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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AKLWDSKMFAEIMMKIEEYISKQAKASEVAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYI
RTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSEEELERLEEACDMALELNASKHRIYEYVESRMSFIA
PNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVA
AKCTLAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLRKKRGGRRYRKMKERLGLTEIRKQANRMS
FGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARISKTLQRTLQKQS

The query sequence (length=373) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5o9z:H 413 381 1.0000 0.9031 0.9790 0.0 6ahd:L, 8h6e:4D, 8h6k:4D, 8h6l:4D, 2ozb:B, 2ozb:E, 8q7n:L, 8qo9:L, 8qoz:L, 8qp8:L, 8qp9:L, 8qpa:L, 8qpb:L, 8qpe:L, 8qpk:L, 6qw6:4C, 6qx9:4C, 8qxd:L, 8qzs:L, 8r08:L, 8r09:L, 8r0b:L, 8rm5:L, 3siu:B, 3siu:E, 3siv:B, 3siv:E, 3siv:H, 3siv:K, 8y6o:L
2 8r0a:L 292 327 0.7748 0.9897 0.8838 0.0 6ah0:L
3 3jcm:I 416 362 0.2976 0.2668 0.3066 2.31e-47 5gan:F, 5gap:F, 5nrl:F, 5zwm:L, 5zwo:L
4 7mq8:SB 440 237 0.1877 0.1591 0.2954 5.46e-33 7mq9:SB, 7mqa:SB
5 6rxt:CD 420 222 0.1877 0.1667 0.3153 6.02e-31 5oql:U, 6rxu:CD, 6rxv:CD, 6rxx:CD, 6rxy:CD, 6rxz:CD
6 4by9:F 366 236 0.1823 0.1858 0.2881 3.00e-26 4by9:I, 4by9:C, 4by9:L, 3nmu:A, 3nmu:B, 3nvi:A, 3nvi:C, 3nvk:A, 3nvk:F
7 6nd4:b 425 261 0.1796 0.1576 0.2567 1.21e-25 5wlc:SB
8 7aju:CE 436 244 0.1716 0.1468 0.2623 2.79e-25 7ajt:CE, 7d4i:3E, 7d5s:3E, 7d5t:3E, 7d63:3E, 6ke6:3E, 6lqp:3E, 6lqq:3E, 6lqr:3E, 6lqs:3E, 6lqt:3E, 6lqu:3E, 6lqv:3E, 7suk:SB, 5wyj:3E, 5wyk:3E, 6zqa:CE, 6zqb:CE, 6zqc:CE, 6zqd:CE, 6zqe:CE
9 7mq8:SA 396 243 0.1582 0.1490 0.2428 1.60e-22 7mq9:SA, 7mqa:SA
10 5gin:A 375 241 0.1823 0.1813 0.2822 1.17e-20 5gin:B, 5gin:K, 5gio:A, 5gio:B, 5gio:K, 5gip:A, 5gip:B, 5gip:K, 5gip:L, 3id5:A, 3id5:E, 5jpq:S, 5jpq:T, 3pla:A, 3pla:B, 3pla:K, 7xpl:A, 7xpl:B
11 5oql:T 387 225 0.1582 0.1525 0.2622 4.83e-19 6rxt:CC, 6rxu:CC, 6rxv:CC, 6rxy:CC, 6rxz:CC
12 7ajt:CD 380 245 0.1662 0.1632 0.2531 2.24e-16 7aju:CD, 7d4i:3D, 7d5s:3D, 7d5t:3D, 7d63:3D, 6ke6:3D, 6lqp:3D, 6lqq:3D, 6lqr:3D, 6lqs:3D, 6lqt:3D, 6lqu:3D, 6lqv:3D, 6nd4:a, 7suk:SA, 5wlc:SA, 5wyj:3D, 5wyk:3D, 6zqa:CD, 6zqb:CD, 6zqc:CD, 6zqd:CD
13 8z9e:H 553 146 0.0777 0.0524 0.1986 2.7
14 2e74:C 288 24 0.0295 0.0382 0.4583 5.1 2d2c:C, 2d2c:P, 2e75:C, 2e76:C, 4h0l:C, 4h13:C, 4i7z:C, 4pv1:C, 1vf5:C, 1vf5:P
15 7mq8:SL 192 43 0.0295 0.0573 0.2558 6.9 7mq9:SL, 7mqa:SL
16 5jr6:B 545 72 0.0483 0.0330 0.2500 7.7
17 5hxx:A 424 57 0.0429 0.0377 0.2807 7.8 5hxx:B, 5iwq:A, 5iwq:B, 3ppl:A, 3ppl:B
18 3oib:A 381 41 0.0429 0.0420 0.3902 9.3 3oib:B, 3p4t:A, 3p4t:B
19 2uzh:C 155 59 0.0563 0.1355 0.3559 9.4 2uzh:A, 2uzh:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218