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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 164 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1a3w:A (3.0) BS01 PGA 2.7.1.40 GO:0000287 ... P00549 9519410
    2 1a3w:B (3.0) BS01 PGA 2.7.1.40 GO:0000287 ... P00549 9519410
    3 1a3x:A (3.0) BS01 PGA 2.7.1.40 GO:0000287 ... P00549 9519410
    4 1a3x:B (3.0) BS01 PGA 2.7.1.40 GO:0000287 ... P00549 9519410
    5 1amk:A (1.83) BS01 PGA 5.3.1.1 GO:0004807 ... P48499 10235625 MOAD: Ki=0.05mM
    PDBbind: -logKd/Ki=4.30, Ki=50uM
    6 1aw1:A (2.7) BS01 PGA 5.3.1.1 GO:0004807 ... P50921 9442062 PDBbind: -logKd/Ki=1.05, Ki=89mM
    7 1aw1:B (2.7) BS01 PGA 5.3.1.1 GO:0004807 ... P50921 9442062 PDBbind: -logKd/Ki=1.05, Ki=89mM
    8 1aw1:D (2.7) BS01 PGA 5.3.1.1 GO:0004807 ... P50921 9442062
    9 1aw1:E (2.7) BS01 PGA 5.3.1.1 GO:0004807 ... P50921 9442062
    10 1aw1:G (2.7) BS01 PGA 5.3.1.1 GO:0004807 ... P50921 9442062
    11 1aw1:H (2.7) BS01 PGA 5.3.1.1 GO:0004807 ... P50921 9442062
    12 1aw1:J (2.7) BS01 PGA 5.3.1.1 GO:0004807 ... P50921 9442062
    13 1aw1:K (2.7) BS01 PGA 5.3.1.1 GO:0004807 ... P50921 9442062
    14 1btm:A (2.8) BS01 PGA 5.3.1.1 GO:0004807 ... P00943 8580851
    15 1btm:B (2.8) BS01 PGA 5.3.1.1 GO:0004807 ... P00943 8580851
    16 1egh:A (2.0) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 10715115 MOAD: Ki=2uM
    PDBbind: -logKd/Ki=5.70, Ki=2uM
    17 1egh:B (2.0) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 10715115 MOAD: Ki=2uM
    18 1egh:C (2.0) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 10715115 MOAD: Ki=2uM
    19 1egh:D (2.0) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 10715115 MOAD: Ki=2uM
    20 1egh:E (2.0) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 10715115 MOAD: Ki=2uM
    21 1egh:F (2.0) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 10715115 MOAD: Ki=2uM
    PDBbind: -logKd/Ki=5.70, Ki=2uM
    22 1gg1:A (2.0) BS01 PGA 2.5.1.54 GO:0003849 ... P0AB91 10926516
    23 1gg1:B (2.0) BS01 PGA 2.5.1.54 GO:0003849 ... P0AB91 10926516
    24 1gg1:C (2.0) BS01 PGA 2.5.1.54 GO:0003849 ... P0AB91 10926516
    25 1gg1:D (2.0) BS01 PGA 2.5.1.54 GO:0003849 ... P0AB91 10926516
    26 1hti:B (2.8) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P60174 8061610 PDBbind: -logKd/Ki=5.13, Ki=7.4uM
    27 1kv5:A (1.65) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 11997014 MOAD: Ki=60uM
    PDBbind: -logKd/Ki=4.22, Ki=60uM
    28 1kv5:B (1.65) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 11997014 MOAD: Ki=60uM
    PDBbind: -logKd/Ki=4.22, Ki=60uM
    29 1lyx:A (1.9) BS01 PGA 5.3.1.1 GO:0004807 ... Q07412 12403619 MOAD: Ki=0.029mM
    PDBbind: -logKd/Ki=4.54, Ki=0.029mM
    30 1lzo:B (2.8) BS01 PGA 5.3.1.1 GO:0004807 ... Q07412 12403619 PDBbind: -logKd/Ki=4.54, Ki=0.029mM
    31 1lzo:D (2.8) BS01 PGA 5.3.1.1 GO:0004807 ... Q07412 12403619
    32 1ml1:A (2.6) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 9089815 PDBbind: -logKd/Ki=4.28, Ki=52uM
    33 1ml1:C (2.6) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 9089815
    34 1ml1:E (2.6) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 9089815
    35 1ml1:G (2.6) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 9089815
    36 1ml1:I (2.6) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 9089815
    37 1ml1:K (2.6) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 9089815
    38 1n55:A (0.83) BS01 PGA 5.3.1.1 GO:0004807 ... P48499 12522213
