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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AGGLSQLVAYGAQDVYLTGNPQITFFKTVYRRYTNFAIESIQQTINGSVGFGNKVSTQISRNGDLITDIVVEFVLTKGGN
GGTTYYPAEELLQDVELEIGGQRIDKHYNDWFRTYDALFRMNDDRYNYRRMTDWVNNELVGAQKRFYVPLIFFFNQTPGL
ALPLIALQYHEVKLYFTLASQVQGVNYNGSSAIAGAAQPTMSVWVDYIFLDTQERTRFAQLPHEYLIEQLQFTGSETATP
SATTQASQNIRLNFNHPTKYLAWNFNNPTNYGQYTALANIPGACSGAGTAAATVTTPDYGNTGTYNEQLAVLDSAKIQLN
GQDRFATRKGSYFNKVQPYQSIGGVTPAGVYLYSFALKPAGRQPSGTCNFSRIDNATLSLTYKTCSIDATSPAAVLGNTE
TVTANTATLLTALNIYAKNYNVLRIMSGMGGLAYAN

The query sequence (length=436) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5tip:A 436 436 1.0000 1.0000 1.0000 0.0 5tip:B, 5tip:C, 5tip:D, 5tiq:A, 5tiq:B
2 8h2i:de 397 439 0.3555 0.3904 0.3531 1.81e-79
3 8h2i:cX 401 441 0.3784 0.4115 0.3741 2.12e-79 8h2i:cZ, 8h2i:dd, 8h2i:dk, 8h2i:dl
4 4a44:A 140 130 0.0780 0.2429 0.2615 0.51 4a41:A, 4a45:A, 4aax:A
5 8dla:A 203 68 0.0436 0.0936 0.2794 0.73 8dla:C, 8dla:B, 8dla:D, 8dla:G, 8dla:I, 8dla:M
6 4tqm:A 402 34 0.0321 0.0348 0.4118 0.83
7 2a1t:C 388 35 0.0298 0.0335 0.3714 1.3 2a1t:A, 2a1t:B, 2a1t:D, 1egc:A, 1egc:B, 1egc:C, 1egc:D, 1egd:A, 1egd:B, 1egd:C, 1egd:D, 1ege:A, 1ege:B, 1ege:C, 1ege:D, 4p13:A, 4p13:B, 4p13:C, 4p13:D, 8sgp:A, 8sgp:B, 8sgp:C, 8sgp:D, 1t9g:A, 1t9g:B, 1t9g:C, 1t9g:D
8 4kto:A 377 35 0.0390 0.0451 0.4857 3.5 4kto:C, 4kto:B, 4kto:D
9 4bxs:V 1262 32 0.0321 0.0111 0.4375 5.8
10 7kz3:D 439 99 0.0550 0.0547 0.2424 6.2 7kz5:A, 7kz5:B, 7kz5:C, 7kz5:D, 7kz6:A, 7kz6:B, 7kz6:C, 7kz6:D, 7kzd:A, 7kzd:B, 7kzd:C, 7kzd:D, 7kzd:E, 7kzd:H, 7kzd:F, 7kzd:G
11 5mlz:A 355 23 0.0275 0.0338 0.5217 6.7 5mm0:A, 5mm1:A
12 3mdd:A 385 34 0.0275 0.0312 0.3529 7.3 3mdd:B, 3mde:A, 3mde:B, 1udy:A, 1udy:B, 1udy:C, 1udy:D
13 7ux7:A 378 39 0.0321 0.0370 0.3590 9.1 7ux6:A, 7ux6:B, 7ux7:B, 7ux8:A, 7ux8:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218