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BioLiP
Download all results in tab-seperated text for 16 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2i4w:A (1.55) BS01 KGQ 3.4.23.16 GO:0004190 ... O92139 16979654 PDBbind: -logKd/Ki=11.59, Ki=2.6pM
    2 2i4w:B (1.55) BS01 KGQ 3.4.23.16 GO:0004190 ... O92139 16979654 MOAD: Ki=2.6pM
    PDBbind: -logKd/Ki=11.59, Ki=2.6pM
    3 2i4x:A (1.55) BS01 KGQ 3.4.23.16 GO:0004190 ... Q903J0 16979654 PDBbind: -logKd/Ki=11.72, Ki=1.9pM
    4 2i4x:B (1.55) BS01 KGQ 3.4.23.16 GO:0004190 ... Q903J0 16979654 MOAD: Ki=1.9pM
    PDBbind: -logKd/Ki=11.72, Ki=1.9pM
    5 4m8x:A (2.05) BS01 KGQ 3.1.26.13 GO:0004190 ... Q90JJ9 24371077 PDBbind: -logKd/Ki=10.20, Ki=0.063nM
    6 4m8x:A (2.05) BS02 KGQ 3.1.26.13 GO:0004190 ... Q90JJ9 24371077 PDBbind: -logKd/Ki=10.20, Ki=0.063nM
    7 4m8x:B (2.05) BS01 KGQ 3.1.26.13 GO:0004190 ... Q90JJ9 24371077 MOAD: Ki=0.063nM
    PDBbind: -logKd/Ki=10.20, Ki=0.063nM
    8 4m8x:B (2.05) BS02 KGQ 3.1.26.13 GO:0004190 ... Q90JJ9 24371077 MOAD: Ki=0.063nM
    PDBbind: -logKd/Ki=10.20, Ki=0.063nM
    9 4m8y:A (2.22) BS01 KGQ 3.1.26.13 GO:0004190 ... Q90JJ9 24371077 MOAD: Ki=0.11nM
    PDBbind: -logKd/Ki=9.96, Ki=0.11nM
    10 4m8y:A (2.22) BS02 KGQ 3.1.26.13 GO:0004190 ... Q90JJ9 24371077 MOAD: Ki=0.11nM
    PDBbind: -logKd/Ki=9.96, Ki=0.11nM
    11 4m8y:B (2.22) BS01 KGQ 3.1.26.13 GO:0004190 ... Q90JJ9 24371077 PDBbind: -logKd/Ki=9.96, Ki=0.11nM
    12 4m8y:B (2.22) BS02 KGQ 3.1.26.13 GO:0004190 ... Q90JJ9 24371077 PDBbind: -logKd/Ki=9.96, Ki=0.11nM
    13 7le7:A (1.978) BS01 KGQ 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12497 N/A
    14 7le7:B (1.978) BS01 KGQ 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12497 N/A
    15 7mab:A (1.879) BS01 KGQ 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12497 N/A
    16 7mab:B (1.879) BS01 KGQ 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12497 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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