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BioLiP
Download all results in tab-seperated text for 168 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1btn:A (2.0) BS01 I3P ? GO:0005543 ... Q62261 7588597 MOAD: Kd=40uM
    PDBbind: -logKd/Ki=4.40, Kd=40uM
    2 1djx:A (2.3) BS03 I3P 3.1.4.11 GO:0004435 ... P10688 9048554 MOAD: Kd=1.7uM
    3 1djx:B (2.3) BS03 I3P 3.1.4.11 GO:0004435 ... P10688 9048554 MOAD: Kd=1.7uM
    4 1gc6:A (2.9) BS01 I3P ? GO:0003779 ... P26043 10970839
    5 1h0a:A (1.7) BS01 I3P ? N/A O88339 12353027 MOAD: Kd=3.6uM
    PDBbind: -logKd/Ki=5.44, Kd=3.6uM
    6 1mai:A (1.9) BS01 I3P 3.1.4.11 GO:0035556 ... P10688 8521504 MOAD: Kd=210nM
    PDBbind: -logKd/Ki=6.68, Kd=210nM
    7 1n4k:A (2.2) BS01 I3P ? GO:0005220 ... P11881 12442173 MOAD: Kd=0.09nM
    PDBbind: -logKd/Ki=10.05, Kd=0.09nM
    8 1nu2:A (1.9) BS02 I3P ? N/A P97318 12737822
    9 1oqn:A (2.3) BS02 I3P ? N/A P97318 12826668
    10 1oqn:B (2.3) BS02 I3P ? N/A P97318 12826668
    11 1u29:A (1.8) BS01 I3P ? N/A P63034 15359279
    12 1w2c:A (1.95) BS02 I3P 2.7.1.127 GO:0016301 ... P23677 15350214
    13 1w2c:B (1.95) BS02 I3P 2.7.1.127 GO:0016301 ... P23677 15350214
    14 2a98:A (2.6) BS01 I3P 2.7.1.127 GO:0016301 ... Q96DU7 N/A
    15 2p0d:A (1.811) BS01 I3P ? N/A Q9BRR9 17339315 PDBbind: -logKd/Ki=7.00, Kd=0.1uM
    16 3c5n:A (1.8) BS01 I3P ? N/A O00294 N/A
    17 3c5n:B (1.8) BS01 I3P ? N/A O00294 N/A
    18 3c5n:B (1.8) BS02 I3P ? N/A O00294 N/A
    19 3t8s:B (3.77) BS01 I3P ? GO:0005220 ... P29994 21892169 PDBbind: -logKd/Ki=8.55, Kd=2.82nM
    BindingDB: Kd=8.7nM, EC50=209nM
    20 3uj0:A (3.6) BS01 I3P ? GO:0005220 ... P29994 22286060 BindingDB: Kd=8.7nM, EC50=209nM
    21 3uj0:B (3.6) BS01 I3P ? GO:0005220 ... P29994 22286060 BindingDB: Kd=8.7nM, EC50=209nM
    22 3v0h:A (1.85) BS01 I3P ? GO:0016311 ... Q4W8A1 22562138
    23 3v0h:A (1.85) BS02 I3P ? GO:0016311 ... Q4W8A1 22562138
    24 3v0h:B (1.85) BS01 I3P ? GO:0016311 ... Q4W8A1 22562138
    25 3v0h:B (1.85) BS02 I3P ? GO:0016311 ... Q4W8A1 22562138
    26 3w9f:A (1.9) BS01 I3P ? GO:0005216 ... A0A1D5PXA5 25256292
    27 3w9f:B (1.9) BS01 I3P ? GO:0005216 ... A0A1D5PXA5 25256292
    28 3w9f:C (1.9) BS01 I3P ? GO:0005216 ... A0A1D5PXA5 25256292
    29 3w9f:D (1.9) BS01 I3P ? GO:0005216 ... A0A1D5PXA5 25256292
    30 4np9:A (1.92) BS01 I3P ? GO:0016020 ... P47709 24302762 PDBbind: -logKd/Ki=5.03, Kd=9.4uM
    31 4o4d:A (2.1) BS01 I3P 2.7.-.- GO:0000828 ... N9UNA8 24956979
    32 4qj4:B (3.3) BS02 I3P 3.1.4.11 GO:0004435 ... Q01970 25435326
    33 4qj5:B (3.41) BS02 I3P 3.1.4.11 GO:0004435 ... Q01970 25435326
    34 4wu2:A (2.15) BS01 I3P 3.1.3.8 GO:0016787 ... Q7WUJ1 N/A
    35 4wu2:B (2.15) BS01 I3P 3.1.3.8 GO:0016787 ... Q7WUJ1 N/A
    36 5gug:A (7.399) BS01 I3P ? GO:0005220 ... P11881 28416699
    37 5gug:B (7.399) BS01 I3P ? GO:0005220 ... P11881 28416699
    38 5hjq:A (2.3) BS01 I3P ? N/A Q9VIH7 27669036 MOAD: Kd=19uM
    PDBbind: -logKd/Ki=4.72, Kd=19uM
    39 5j67:A (3.16) BS02 I3P ? GO:0001764 ... O75129 27249642
    40 5j67:C (3.16) BS02 I3P ? GO:0001764 ... O75129 27249642
    41 5w2h:A (1.9) BS02 I3P 2.7.1.140
    2.7.1.151
    2.7.1.153    		 GO:0016301 ... Q8NFU5 28882892
    42 5w2i:A (1.6) BS02 I3P 2.7.1.140
