8953 0.8885 0.8885 2.22e-174
3 3h81:A 256 256 0.4961 0.5000 0.5000 5.36e-91 3h81:C, 3q0g:C, 3q0g:D, 3q0g:F, 3q0j:C, 3q0j:F
4 5zai:C 259 258 0.4729 0.4710 0.4729 2.54e-73 5zai:A, 5zai:B, 5zai:E
5 5jbx:B 261 236 0.3566 0.3525 0.3898 8.59e-43 5jbx:A
6 6slb:AAA 257 250 0.3411 0.3424 0.3520 5.49e-42 6sla:AAA, 6sla:BBB, 6sla:CCC, 6sla:DDD, 6sla:EEE, 6sla:FFF
7 3p85:A 224 186 0.2829 0.3259 0.3925 1.06e-34
8 1ef9:A 261 266 0.3062 0.3027 0.2970 1.04e-32 6n92:A, 6n92:B, 6n92:C, 6n92:D, 6n92:E, 6n92:F, 6n93:A, 6n93:B, 6n93:C, 6n93:D, 6n93:E, 6n93:F, 6n94:A, 6n94:B, 6n94:C, 6n94:D, 6n94:E, 6n94:F, 6n95:A, 6n95:B, 6n95:C, 6n95:D, 6n95:E, 6n95:F, 6n96:A, 6n96:B, 6n96:C, 6n96:D, 6n96:E, 6n96:F, 6n97:A, 6n97:B, 6n97:C, 6n97:D, 6n97:E, 6n97:F
9 4i42:A 285 262 0.3295 0.2982 0.3244 2.14e-31 4els:A, 4els:B, 4els:C, 4els:D, 4els:E, 4els:F, 4elw:A, 4elw:B, 4elw:C, 4elw:D, 4elw:E, 4elw:F, 4elx:A, 4elx:B, 4elx:C, 4elx:D, 4elx:F, 3h02:A, 3h02:B, 3h02:C, 3h02:D, 3h02:E, 3h02:F, 4i42:F, 4i42:B, 4i42:D, 4i42:C, 4i42:E, 4i42:G, 4i42:L, 4i42:H, 4i42:J, 4i42:I, 4i42:K, 3t88:A, 3t88:E, 3t88:B, 3t88:F, 3t88:C, 3t88:D
10 3pe8:A 219 192 0.2868 0.3379 0.3854 6.89e-31
11 2vss:B 247 217 0.2558 0.2672 0.3041 8.26e-30 6l3p:A, 6l3p:B, 2vss:D, 2vss:E, 2vss:F, 2vsu:A, 2vsu:B, 2vsu:D, 2vsu:E, 2vsu:F
12 3rrv:B 254 246 0.2946 0.2992 0.3089 1.64e-29 3rrv:A, 3rrv:C, 3rrv:D, 3rrv:E, 3rrv:F
13 2uzf:A 260 241 0.3140 0.3115 0.3361 4.61e-29
14 4i4z:A 275 261 0.3256 0.3055 0.3218 1.98e-28 4eml:A, 4eml:B, 4eml:C, 4eml:D, 4eml:E, 4eml:F, 4i4z:F, 4i4z:B, 4i4z:D, 4i4z:C, 4i4z:E, 4i4z:G, 4i4z:H, 4i4z:I, 4i52:A, 4i52:B, 4i52:C, 4i52:D, 4i52:E, 4i52:F, 4i52:G, 4i52:H, 4i52:I
15 1jxz:B 269 247 0.2752 0.2639 0.2874 6.01e-28 1jxz:A, 1jxz:C, 1nzy:A, 1nzy:B, 1nzy:C
16 6p5u:E 246 216 0.2481 0.2602 0.2963 1.16e-27 6p5u:A, 6p5u:B, 6p5u:C, 6p5u:D, 6p5u:F
17 7xwt:B 277 249 0.2713 0.2527 0.2811 2.35e-27 7xwv:A, 7xwv:B
18 6iun:B 692 194 0.2907 0.1084 0.3866 1.03e-24 6iun:A
19 3t3w:F 248 212 0.2674 0.2782 0.3255 2.46e-24 3t3w:A, 3t3w:B, 3t3w:C, 3t3w:D, 3t3w:E
20 3ome:C 247 213 0.2636 0.2753 0.3192 4.69e-24 3ome:A, 3ome:B, 3ome:D, 3ome:E, 3ome:F
21 6tnm:A 719 177 0.2364 0.0848 0.3446 1.08e-23
22 3zwa:A 727 187 0.2907 0.1032 0.4011 2.62e-23 5mgb:A, 5mgb:B, 5omo:A, 5omo:B, 2x58:A, 2x58:B, 6z5f:AAA, 6z5f:BBB, 6z5o:AAA, 6z5v:AAA, 6z5v:BBB, 6zib:AAA, 6zib:BBB, 6zic:AAA, 6zic:BBB, 3zw9:A, 3zw9:B, 3zwa:B, 3zwb:A, 3zwb:B, 3zwc:A, 3zwc:B
23 6ysw:A 707 196 0.2519 0.0919 0.3316 4.34e-23
24 5duf:A 245 248 0.3062 0.3224 0.3185 4.56e-23 5dtw:A, 5dtw:D, 5du4:A, 5du6:A, 5du6:B, 5du6:C, 5du8:A, 5du8:B, 5du8:C, 5duc:A, 5duc:B, 5duc:C
