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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ALKPLKTWSHLAGNRRRPSEYEVVSTNLHYFTDNPERPWELDSNLPMQTWYKKYCFDSPLKHDDWNAFRDPDQLVYRTYN
LLQDGQESYVQGLFDQLNDRGHDQMLTREWVETLARFYTPARYLFHALQMGSVYIHQIAPASTITNCATYETADHLRWLT
HTAYRTRELANCYPDVGFGKRERDVWENDPAWQGFRELIEKALIAWDWGEAFTAINLVTKPAVEEALLQQLGSLAQSEGD
TLLGLLAQAQKRDAERHRRWSSALVKMALEKEGNREVLQKWVAKWEPLADKAIEAYCSALPDGENAIVEAKSASRYVRQM
MGL

The query sequence (length=323) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1t0s:B 323 323 1.0000 1.0000 1.0000 0.0
2 3rmk:E 306 298 0.5666 0.5980 0.6141 1.58e-139 3dhg:B, 3dhg:E, 3dhh:B, 3q2a:B, 3q3m:B, 3q3m:F, 3q3o:B, 3rmk:B, 5tds:B
3 3u52:D 328 320 0.2508 0.2470 0.2531 3.69e-19 3u52:C
4 2inn:A 496 231 0.1703 0.1109 0.2381 2.54e-05 2inn:B, 2inp:A, 2inp:B, 3u52:A, 3u52:B
5 7m8q:A 515 200 0.1146 0.0718 0.1850 0.22 6d7k:A, 6d7k:E, 7m8q:E, 7m8r:A, 7m8r:E, 1mhy:D, 1mhz:D, 7s6q:A, 7s6q:E, 7s6r:A, 7s6r:E, 7s6s:A, 7s6s:E, 7s6t:A, 7s6t:E, 7s7h:A, 7s7h:E, 6vk4:A, 6vk4:E, 6vk5:A, 6vk5:E, 6vk6:A, 6vk7:A, 6vk8:A, 6vk8:E, 6yd0:D, 6ydi:D, 6ydu:D, 6yy3:D
6 3zx7:A 296 41 0.0464 0.0507 0.3659 2.6 3zxd:C, 3zxg:A
7 8q1b:E 182 75 0.0619 0.1099 0.2667 2.9 8q1b:P
8 7rja:C 181 59 0.0464 0.0829 0.2542 4.6 7rja:M, 7rjb:E, 7rjc:E, 7rjd:E, 7rje:C, 7rje:M
9 9exw:A 148 41 0.0372 0.0811 0.2927 5.2 9exw:B, 9exx:A, 9exx:B, 9exy:A, 7lmt:A, 7lmt:H, 7lmt:B, 7lmt:C, 7lmt:D, 7lmt:E, 7lmt:F, 7lmt:G, 7mdn:A, 7mdn:H, 7mdn:B, 7mdn:C, 7mdn:D, 7mdn:E, 7mdn:F, 7mdn:G, 6ue6:A, 6ue6:B, 6ue6:D, 6ue6:E, 6ue6:G, 6ue6:H, 5vc8:A, 7vln:B, 6xcg:A, 6xcg:B, 6xcg:C
10 6agz:A 386 49 0.0495 0.0415 0.3265 5.3 6agz:B
11 1fzi:A 512 119 0.0774 0.0488 0.2101 6.1 1fyz:A, 1fyz:B, 1fz0:A, 1fz0:B, 1fz1:A, 1fz1:B, 1fz2:A, 1fz2:B, 1fz3:A, 1fz3:B, 1fz4:A, 1fz4:B, 1fz5:A, 1fz5:B, 1fz6:A, 1fz6:B, 1fz7:A, 1fz7:B, 1fz8:A, 1fz8:B, 1fz9:A, 1fz9:B, 1fzh:A, 1fzh:B, 1fzi:B, 4gam:A, 4gam:F, 4gam:K, 4gam:P, 1mmo:D, 1mmo:E, 1mty:D, 1mty:E, 7tc7:D, 7tc7:E, 7tc8:D, 7tc8:E, 1xmf:A, 1xmf:B, 1xmh:A, 1xmh:B, 1xu3:A, 1xu3:B, 1xu5:A, 1xu5:B, 1xvb:A, 1xvb:B, 1xvc:A, 1xvc:B, 1xvd:A, 1xvd:B, 1xve:A, 1xve:B, 1xvf:A, 1xvf:B, 1xvg:A, 1xvg:B
12 8rwl:A 312 93 0.0898 0.0929 0.3118 6.8 9end:A, 9end:B, 8rs5:A, 8rs5:B, 8rwl:B
13 3dje:B 437 51 0.0526 0.0389 0.3333 7.2 3djd:A, 3djd:B, 3dje:A
14 2mxf:A 47 30 0.0372 0.2553 0.4000 8.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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