    39 1ofo:A (1.86) BS01 PGA 2.5.1.54 GO:0003849 ... P32449 15019786
    40 1ofo:B (1.86) BS01 PGA 2.5.1.54 GO:0003849 ... P32449 15019786
    41 1pdz:A (2.2) BS01 PGA 4.2.1.11 GO:0000015 ... P56252 7547999 MOAD: Ki=0.2mM
    PDBbind: -logKd/Ki=3.70, Ki=0.2mM
    42 1qds:A (2.0) BS01 PGA 5.3.1.1 GO:0004807 ... P48499 10785370 MOAD: Ki=0.048mM
    43 1s89:A (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    PDBbind: -logKd/Ki=5.24, Ki=5.8uM
    44 1s89:B (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    45 1s89:C (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    46 1s89:D (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    47 1s89:E (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    48 1s89:F (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    PDBbind: -logKd/Ki=5.24, Ki=5.8uM
    49 1s8a:A (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    50 1s8a:B (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    51 1s8a:C (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    52 1s8a:D (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    53 1s8a:E (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    54 1s8a:F (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    55 1ssg:A (2.9) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    56 1ssg:B (2.9) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    57 1su5:A (2.7) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    58 1su5:B (2.7) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    59 1sw0:A (1.71) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    60 1sw0:B (1.71) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    61 1sw3:A (2.03) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    62 1sw3:B (2.03) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    63 1sw7:A (2.22) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    64 1sw7:B (2.22) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    65 1te2:A (1.76) BS01 PGA 3.1.3.22
    3.1.3.23
    3.1.3.50
    3.1.3.68
    GO:0000287 ... P77247 N/A
    66 1te2:B (1.76) BS01 PGA 3.1.3.22
    3.1.3.23
    3.1.3.50
    3.1.3.68
    GO:0000287 ... P77247 N/A
    67 1tti:A (2.4) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 8591044
    68 2bkv:A (1.5) BS01 PGA 3.5.99.6 GO:0004342 ... O35000 15755726
    69 2bkv:B (1.5) BS01 PGA 3.5.99.6 GO:0004342 ... O35000 15755726
    70 2btm:A (2.4) BS01 PGA 5.3.1.1 GO:0004807 ... P00943 10383424
    71 2btm:B (2.4) BS01 PGA 5.3.1.1 GO:0004807 ... P00943 10383424
    72 2j27:A (1.15) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 17176070 MOAD: Ki=0.3mM
    PDBbind: -logKd/Ki=3.52, Ki=0.3mM
    73 2j27:B (1.15) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 17176070 MOAD: Ki=0.3mM
    PDBbind: -logKd/Ki=3.52, Ki=0.3mM
    74 2rka:A (1.95) BS01 PGA 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 18197707 MOAD: Ki=1mM
    PDBbind: -logKd/Ki=3.00, Ki=1mM
    75 2rka:C (1.95) BS01 PGA 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 18197707 MOAD: Ki=1mM
    76 2v2c:A (1.89) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 18219118 MOAD: Ki=0.39mM
    PDBbind: -logKd/Ki=3.41, Ki=0.39mM
    77 2v2h:A (1.18) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 18219118 MOAD: Ki=0.17mM
    PDBbind: -logKd/Ki=3.77, Ki=0.17mM
    78 2v2h:B (1.18) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 18219118 MOAD: Ki=0.17mM
    79 2v2h:C (1.18) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 18219118 MOAD: Ki=0.17mM
