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BioLiP
Download all results in tab-seperated text for 5 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1e7v:A (2.4) BS01 LY2 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... O02697 11090628
    2 1yi3:A (2.5) BS01 LY2 2.7.11.1 GO:0004672 ... P11309 15657054 MOAD: ic50=4uM
    PDBbind: -logKd/Ki=5.40, IC50=4.0uM
    BindingDB: IC50=820nM
    3 4azt:A (2.34) BS02 LY2 2.1.1.294
    2.7.1.181    		 GO:0004672 ... Q47592 22970759 MOAD: ic50=68uM
    PDBbind: -logKd/Ki=4.17, IC50=68uM
    4 4cfk:A (1.55) BS01 LY2 ? N/A O60885 24533473 MOAD: Kd=1.83uM
    BindingDB: IC50=12400nM
    5 6g0d:A (1.314) BS01 LY2 ? N/A O60885 N/A BindingDB: IC50=12400nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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