Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 58 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1dg5:A (2.0) BS02 TOP 1.5.1.3 GO:0004146 ... P9WNX1 10623528 MOAD: Ki=88uM
    BindingDB: IC50=88000nM
    2 1dyr:A (1.86) BS02 TOP 1.5.1.3 GO:0004146 ... P16184 7866743 MOAD: ic50=20uM
    BindingDB: IC50=12000nM, Ki=280000nM
    3 2bfm:A (2.6) BS02 TOP 1.5.1.33 GO:0004155 ... Q01782 16055151
    4 2bfm:B (2.6) BS02 TOP 1.5.1.33 GO:0004155 ... Q01782 16055151
    5 2w3a:A (1.5) BS02 TOP 1.5.1.3 GO:0000900 ... P00374 N/A BindingDB: IC50=680000nM, Ki=19070nM
    6 2w3a:B (1.5) BS02 TOP 1.5.1.3 GO:0000900 ... P00374 N/A BindingDB: IC50=680000nM, Ki=19070nM
    7 2w3v:A (1.89) BS02 TOP 1.5.1.3 GO:0000166 ... O30463 N/A BindingDB: IC50=190nM
    8 2w9g:A (1.95) BS01 TOP 1.5.1.3 GO:0004146 ... P0A017 19280600 MOAD: Kd=0.97nM
    BindingDB: Ki=3.4nM, IC50=14.4nM
    9 2w9h:A (1.48) BS01 TOP 1.5.1.3 GO:0004146 ... P0A017 19280600 MOAD: Kd=430nM
    PDBbind: -logKd/Ki=6.37, Kd=430nM
    BindingDB: Ki=3.4nM, IC50=14.4nM
    10 2w9s:A (1.8) BS02 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    11 2w9s:B (1.8) BS02 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    12 2w9s:C (1.8) BS02 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    13 2w9s:D (1.8) BS01 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    14 2w9s:E (1.8) BS01 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    15 2w9s:F (1.8) BS01 TOP 1.5.1.3 GO:0004146 ... P13955 19280600 MOAD: Kd=730nM
    BindingDB: IC50=1.51e+4nM
    16 3fl9:A (2.4) BS02 TOP 1.5.1.3 GO:0000166 ... Q81R22 19364848 MOAD: ic50=77.2mM
    PDBbind: -logKd/Ki=1.11, IC50=77.2mM
    BindingDB: Ki=24100nM, IC50=71000nM
    17 3fl9:B (2.4) BS02 TOP 1.5.1.3 GO:0000166 ... Q81R22 19364848 MOAD: ic50=77.2mM
    BindingDB: Ki=24100nM, IC50=71000nM
    18 3fl9:C (2.4) BS02 TOP 1.5.1.3 GO:0000166 ... Q81R22 19364848 MOAD: ic50=77.2mM
    BindingDB: Ki=24100nM, IC50=71000nM
    19 3fl9:D (2.4) BS02 TOP 1.5.1.3 GO:0000166 ... Q81R22 19364848 MOAD: ic50=77.2mM
    BindingDB: Ki=24100nM, IC50=71000nM
    20 3fl9:E (2.4) BS01 TOP 1.5.1.3 GO:0000166 ... Q81R22 19364848 MOAD: ic50=77.2mM
    BindingDB: Ki=24100nM, IC50=71000nM
    21 3fl9:F (2.4) BS02 TOP 1.5.1.3 GO:0000166 ... Q81R22 19364848 MOAD: ic50=77.2mM
    BindingDB: Ki=24100nM, IC50=71000nM
    22 3fl9:G (2.4) BS01 TOP 1.5.1.3 GO:0000166 ... Q81R22 19364848 MOAD: ic50=77.2mM
    BindingDB: Ki=24100nM, IC50=71000nM
    23 3fl9:H (2.4) BS02 TOP 1.5.1.3 GO:0000166 ... Q81R22 19364848 MOAD: ic50=77.2mM
    BindingDB: Ki=24100nM, IC50=71000nM
    24 3frb:X (2.0) BS02 TOP 1.5.1.3 GO:0004146 ... P0A017 19211577 MOAD: Ka=5800000M^-1
    BindingDB: Ki=3.4nM, IC50=14.4nM
    25 3fre:X (2.2) BS02 TOP 1.5.1.3 GO:0004146 ... P0A017 19211577 MOAD: Ki=0.0006uM
    BindingDB: Ki=3.4nM, IC50=14.4nM
    26 3jw3:A (2.57) BS02 TOP 1.5.1.3 GO:0000166 ... Q81R22 N/A BindingDB: Ki=24100nM, IC50=71000nM
    27 3jw3:B (2.57) BS02 TOP 1.5.1.3 GO:0000166 ... Q81R22 N/A BindingDB: Ki=24100nM, IC50=71000nM