    80 2vel:A (2.3) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 18239072
    81 2vel:B (2.3) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 18239072
    82 2vgb:A (2.73) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    83 2vgb:B (2.73) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    84 2vgb:C (2.73) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    85 2vgb:D (2.73) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    86 2vgf:A (2.75) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    87 2vgf:B (2.75) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    88 2vgf:C (2.75) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    89 2vgf:D (2.75) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    90 2vgg:A (2.74) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    91 2vgg:B (2.74) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    92 2vgg:C (2.74) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    93 2vgg:D (2.74) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    94 2vgi:A (2.87) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    95 2vgi:B (2.87) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    96 2vgi:C (2.87) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    97 2vgi:D (2.87) BS02 PGA 2.7.1.40 GO:0000287 ... P30613 11960989
    98 2vxn:A (0.82) BS02 PGA 5.3.1.1 GO:0004807 ... P48499 20235230
    99 2ypi:A (2.5) BS01 PGA 5.3.1.1 GO:0004807 ... P00942 2204418 MOAD: Ki=15uM
    PDBbind: -logKd/Ki=4.82, Ki=15uM
    100 2ypi:B (2.5) BS01 PGA 5.3.1.1 GO:0004807 ... P00942 2204418 MOAD: Ki=15uM
    PDBbind: -logKd/Ki=4.82, Ki=15uM
    101 3dtb:A (1.3) BS01 PGA 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 18772387
    102 3dtb:B (1.3) BS01 PGA 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 18772387
    103 3moh:A (2.1) BS03 PGA 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 20476774 MOAD: Ki=1460uM
    PDBbind: -logKd/Ki=2.84, Ki=1460uM
    104 3moh:B (2.1) BS03 PGA 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 20476774 MOAD: Ki=1460uM
    105 3pvf:A (1.73) BS01 PGA 5.3.1.1 GO:0004807 ... Q07412 21447068
    106 4bi6:A (1.45) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P36186 23894402 MOAD: Kd=113.3uM
    PDBbind: -logKd/Ki=3.95, Kd=113.3uM
    107 4bi7:A (1.6) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P36186 23894402 MOAD: Kd=26.4uM
    PDBbind: -logKd/Ki=4.58, Kd=26.4uM
    108 4ff7:A (1.86) BS01 PGA 5.3.1.1 GO:0004807 ... P00942 22949845
    109 4og8:A (1.53) BS03 PGA ? GO:0005634 ... O00255 24472025
    110 5eyw:A (1.7) BS01 PGA 5.3.1.1 GO:0004807 ... K0E682 27614148
    111 5eyw:B (1.7) BS01 PGA 5.3.1.1 GO:0004807 ... K0E682 27614148
    112 5fh5:A (1.55) BS03 PGA 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 26709450
    113 5gv4:A (2.09) BS01 PGA 5.3.1.1 GO:0004807 ... Q07412 N/A
    114 5gzp:A (2.03) BS01 PGA 5.3.1.1 GO:0004807 ... Q07412 N/A
    115 5gzp:B (2.03) BS01 PGA 5.3.1.1 GO:0004807 ... Q07412 N/A
    116 5i3h:B (2.25) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 27149328 MOAD: Ki=120uM
    117 5i3i:A (2.2) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 27149328 MOAD: Ki=2.6mM
    118 5i3i:B (2.2) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 27149328 MOAD: Ki=2.6mM
    119 5i3i:C (2.2) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 27149328 MOAD: Ki=2.6mM
    120 5i3i:D (2.2) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 27149328 MOAD: Ki=2.6mM
