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BioLiP Library
Download all results in tab-seperated text for 23 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1mt5:A (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    2 1mt5:B (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    3 1mt5:C (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    4 1mt5:D (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    5 1mt5:E (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    6 1mt5:F (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    7 1mt5:G (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    8 1mt5:H (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    9 1mt5:I (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    10 1mt5:J (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    11 1mt5:K (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    12 1mt5:L (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    13 1mt5:M (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    14 1mt5:N (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    15 1mt5:O (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    16 1mt5:P (2.8) BS01 MAY 3.1.1.-
    3.5.1.99    		 GO:0000139 ... P97612 12459591 BindingDB: IC50=2.5nM
    17 4pkb:A (2.09) BS01 MAY 3.1.1.- GO:0006629 ... Q8LPW4 25248161 PDBbind: -logKd/Ki=6.94, IC50=0.116uM
    18 4x95:A (3.08) BS01 MAY 2.3.1.-
    3.1.1.32
    3.1.1.4
    3.1.1.5    		 GO:0004622 ... Q8NCC3 25727495
    19 4x95:B (3.08) BS01 MAY 2.3.1.-
    3.1.1.32
    3.1.1.4
    3.1.1.5    		 GO:0004622 ... Q8NCC3 25727495
    20 4x97:A (2.65) BS01 MAY 2.3.1.-
    3.1.1.32
    3.1.1.4
    3.1.1.5    		 GO:0004622 ... Q8NCC3 25727495
    21 4x97:B (2.65) BS01 MAY 2.3.1.-
    3.1.1.32
    3.1.1.4
    3.1.1.5    		 GO:0004622 ... Q8NCC3 25727495
    22 4x97:C (2.65) BS01 MAY 2.3.1.-
    3.1.1.32
    3.1.1.4
    3.1.1.5    		 GO:0004622 ... Q8NCC3 25727495
    23 4x97:D (2.65) BS01 MAY 2.3.1.-
    3.1.1.32
    3.1.1.4
    3.1.1.5    		 GO:0004622 ... Q8NCC3 25727495
    Reference:
    • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
    • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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