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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AIADVGTDRYAPYFAYAAAQPSDEVTTVRGLSNPLIKTAPVTLPFDLGQAVADNCLSLSGMGYYLGLGGCCPTCAAAEPR
LGRSDRAALVLAYVQQLNSIYEYRVFLASVAARDPSERALEEVLAHPELFFAYYVLRDGRDVRVLFFEDPDAQGALMMYV
VFPEKSVHVHHRVLDRLLGACAGHRIVAHVWQTMFVLVVRKKGDDVPAVSASDIYCKMRDISFDGELLLEYKRLYAAFED
FRPPR

The query sequence (length=245) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4z3u:B 252 245 0.9673 0.9405 0.9673 1.24e-169 5e8c:A, 5fki:1A, 5fki:1C, 5fki:1E, 5fki:1G, 5fki:1I, 5fki:1K, 5fki:1M, 5fki:1O, 5fki:1Q, 5fki:1S, 5fki:1U, 5fki:1W, 5fki:1Y, 5fki:10, 5fki:12, 5fki:14, 5fki:16, 5fki:18, 5fki:2A, 5fki:2C, 5fki:2E, 5fki:2G, 5fki:2I, 5fki:2K, 5fki:2M, 5fki:2O, 5fki:2Q, 5fki:2S, 5fki:2U, 5fki:2W, 5fki:2Y, 5fki:20, 5fki:22, 5fki:24, 5fki:26, 5fki:28, 5fki:3A, 5fki:3C, 5fki:3E, 5fki:3G, 5fki:3I, 5fki:3K, 4z3u:D
2 7pab:A 415 241 0.6204 0.3663 0.6307 5.85e-102 7pab:C
3 8g6d:B 253 249 0.5551 0.5375 0.5462 3.95e-94 8g6d:D, 8g6d:F, 8g6d:H, 8g6d:J, 8g6d:L, 4zxs:B, 4zxs:D
4 7t7i:D 242 150 0.1510 0.1529 0.2467 2.32e-07 7t7i:B, 7t7i:H, 7t7i:J
5 7t7i:F 208 150 0.1469 0.1731 0.2400 1.40e-05
6 5dob:A 237 161 0.1551 0.1603 0.2360 7.68e-04 5d5n:B, 5doc:A, 5doc:B, 5doe:B
7 5wwr:A 461 88 0.0980 0.0521 0.2727 1.1 5wwr:B, 5wws:A, 5wws:B, 5wwt:A, 5wwt:B
8 3gnr:A 478 54 0.0694 0.0356 0.3148 2.0 3wba:A, 3wbe:A
9 4yuu:V1 129 18 0.0408 0.0775 0.5556 4.4 4yuu:v1, 4yuu:V2, 4yuu:v2
10 6fxc:Ab 226 74 0.0776 0.0841 0.2568 6.1 7bge:b, 8bh6:b, 8bh7:b, 8byv:b, 6fxc:Bb, 7kwg:b, 5li0:b, 5nd8:b, 5nd9:b, 5ngm:Ab, 7nhl:c, 7nhm:c, 8p2f:c, 8p2g:c, 8p2h:c, 7p48:b, 6s0x:b, 6s13:b, 8y38:b, 8y39:b, 6yef:b
11 5j60:A 316 74 0.0816 0.0633 0.2703 8.8 5j60:D, 5j60:B, 5j60:C, 6xtf:A, 6xtf:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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