25 1rjn:B 275 265 0.2946 0.2764 0.2868 9.47e-22 1q51:A, 1q51:C, 1q51:D, 1q51:E, 1q51:F, 1q51:G, 1q51:H, 1q51:I, 1q51:J, 1q51:K, 1q51:L, 1rjm:A, 1rjm:B, 1rjm:C, 1rjn:A, 1rjn:C, 3t8a:B, 3t8a:C
26 3bpt:A 362 183 0.2364 0.1685 0.3333 1.01e-21
27 7bor:A 247 234 0.2558 0.2672 0.2821 2.48e-21 7bor:C
28 4qii:B 301 278 0.2984 0.2558 0.2770 1.59e-20 1q51:B, 4qii:A, 4qii:F, 4qii:E, 4qii:C, 4qii:D, 4qii:G, 4qii:L, 4qii:H, 4qii:K, 4qii:I, 4qii:J, 4qij:A, 4qij:F, 4qij:B, 4qij:E, 4qij:C, 4qij:D, 4qij:G, 4qij:K, 4qij:H, 4qij:J, 4qij:I, 4qij:L
29 6eqo:A 1804 180 0.2519 0.0360 0.3611 6.74e-20 6eqo:B
30 1wdl:A 715 179 0.2054 0.0741 0.2961 1.51e-19 2d3t:A, 2d3t:B, 1wdk:A, 1wdk:B, 1wdl:B, 1wdm:A, 1wdm:B
31 4hdt:A 340 180 0.2287 0.1735 0.3278 3.04e-19
32 4izc:B 266 194 0.2403 0.2331 0.3196 1.39e-18 4izc:A, 4izd:A, 4izd:B
33 4jvt:A 257 186 0.2171 0.2179 0.3011 1.17e-15 4omr:A
34 2a81:A 235 228 0.2364 0.2596 0.2675 3.08e-14
35 5kag:D 423 197 0.2132 0.1300 0.2792 6.87e-14 5kag:A, 5kag:B, 5kag:C, 5kag:E, 5kag:F, 5kag:G, 5kag:H, 5kag:I, 5kag:J, 5kag:K, 5kag:L, 5kah:A, 5kah:B, 5kah:C, 5kah:D, 5kah:E, 5kah:F, 5kah:G, 5kah:H, 5kah:I, 5kah:J, 5kah:K, 5kah:L, 5kaj:A, 5kaj:B, 5kaj:C, 5kaj:D, 5kaj:E, 5kaj:F, 5kaj:G, 5kaj:H, 5kaj:I, 5kaj:J, 5kaj:K, 5kaj:L, 2np9:A, 2np9:B, 2np9:C, 2pg8:A, 2pg8:B, 2pg8:C, 4ylh:A, 4ylh:B, 4ylh:C, 4ylh:D, 4ylh:E, 4ylh:F, 4ylh:G, 4ylh:H, 4ylh:I, 4ylh:J, 4ylh:K, 4ylh:L
36 1xx4:A 254 257 0.2287 0.2323 0.2296 5.25e-12
37 8oqs:B 735 178 0.2287 0.0803 0.3315 9.94e-12 4b3i:A, 4b3i:B, 4b3j:A, 4b3j:B, 7o4s:A, 7o4s:B, 7o4t:A, 7o4t:B, 7o4u:A, 7o4u:B, 7o4v:B, 7o4v:A, 8opu:A, 8opu:B, 8opv:A, 8opv:B, 8oql:A, 8oql:B, 8oqn:A, 8oqn:B, 8oqo:A, 8oqo:B, 8oqp:A, 8oqp:B, 8oqq:A, 8oqq:B, 8oqr:A, 8oqr:B, 8oqs:A, 8oqt:B, 8oqt:A, 8oqu:A, 8oqu:B, 8oqv:A, 8oqv:B, 8pf8:A, 8pf8:B
38 2j5s:A 250 193 0.1860 0.1920 0.2487 5.16e-11 2j5s:B
39 1szo:D 251 149 0.1667 0.1713 0.2886 2.60e-10 1szo:A, 1szo:B, 1szo:C, 1szo:E, 1szo:F, 1szo:G, 1szo:H, 1szo:I, 1szo:J, 1szo:K, 1szo:L
40 1sg4:B 258 257 0.2248 0.2248 0.2257 7.74e-10
41 6z1p:BI 1413 206 0.1822 0.0333 0.2282 1.05e-07
42 1k39:B 271 190 0.1860 0.1771 0.2526 9.13e-07 1hnu:A, 1k39:A, 1k39:C, 4zdb:A, 4zdb:B, 4zdb:C, 4zdc:A, 4zdc:B, 4zdc:C
43 4fnb:A 232 202 0.2171 0.2414 0.2772 2.42e-06 4fn8:A, 4fnd:A
44 6j0p:A 564 261 0.2636 0.1206 0.2605 7.00e-06 6j0p:B, 6j1e:A, 6j1f:A, 6j1f:B, 6j1g:A, 6j1i:A, 6j1j:A
45 6hiv:Cv 1059 148 0.1318 0.0321 0.2297 0.36 6hiw:Cv, 6hiy:Cv, 7pub:Cv
46 7aor:z 1071 84 0.0930 0.0224 0.2857 1.1
47 6h7f:A 671 32 0.0465 0.0179 0.3750 6.9 6h7f:B, 6h7f:C, 6h7v:B, 6hcp:A, 6hcp:B, 6hcp:C
48 7uml:C 172 16 0.0310 0.0465 0.5000 7.6 7uml:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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