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BioLiP
Download all results in tab-seperated text for 31 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1m6e:X (3.0) BS02 SAL 2.1.1.274 GO:0008168 ... Q9SPV4 12897246
    2 1pth:A (3.4) BS02 SAL 1.14.99.1 GO:0001516 ... P05979 7552725
    3 1pth:B (3.4) BS02 SAL 1.14.99.1 GO:0001516 ... P05979 7552725
    4 1y7i:A (2.1) BS01 SAL 3.1.1.- GO:0009694 ... Q6RYA0 15668381 MOAD: Kd=90nM
    5 1y7i:A (2.1) BS02 SAL 3.1.1.- GO:0009694 ... Q6RYA0 15668381 MOAD: Kd=90nM
    6 1y7i:B (2.1) BS01 SAL 3.1.1.- GO:0009694 ... Q6RYA0 15668381 MOAD: Kd=90nM
    7 2i30:A (2.9) BS01 SAL ? GO:0003677 ... P02768 17067818 BindingDB: Ki=5888436553556nM
    8 3b9m:A (2.7) BS02 SAL ? GO:0003677 ... P02768 18258455 BindingDB: Ki=5888436553556nM
    9 3w1w:A (2.006) BS02 SAL 4.98.1.1 GO:0004325 ... P22830 24043703
    10 5u6m:A (2.568) BS03 SAL 2.4.1.- GO:0005829 ... O22822 28425481
    11 5u6m:B (2.568) BS03 SAL 2.4.1.- GO:0005829 ... O22822 28425481
    12 5u6n:A (2.001) BS06 SAL 2.4.1.- GO:0005829 ... O22822 28425481
    13 5u6n:B (2.001) BS05 SAL 2.4.1.- GO:0005829 ... O22822 28425481
    14 5x80:A (2.4) BS01 SAL ? GO:0003677 ... P9WME9 28743871 MOAD: Ka=24500M^-1
    15 5x80:B (2.4) BS01 SAL ? GO:0003677 ... P9WME9 28743871 MOAD: Ka=24500M^-1
    16 5x80:B (2.4) BS02 SAL ? GO:0003677 ... P9WME9 28743871 MOAD: Ka=24500M^-1
    17 5yjs:A (2.16) BS01 SAL ? GO:0046872 ... A0A452CSM5 30181145
    18 5yjs:B (2.16) BS01 SAL ? GO:0046872 ... A0A452CSM5 30181145
    19 6jqx:A (1.672) BS01 SAL 4.1.1.91 GO:0005737 ... P0CT50 34553918
    20 6jqx:B (1.672) BS01 SAL 4.1.1.91 GO:0005737 ... P0CT50 34553918
    21 6l4m:A (3.302) BS01 SAL ? N/A B0JEU3 31753489
    22 6ux1:A (1.36) BS02 SAL 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 32244293 MOAD: ic50=6.6mM
    BindingDB: Ki=7100nM, IC50=680000nM
    23 6ux1:A (1.36) BS03 SAL 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 32244293 MOAD: ic50=6.6mM
    BindingDB: Ki=7100nM, IC50=680000nM
    24 6ux1:A (1.36) BS04 SAL 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 32244293 MOAD: ic50=6.6mM
    BindingDB: Ki=7100nM, IC50=680000nM
    25 6wpg:A (2.283) BS01 SAL ? GO:0009862 ... Q5ICL9 32788727
    26 6wpg:B (2.283) BS01 SAL ? GO:0009862 ... Q5ICL9 32788727
    27 8b1s:A (1.6) BS01 SAL ? N/A Q5XX06 39100314
    28 8b2u:A (1.8) BS01 SAL ? N/A Q5XX06 39100314
    29 8vae:A (3.7) BS01 SAL N/A GO:0003677 ... P02768 38852682
    30 8vae:A (3.7) BS02 SAL N/A GO:0003677 ... P02768 38852682
    31 8vae:A (3.7) BS03 SAL N/A GO:0003677 ... P02768 38852682
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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