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BioLiP
Download all results in tab-seperated text for 215 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1bxh:A (2.75) BS01 MMA ? GO:0030246 ... P02866 10336986
    2 1bxh:B (2.75) BS01 MMA ? GO:0030246 ... P02866 10336986
    3 1bxh:C (2.75) BS01 MMA ? GO:0030246 ... P02866 10336986
    4 1dgl:B (2.4) BS01 MMA ? GO:0005537 ... P08902 9830028
    5 1j4u:A (2.9) BS01 MMA ? GO:0030246 ... Q7M1T4 11902840
    6 1j4u:B (2.9) BS01 MMA ? GO:0030246 ... Q7M1T4 11902840
    7 1j4u:C (2.9) BS01 MMA ? GO:0030246 ... Q7M1T4 11902840
    8 1j4u:D (2.9) BS01 MMA ? GO:0030246 ... Q7M1T4 11902840
    9 1kiu:B (3.0) BS01 MMA ? GO:0005515 ... P08191 12010488
    10 1kiu:D (3.0) BS01 MMA ? GO:0005515 ... P08191 12010488
    11 1kiu:F (3.0) BS01 MMA ? GO:0005515 ... P08191 12010488
    12 1kiu:H (3.0) BS01 MMA ? GO:0005515 ... P08191 12010488
    13 1kiu:J (3.0) BS01 MMA ? GO:0005515 ... P08191 12010488
    14 1kiu:L (3.0) BS01 MMA ? GO:0005515 ... P08191 12010488
    15 1kiu:N (3.0) BS01 MMA ? GO:0005515 ... P08191 12010488
    16 1kiu:P (3.0) BS01 MMA ? GO:0005515 ... P08191 12010488
    17 1kuj:A (2.0) BS04 MMA ? GO:0005575 ... P18670 11988090
    18 1kuj:C (2.0) BS04 MMA ? GO:0005575 ... P18670 11988090
    19 1kuj:E (2.0) BS04 MMA ? GO:0005575 ... P18670 11988090
    20 1kuj:G (2.0) BS04 MMA ? GO:0005575 ... P18670 11988090
    21 1kwu:A (1.95) BS01 MMA ? N/A P19999 11850428
    22 1kwu:B (1.95) BS01 MMA ? N/A P19999 11850428
    23 1kwu:C (1.95) BS01 MMA ? N/A P19999 11850428
    24 1lob:A (2.0) BS03 MMA ? GO:0005515 ... P04122 2091026
    25 1lob:B (2.0) BS01 MMA ? GO:0005537 ... P12306 2091026
    26 1lob:C (2.0) BS01 MMA ? GO:0005515 ... P04122 2091026
    27 1lob:D (2.0) BS01 MMA ? GO:0005537 ... P12306 2091026
    28 1lob:E (2.0) BS01 MMA ? GO:0005515 ... P04122 2091026
    29 1lob:F (2.0) BS01 MMA ? GO:0005537 ... P12306 2091026
    30 1lob:G (2.0) BS01 MMA ? GO:0005515 ... P04122 2091026
    31 1lob:H (2.0) BS01 MMA ? GO:0005537 ... P12306 2091026
    32 1mfd:H (2.1) BS01 MMA N/A N/A N/A 8172893 PDBbind: -logKd/Ki=5.31, Kd=4.9uM
    33 1msa:A (2.29) BS01 MMA ? N/A P30617 7664110
    34 1msa:A (2.29) BS02 MMA ? N/A P30617 7664110
    35 1msa:A (2.29) BS03 MMA ? N/A P30617 7664110
    36 1msa:A (2.29) BS04 MMA ? N/A P30617 7664110
    37 1msa:B (2.29) BS01 MMA ? N/A P30617 7664110
    38 1msa:B (2.29) BS02 MMA ? N/A P30617 7664110
    39 1msa:B (2.29) BS03 MMA ? N/A P30617 7664110
    40 1msa:B (2.29) BS04 MMA ? N/A P30617 7664110
    41 1msa:C (2.29) BS01 MMA ? N/A P30617 7664110
