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BioLiP
Download all results in tab-seperated text for 24 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1err:A (2.6) BS01 RAL ? N/A P03372 9338790 PDBbind: -logKd/Ki=8.11, IC50=7.7nM
    BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    2 1err:B (2.6) BS01 RAL ? N/A P03372 9338790 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    3 1qkn:A (2.25) BS01 RAL ? N/A Q62986 10469641 PDBbind: -logKd/Ki=8.47, IC50=3.4nM
    4 2jfa:A (2.55) BS02 RAL ? N/A P03372 17283072 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    5 2jfa:B (2.55) BS02 RAL ? N/A P03372 17283072 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    6 2qxs:A (1.7) BS01 RAL ? N/A P03372 20924370 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    7 2qxs:B (1.7) BS01 RAL ? N/A P03372 20924370 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    8 2y05:A (2.2) BS02 RAL 1.3.1.48
    1.3.1.74    		 GO:0003824 ... Q14914 N/A
    9 2y05:A (2.2) BS03 RAL 1.3.1.48
    1.3.1.74    		 GO:0003824 ... Q14914 N/A
    10 2y05:B (2.2) BS01 RAL 1.3.1.48
    1.3.1.74    		 GO:0003824 ... Q14914 N/A
    11 7kbs:A (1.834) BS01 RAL ? N/A P03372 35575456 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    12 7kbs:B (1.834) BS01 RAL ? N/A P03372 35575456 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    13 7ndo:A (1.6) BS01 RAL ? N/A P03372 34006920 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    14 7ndo:B (1.6) BS01 RAL ? N/A P03372 34006920 BindingDB: IC50=1.8nM, EC50=2.4nM, Ki=0.37nM
    15 7opn:A (2.6) BS04 RAL 1.17.3.-
    1.2.3.1    		 GO:0004031 ... Q06278 34415167 BindingDB: IC50=8.0nM, Ki=2.3nM
    16 7opn:A (2.6) BS05 RAL 1.17.3.-
    1.2.3.1    		 GO:0004031 ... Q06278 34415167 BindingDB: IC50=8.0nM, Ki=2.3nM
    17 7opn:B (2.6) BS04 RAL 1.17.3.-
    1.2.3.1    		 GO:0004031 ... Q06278 34415167 BindingDB: IC50=8.0nM, Ki=2.3nM
    18 7opn:B (2.6) BS05 RAL 1.17.3.-
    1.2.3.1    		 GO:0004031 ... Q06278 34415167 BindingDB: IC50=8.0nM, Ki=2.3nM
    19 7orc:A (2.7) BS04 RAL 1.17.3.-
    1.2.3.1    		 GO:0004031 ... Q06278 34415167 BindingDB: IC50=8.0nM, Ki=2.3nM
    20 7orc:A (2.7) BS05 RAL 1.17.3.-
    1.2.3.1    		 GO:0004031 ... Q06278 34415167 BindingDB: IC50=8.0nM, Ki=2.3nM
    21 7orc:B (2.7) BS04 RAL 1.17.3.-
    1.2.3.1    		 GO:0004031 ... Q06278 34415167 BindingDB: IC50=8.0nM, Ki=2.3nM
    22 7orc:B (2.7) BS05 RAL 1.17.3.-
    1.2.3.1    		 GO:0004031 ... Q06278 34415167 BindingDB: IC50=8.0nM, Ki=2.3nM
    23 7ujc:A (1.78) BS01 RAL ? N/A P03372 35575456
    24 7ujc:B (1.78) BS01 RAL ? N/A P03372 35575456
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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