    28 3jw5:A (2.89) BS02 TOP 1.5.1.3 GO:0000166 ... Q81R22 N/A BindingDB: Ki=24100nM, IC50=71000nM
    29 3jw5:B (2.89) BS02 TOP 1.5.1.3 GO:0000166 ... Q81R22 N/A BindingDB: Ki=24100nM, IC50=71000nM
    30 3n0h:A (1.92) BS01 TOP 1.5.1.3 GO:0000900 ... P00374 21684339 MOAD: Ki=617nM
    PDBbind: -logKd/Ki=6.21, Ki=617nM
    BindingDB: IC50=680000nM, Ki=19070nM
    31 3n0h:A (1.92) BS02 TOP 1.5.1.3 GO:0000900 ... P00374 21684339 MOAD: Ki=617nM
    PDBbind: -logKd/Ki=6.21, Ki=617nM
    BindingDB: IC50=680000nM, Ki=19070nM
    32 3s3v:A (1.53) BS01 TOP 1.5.1.3 GO:0000900 ... P00374 21684339 MOAD: Ki=593nM
    PDBbind: -logKd/Ki=6.23, Ki=593nM
    BindingDB: IC50=680000nM, Ki=19070nM
    33 3s3v:A (1.53) BS02 TOP 1.5.1.3 GO:0000900 ... P00374 21684339 MOAD: Ki=593nM
    PDBbind: -logKd/Ki=6.23, Ki=593nM
    BindingDB: IC50=680000nM, Ki=19070nM
    34 3tq8:A (1.9) BS02 TOP 1.5.1.3 GO:0000166 ... Q83AB2 26033498
    35 4g8z:X (1.75) BS01 TOP 1.5.1.3 GO:0004146 ... P16184 23545530 MOAD: Ki=227nM
    BindingDB: IC50=12000nM, Ki=280000nM
    36 4km2:A (1.4) BS02 TOP 1.5.1.3 GO:0004146 ... P9WNX1 24210757 MOAD: Kd=1.43uM
    PDBbind: -logKd/Ki=5.84, Kd=1.43uM
    BindingDB: IC50=88000nM
    37 4km2:B (1.4) BS02 TOP 1.5.1.3 GO:0004146 ... P9WNX1 24210757 MOAD: Kd=1.43uM
    BindingDB: IC50=88000nM
    38 4xt7:A (2.3) BS02 TOP ? GO:0000166 ... P71968 26848874 MOAD: ic50=93.5uM
    39 6rul:A (2.2) BS01 TOP 1.5.1.3 GO:0004146 ... P0ABQ4 32066961 BindingDB: IC50=10nM, Ki=3.0nM
    40 6rum:A (1.6) BS01 TOP 1.5.1.3 GO:0004146 ... P0ABQ4 32066961 BindingDB: IC50=10nM, Ki=3.0nM
    41 6xg4:A (2.1) BS02 TOP 1.5.1.3 GO:0004146 ... P0ABQ4 34011959 BindingDB: IC50=10nM, Ki=3.0nM
    42 6xg5:A (1.9) BS02 TOP 1.5.1.3 GO:0004146 ... P0ABQ4 34011959 BindingDB: IC50=10nM, Ki=3.0nM
    43 7f3z:A (2.6) BS03 TOP 1.5.1.3
    2.1.1.45    		 GO:0004146 ... P13922 34614393 BindingDB: Ki=10.3nM, IC50=10nM
    44 7f3z:B (2.6) BS04 TOP 1.5.1.3
    2.1.1.45    		 GO:0004146 ... P13922 34614393 BindingDB: Ki=10.3nM, IC50=10nM
    45 7myl:A (2.15) BS01 TOP 1.5.1.3 GO:0000166 ... A4GRC7 35562546
    46 7myl:B (2.15) BS01 TOP 1.5.1.3 GO:0000166 ... A4GRC7 35562546
    47 7myl:C (2.15) BS01 TOP 1.5.1.3 GO:0000166 ... A4GRC7 35562546
    48 7myl:D (2.15) BS01 TOP 1.5.1.3 GO:0000166 ... A4GRC7 35562546
    49 7myl:E (2.15) BS01 TOP 1.5.1.3 GO:0000166 ... A4GRC7 35562546
    50 7myl:F (2.15) BS01 TOP 1.5.1.3 GO:0000166 ... A4GRC7 35562546
    51 7mym:A (3.04) BS03 TOP 1.5.1.3 GO:0004146 ... P0ABQ4 35562546
    52 7mym:B (3.04) BS02 TOP 1.5.1.3 GO:0004146 ... P0ABQ4 35562546
    53 7mym:C (3.04) BS03 TOP 1.5.1.3 GO:0004146 ... P0ABQ4 35562546
    54 7nae:A (2.35) BS01 TOP 1.5.1.3 GO:0004146 ... P0ABQ4 35562546
    55 7r6g:A (2.61) BS01 TOP 1.5.1.3 GO:0004146 ... P11731 35562546
    56 7r6g:B (2.61) BS01 TOP 1.5.1.3 GO:0004146 ... P11731 35562546
    57 8sze:A (2.5) BS01 TOP 1.5.1.3 GO:0004146 ... A0A3N4BLI0 N/A
    58 8sze:B (2.5) BS01 TOP 1.5.1.3 GO:0004146 ... A0A3N4BLI0 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218