    42 1msa:C (2.29) BS02 MMA ? N/A P30617 7664110
    43 1msa:C (2.29) BS03 MMA ? N/A P30617 7664110
    44 1msa:C (2.29) BS04 MMA ? N/A P30617 7664110
    45 1msa:D (2.29) BS01 MMA ? N/A P30617 7664110
    46 1msa:D (2.29) BS02 MMA ? N/A P30617 7664110
    47 1msa:D (2.29) BS03 MMA ? N/A P30617 7664110
    48 1msa:D (2.29) BS04 MMA ? N/A P30617 7664110
    49 1mvq:A (1.77) BS01 MMA ? GO:0030246 ... P83721 12966038
    50 1niv:A (3.0) BS01 MMA ? N/A P30617 8893860
    51 1niv:A (3.0) BS02 MMA ? N/A P30617 8893860
    52 1niv:A (3.0) BS03 MMA ? N/A P30617 8893860
    53 1niv:C (3.0) BS01 MMA ? N/A P30617 8893860
    54 1niv:C (3.0) BS02 MMA ? N/A P30617 8893860
    55 1niv:C (3.0) BS03 MMA ? N/A P30617 8893860
    56 1ona:B (2.35) BS01 MMA ? GO:0030246 ... P02866 8940035
    57 1q8o:A (2.2) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    58 1q8o:B (2.2) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    59 1q8p:A (1.75) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    60 1q8p:B (1.75) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    61 1q8q:A (2.05) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    62 1q8q:B (2.05) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    63 1q8s:B (2.05) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    64 1qdc:A (2.0) BS01 MMA ? GO:0005537 ... P55915 10506175
    65 1qdc:B (2.0) BS01 MMA ? GO:0005537 ... P55915 10506175
    66 1qdc:C (2.0) BS01 MMA ? GO:0005537 ... P55915 10506175
    67 1qdc:D (2.0) BS01 MMA ? GO:0005537 ... P55915 10506175
    68 1rdl:1 (1.7) BS01 MMA ? N/A P08661 8557671 MOAD: Ki=5.7mM
    PDBbind: -logKd/Ki=2.24, Ki=5.7mM
    69 1rdl:2 (1.7) BS01 MMA ? N/A P08661 8557671 MOAD: Ki=5.7mM
    70 1rdm:1 (1.9) BS01 MMA ? N/A P08661 8557671 MOAD: Ki=5.7mM
    71 1rdm:1 (1.9) BS02 MMA ? N/A P08661 8557671 MOAD: Ki=5.7mM
    72 1rdm:2 (1.9) BS01 MMA ? N/A P08661 8557671 MOAD: Ki=5.7mM
    73 1s1a:A (1.8) BS01 MMA ? GO:0030246 ... Q8GSD2 N/A
    74 1s4p:A (2.01) BS01 MMA 2.4.1.- GO:0000030 ... P27809 14752117
    75 1s4p:B (2.01) BS01 MMA 2.4.1.- GO:0000030 ... P27809 14752117
    76 1ukg:A (1.7) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    77 1ukg:B (1.7) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    78 1uqx:A (1.7) BS03 MMA ? GO:0046872 ... Q8XUA5 15101976
    79 1ws5:A (1.9) BS04 MMA ? GO:0005575 ... P18670 15733927 MOAD: Ka=0.00108M^-1
    80 1ws5:C (1.9) BS04 MMA ? GO:0005575 ... P18670 15733927 MOAD: Ka=0.00108M^-1
    81 1ws5:E (1.9) BS04 MMA ? GO:0005575 ... P18670 15733927 MOAD: Ka=0.00108M^-1
    82 1ws5:G (1.9) BS04 MMA ? GO:0005575 ... P18670 15733927 MOAD: Ka=0.00108M^-1