    121 5i3k:B (2.209) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 27149328 MOAD: Ki=12uM
    122 5i3k:C (2.209) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 27149328 MOAD: Ki=12uM
    123 5i3k:D (2.209) BS01 PGA 5.3.1.1 GO:0004807 ... P04789 27149328 MOAD: Ki=12uM
    124 5v9h:A (2.15) BS04 PGA 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 28345895
    125 5v9h:B (2.15) BS03 PGA 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 28345895
    126 5wn2:A (2.288) BS04 PGA 3.1.11.2
    3.1.21.-
    GO:0003677 ... P27695 29374164
    127 5y2w:A (2.2) BS01 PGA ? N/A P73862 29279392 MOAD: Kd=0.43mM
    128 6bve:A (1.78) BS01 PGA 5.3.1.1 GO:0004807 ... Q59994 30538993
    129 6bve:B (1.78) BS01 PGA 5.3.1.1 GO:0004807 ... Q59994 30538993
    130 6enl:A (2.2) BS01 PGA 4.2.1.11 GO:0000015 ... P00924 2007121
    131 6mgi:A (2.986) BS03 PGA 4.1.1.31 GO:0003824 ... P04711 32459324
    132 6mgi:B (2.986) BS04 PGA 4.1.1.31 GO:0003824 ... P04711 32459324
    133 6oog:A (2.02) BS01 PGA 5.3.1.1 GO:0004807 ... Q9GTX8 31923219
    134 6ooi:A (2.14) BS01 PGA 5.3.1.1 GO:0004807 ... P48501 31923219
    135 6ooi:B (2.14) BS01 PGA 5.3.1.1 GO:0004807 ... P48501 31923219
    136 6ooi:C (2.14) BS01 PGA 5.3.1.1 GO:0004807 ... P48501 31923219
    137 6ooi:D (2.14) BS01 PGA 5.3.1.1 GO:0004807 ... P48501 31923219
    138 6ooi:E (2.14) BS01 PGA 5.3.1.1 GO:0004807 ... P48501 31923219
    139 6ooi:F (2.14) BS01 PGA 5.3.1.1 GO:0004807 ... P48501 31923219
    140 6ooi:G (2.14) BS01 PGA 5.3.1.1 GO:0004807 ... P48501 31923219
    141 6ooi:H (2.14) BS01 PGA 5.3.1.1 GO:0004807 ... P48501 31923219
    142 6pfk:A (2.6) BS01 PGA 2.7.1.11 GO:0003872 ... P00512 2136935
    143 6pfk:A (2.6) BS02 PGA 2.7.1.11 GO:0003872 ... P00512 2136935
    144 6pfk:B (2.6) BS01 PGA 2.7.1.11 GO:0003872 ... P00512 2136935
    145 6pfk:B (2.6) BS02 PGA 2.7.1.11 GO:0003872 ... P00512 2136935
    146 6pfk:C (2.6) BS01 PGA 2.7.1.11 GO:0003872 ... P00512 2136935
    147 6pfk:C (2.6) BS02 PGA 2.7.1.11 GO:0003872 ... P00512 2136935
    148 6pfk:D (2.6) BS01 PGA 2.7.1.11 GO:0003872 ... P00512 2136935
    149 6pfk:D (2.6) BS02 PGA 2.7.1.11 GO:0003872 ... P00512 2136935
    150 6up5:B (1.92) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P60174 32585311
    151 6upf:A (1.65) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P60174 32585311
    152 6upf:B (1.65) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P60174 32585311
    153 7abx:A (1.2) BS01 PGA 5.3.1.1 GO:0004807 ... P48499 34258011
    154 7az3:A (1.15) BS01 PGA 5.3.1.1 GO:0004807 ... P48499 34258011
    155 7az4:A (1.15) BS01 PGA 5.3.1.1 GO:0004807 ... P48499 34258011
    156 7n3r:B (2.25) BS01 PGA 5.4.2.11
    5.4.2.4
    GO:0003824 ... P07738 35362470
    157 7n3s:A (2.48) BS01 PGA 5.4.2.11
    5.4.2.4
    GO:0003824 ... P07738 35362470
    158 7n3s:A (2.48) BS02 PGA 5.4.2.11
    5.4.2.4
    GO:0003824 ... P07738 35362470
    159 7n3s:B (2.48) BS01 PGA 5.4.2.11
    5.4.2.4
    GO:0003824 ... P07738 35362470
    160 7t0q:A (2.0) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P60174 N/A
    161 7thi:A (1.33) BS01 PGA 5.4.2.11
    5.4.2.4
    GO:0003824 ... P07738 N/A
    162 7thi:B (1.33) BS01 PGA 5.4.2.11
    5.4.2.4
    GO:0003824 ... P07738 N/A
    163 7uxv:A (2.15) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P60174 N/A
    164 7uxv:B (2.15) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P60174 N/A

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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