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BioLiP
Download all results in tab-seperated text for 14 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1jt1:A (1.78) BS03 MCO 3.5.2.6 N/A Q9K578 12507470 MOAD: Ki=400uM
    PDBbind: -logKd/Ki=3.40, Ki=400uM
    2 1m2x:A (1.5) BS04 MCO 3.5.2.6 GO:0008270 ... O08498 12684522 MOAD: Ki~85uM
    PDBbind: -logKd/Ki=4.15, Ki=70uM
    3 1m2x:B (1.5) BS04 MCO 3.5.2.6 GO:0008270 ... O08498 12684522 MOAD: Ki~85uM
    4 1m2x:C (1.5) BS04 MCO 3.5.2.6 GO:0008270 ... O08498 12684522 MOAD: Ki~85uM
    5 1m2x:D (1.5) BS04 MCO 3.5.2.6 GO:0008270 ... O08498 12684522 MOAD: Ki~85uM
    6 1uzf:A (2.0) BS02 MCO 3.4.15.1 GO:0006508 ... P12821 15236580
    7 2fu8:A (1.8) BS03 MCO 3.5.2.6 GO:0008270 ... P52700 17999929 MOAD: Ki=20uM
    PDBbind: -logKd/Ki=4.70, Ki=20uM
    8 2fu8:B (1.8) BS03 MCO 3.5.2.6 GO:0008270 ... P52700 17999929 MOAD: Ki=20uM
    9 2qds:A (1.66) BS02 MCO 3.5.2.6 GO:0008270 ... P26918 18563261 MOAD: Ki=72uM
    10 4c1c:A (1.18) BS01 MCO 3.5.2.6 GO:0008270 ... P04190 26482303 PDBbind: -logKd/Ki=4.97, IC50=10.7uM
    11 4c1e:A (1.399) BS01 MCO 3.5.2.6 GO:0016787 ... Q9K2N0 26482303 PDBbind: -logKd/Ki=7.14, IC50=0.072uM
    12 4c1e:B (1.399) BS01 MCO 3.5.2.6 GO:0016787 ... Q9K2N0 26482303
    13 4c1g:A (1.714) BS03 MCO 3.5.2.6 GO:0008270 ... P52699 26482303 PDBbind: -logKd/Ki=5.14, IC50=7.2uM
    14 5zj2:A (1.1) BS03 MCO 3.5.2.6 GO:0008270 ... C7C422 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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