    83 1x1v:A (2.45) BS01 MMA ? GO:0030246 ... Q8L5H4 15958419
    84 1x1v:A (2.45) BS02 MMA ? GO:0030246 ... Q8L5H4 15958419
    85 1x1v:A (2.45) BS03 MMA ? GO:0030246 ... Q8L5H4 15958419
    86 1x1v:B (2.45) BS01 MMA ? GO:0030246 ... Q8L5H4 15958419
    87 1x1v:B (2.45) BS02 MMA ? GO:0030246 ... Q8L5H4 15958419
    88 2auy:A (1.95) BS01 MMA ? GO:0030246 ... Q8GSD2 16704415
    89 2auy:B (1.95) BS01 MMA ? GO:0030246 ... Q8GSD2 16704415
    90 2bmz:A (2.4) BS01 MMA ? GO:0030246 ... O22321 15944373
    91 2bmz:A (2.4) BS02 MMA ? GO:0030246 ... O22321 15944373
    92 2bmz:B (2.4) BS01 MMA ? GO:0030246 ... O22321 15944373
    93 2bmz:B (2.4) BS02 MMA ? GO:0030246 ... O22321 15944373
    94 2bv4:A (1.0) BS03 MMA ? GO:0046872 ... Q7NX84 16768446 MOAD: ic50=600uM
    95 2bv4:B (1.0) BS03 MMA ? GO:0046872 ... Q7NX84 16768446 MOAD: ic50=600uM
    96 2d7f:A (2.31) BS01 MMA ? GO:0030246 ... P14894 17683532
    97 2d7f:F (2.31) BS01 MMA ? GO:0030246 ... P14894 17683532
    98 2d7f:L (2.31) BS01 MMA ? GO:0030246 ... P14894 17683532
    99 2d7f:S (2.31) BS01 MMA ? GO:0030246 ... P14894 17683532
    100 2ef6:A (2.1) BS01 MMA ? GO:0030246 ... P14894 17881248
    101 2ef6:B (2.1) BS01 MMA ? GO:0030246 ... P14894 17881248
    102 2ef6:C (2.1) BS01 MMA ? GO:0030246 ... P14894 17881248
    103 2ef6:D (2.1) BS01 MMA ? GO:0030246 ... P14894 17881248
    104 2g93:A (1.9) BS01 MMA 3.4.21.- GO:0005576 ... P24627 N/A
    105 2gn3:B (1.97) BS01 MMA ? GO:0030246 ... Q8GSD2 16824540
    106 2gnd:A (2.25) BS01 MMA ? GO:0030246 ... Q8GSD2 16824540
    107 2jdn:B (1.3) BS01 MMA ? GO:0030246 ... Q9HYN5 17540045 MOAD: Kd=2.78uM
    108 2jdn:C (1.3) BS01 MMA ? GO:0030246 ... Q9HYN5 17540045 MOAD: Kd=2.78uM
    109 2jdn:D (1.3) BS01 MMA ? GO:0030246 ... Q9HYN5 17540045 MOAD: Kd=2.78uM
    110 2jdy:A (1.7) BS01 MMA ? GO:0030246 ... Q9HYN5 17540045 MOAD: Kd=42.9uM
    111 2jdy:B (1.7) BS01 MMA ? GO:0030246 ... Q9HYN5 17540045 MOAD: Kd=42.9uM
    112 2jdy:C (1.7) BS01 MMA ? GO:0030246 ... Q9HYN5 17540045 MOAD: Kd=42.9uM
    113 2jdy:D (1.7) BS01 MMA ? GO:0030246 ... Q9HYN5 17540045 MOAD: Kd=42.9uM
    114 2ovu:A (1.5) BS01 MMA ? GO:0030246 ... P14894 17881248
    115 2ow4:A (1.6) BS01 MMA ? GO:0030246 ... P81364 17881248
    116 2ri9:A (1.95) BS01 MMA 3.2.1.113 GO:0004571 ... P31723 18323617
    117 2ri9:B (1.95) BS01 MMA 3.2.1.113 GO:0004571 ... P31723 18323617
    118 2vnv:A (1.7) BS01 MMA ? GO:0046872 ... B4EH87 18215132 MOAD: Kd=2.75uM
    119 2vnv:B (1.7) BS01 MMA ? GO:0046872 ... B4EH87 18215132 MOAD: Kd=2.75uM
    120 2vnv:C (1.7) BS01 MMA ? GO:0046872 ... B4EH87 18215132 MOAD: Kd=2.75uM
    121 2vnv:D (1.7) BS01 MMA ? GO:0046872 ... B4EH87 18215132 MOAD: Kd=2.75uM
    122 2vnv:E (1.7) BS01 MMA ? GO:0046872 ... B4EH87 18215132 MOAD: Kd=2.75uM
    123 3a0d:A (2.2) BS01 MMA ? N/A Q8L568 20546901
    124 3g81:A (1.8) BS04 MMA ? N/A P35247 19249874
    125 3g81:B (1.8) BS04 MMA ? N/A P35247 19249874
    126 3g81:C (1.8) BS04 MMA ? N/A P35247 19249874
    127 3m7j:A (2.26) BS01 MMA ? N/A Q8GEJ9 23468636
    128 3m7j:B (2.26) BS01 MMA ? N/A Q8GEJ9 23468636
    129 3paq:A (2.1) BS03 MMA ? N/A P08427 21047777
    130 3r51:A (2.1) BS01 MMA ? GO:0002213 ... P93193 22808208 MOAD: Kd=142uM
    131 3vzf:A (2.8) BS01 MMA ? GO:0005515 ... O60844 24790092
    132 3zdv:A (1.41) BS03 MMA ? GO:0030246 ... Q9HYN5 23719508 PDBbind: -logKd/Ki=5.48, Kd=3.3uM
    133 3zdv:B (1.41) BS03 MMA ? GO:0030246 ... Q9HYN5 23719508 PDBbind: -logKd/Ki=5.48, Kd=3.3uM
    134 3zdv:C (1.41) BS03 MMA ? GO:0030246 ... Q9HYN5 23719508
    135 3zdv:D (1.41) BS03 MMA ? GO:0030246 ... Q9HYN5 23719508
    136 4eem:A (2.2) BS01 MMA 2.4.1.-
    2.4.1.22
    2.4.1.275
    2.4.1.38
    2.4.1.90    		 GO:0005975 ... P15291 22740701
    137 4gx7:A (2.85) BS01 MMA ? N/A P09545 23274141
    138 4gx7:B (2.85) BS01 MMA ? N/A P09545 23274141
    139 4gx7:C (2.85) BS01 MMA ? N/A P09545 23274141
    140 4gx7:D (2.85) BS01 MMA ? N/A P09545 23274141
    141 4gx7:D (2.85) BS02 MMA ? N/A P09545 23274141
    142 4gx7:E (2.85) BS01 MMA ? N/A P09545 23274141
    143 4gx7:F (2.85) BS01 MMA ? N/A P09545 23274141
    144 4h0i:A (2.4) BS01 MMA N/A N/A N/A 23733869
    145 4k1y:A (2.5) BS01 MMA ? GO:0005537 ... A0A023GPI8 24865454
    146 4k1y:B (2.5) BS01 MMA ? GO:0005537 ... A0A023GPI8 24865454
    147 4k1y:C (2.5) BS01 MMA ? GO:0005537 ... A0A023GPI8 24865454
    148 4k1z:D (2.3) BS01 MMA ? GO:0005537 ... A0A023GPI8 24865454
    149 4mq0:A (2.12) BS01 MMA N/A GO:0030246 ... N/A N/A
    150 4mq0:A (2.12) BS02 MMA N/A GO:0030246 ... N/A N/A
    151 4mq0:A (2.12) BS03 MMA N/A GO:0030246 ... N/A N/A
    152 4n37:A (2.0) BS01 MMA ? N/A Q9UJ71 24217250
    153 4n37:B (2.0) BS01 MMA ? N/A Q9UJ71 24217250
    154 4n37:C (2.0) BS01 MMA ? N/A Q9UJ71 24217250
    155 4n37:D (2.0) BS01 MMA ? N/A Q9UJ71 24217250
    156 4oiz:A (3.4) BS01 MMA ? N/A A0QYH7 24957055
    157 4oiz:B (3.4) BS01 MMA ? N/A A0QYH7 24957055
    158 4oiz:B (3.4) BS02 MMA ? N/A A0QYH7 24957055
    159 4oiz:B (3.4) BS03 MMA ? N/A A0QYH7 24957055
    160 4oiz:C (3.4) BS01 MMA ? N/A A0QYH7 24957055
    161 4oiz:C (3.4) BS02 MMA ? N/A A0QYH7 24957055
    162 4oiz:C (3.4) BS03 MMA ? N/A A0QYH7 24957055
    163 4oiz:E (3.4) BS01 MMA ? N/A A0QYH7 24957055
    164 4zes:A (1.65) BS01 MMA ? N/A Q8WTT0 25995448 MOAD: Ki=9.4mM
    165 4zes:B (1.65) BS01 MMA ? N/A Q8WTT0 25995448 MOAD: Ki=9.4mM
    166 5a3o:A (1.6) BS03 MMA ? GO:0030246 ... Q9HYN5 27308201 PDBbind: -logKd/Ki=4.73, Kd=18.5uM
    167 5a3o:B (1.6) BS03 MMA ? GO:0030246 ... Q9HYN5 27308201 PDBbind: -logKd/Ki=4.73, Kd=18.5uM
    168 5a3o:C (1.6) BS03 MMA ? GO:0030246 ... Q9HYN5 27308201
    169 5a3o:D (1.6) BS03 MMA ? GO:0030246 ... Q9HYN5 27308201
    170 5cna:A (2.0) BS01 MMA ? GO:0030246 ... P02866 15299352
    171 5cna:B (2.0) BS01 MMA ? GO:0030246 ... P02866 15299352
    172 5cna:C (2.0) BS01 MMA ? GO:0030246 ... P02866 15299352
    173 5cna:D (2.0) BS01 MMA ? GO:0030246 ... P02866 15299352
    174 5eyx:A (2.25) BS01 MMA ? GO:0005537 ... C0HJX1 26946944
    175 5eyx:B (2.25) BS01 MMA ? GO:0005537 ... C0HJX1 26946944
    176 5eyy:A (1.902) BS01 MMA ? GO:0005537 ... C0HJX1 26946944
    177 5f5q:A (2.52) BS03 MMA ? GO:0005509 ... C0HJY1 27737777
    178 5f5q:B (2.52) BS03 MMA ? GO:0005509 ... C0HJY1 27737777
    179 5jcq:A (1.602) BS01 MMA ? GO:0007155 ... P08191 N/A
    180 5jcq:B (1.602) BS01 MMA ? GO:0007155 ... P08191 N/A
    181 5jcr:A (1.701) BS01 MMA ? GO:0007155 ... P08191 N/A
    182 5jcr:B (1.701) BS01 MMA ? GO:0007155 ... P08191 N/A
    183 5u38:A (1.6) BS01 MMA ? GO:0030246 ... G1EUI6 28867234
    184 5u3e:A (2.3) BS01 MMA ? GO:0030246 ... P58906 28803976
    185 6flz:A (1.895) BS01 MMA ? GO:0030246 ... Q53J09 30065388
    186 6flz:A (1.895) BS02 MMA ? GO:0030246 ... Q53J09 30065388
    187 6flz:B (1.895) BS01 MMA ? GO:0030246 ... Q53J09 30065388
    188 6fwg:A (1.07) BS01 MMA ? GO:0004559 ... D6D1V7 32490192
    189 6gtz:A (1.719) BS02 MMA ? GO:0007155 ... A0A0R4I961 30543411
    190 6gtz:C (1.719) BS02 MMA ? GO:0007155 ... A0A0R4I961 30543411
    191 6gu0:A (2.501) BS02 MMA ? GO:0007155 ... A0A0R4I961 30543411
    192 6pws:A (1.0) BS03 MMA ? N/A E1BIQ4 31488546 MOAD: Ki=1.6mM
    193 6zfn:AAA (1.1) BS01 MMA 3.2.1.130 GO:0016798 ... Q5SRI9 33154157
    194 6zj1:AAA (1.957) BS01 MMA 3.2.1.130 GO:0016798 ... Q5SRI9 33154157
    195 7jub:A (1.2) BS02 MMA ? N/A P22897 33545173
    196 7juc:A (1.4) BS02 MMA ? N/A P22897 33545173
    197 7jud:A (1.4) BS03 MMA ? N/A P22897 33545173
    198 7jud:B (1.4) BS02 MMA ? N/A P22897 33545173
    199 7mgb:A (2.45) BS01 MMA ? GO:0030246 ... P02866 34096291
    200 7mgb:B (2.45) BS01 MMA ? GO:0030246 ... P02866 34096291
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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