    2.7.1.151
    2.7.1.153    		 GO:0016301 ... Q8NFU5 28882892
    43 5x1o:A (1.9) BS01 I3P ? GO:0008083 ... P09038 N/A
    44 5x1o:A (1.9) BS02 I3P ? GO:0008083 ... P09038 N/A
    45 5xa1:A (6.204) BS01 I3P ? GO:0005220 ... P11881 28416699
    46 5xa1:B (6.204) BS01 I3P ? GO:0005220 ... P11881 28416699
    47 6cv8:A (-1.00) BS01 I3P 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.26.4
    3.4.23.-    		 N/A P03354 30309983 PDBbind: -logKd/Ki=3.17, Kd=0.68mM
    48 6dqn:A (3.33) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    49 6dqn:B (3.33) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    50 6dqn:C (3.33) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    51 6dqn:D (3.33) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    52 6dqs:A (4.12) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    53 6dqs:B (4.12) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    54 6dqs:C (4.12) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    55 6dqs:D (4.12) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    56 6dqv:A (3.82) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    57 6dqv:B (3.82) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    58 6dqv:C (3.82) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    59 6dqv:D (3.82) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    60 6dqz:A (6.01) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    61 6dqz:B (6.01) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    62 6dqz:C (6.01) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    63 6dqz:D (6.01) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    64 6dr0:A (4.47) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    65 6dr0:B (4.47) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    66 6dr0:C (4.47) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    67 6dr0:D (4.47) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    68 6drc:A (3.92) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    69 6drc:B (3.92) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    70 6drc:C (3.92) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    71 6drc:D (3.92) BS02 I3P ? GO:0000822 ... Q14573 30013099 BindingDB: Kd=195nM
    72 7f1x:A (3.0) BS01 I3P ? GO:0001664 ... P08168 34678158
    73 7f1x:B (3.0) BS01 I3P ? GO:0001664 ... P08168 34678158
    74 7f1x:C (3.0) BS01 I3P ? GO:0001664 ... P08168 34678158
    75 7f1x:D (3.0) BS01 I3P ? GO:0001664 ... P08168 34678158
    76 7jxa:A (2.4) BS01 I3P ? GO:0001664 ... P08168 34678158
    77 7jxa:B (2.4) BS01 I3P ? GO:0001664 ... P08168 34678158
    78 7jxa:C (2.4) BS01 I3P ? GO:0001664 ... P08168 34678158
    79 7jxa:D (2.4) BS01 I3P ? GO:0001664 ... P08168 34678158
    80 7t3p:A (3.2) BS02 I3P ? GO:0000822 ... Q14573 35301323
    81 7t3p:B (3.2) BS02 I3P ? GO:0000822 ... Q14573 35301323
    82 7t3p:C (3.2) BS02 I3P ? GO:0000822 ... Q14573 35301323
    83 7t3p:D (3.2) BS02 I3P ? GO:0000822 ... Q14573 35301323
    84 7t3q:A (3.3) BS02 I3P ? GO:0000822 ... Q14573 35301323
    85 7t3q:B (3.3) BS02 I3P ? GO:0000822 ... Q14573 35301323
    86 7t3q:C (3.3) BS02 I3P ? GO:0000822 ... Q14573 35301323
    87 7t3q:D (3.3) BS02 I3P ? GO:0000822 ... Q14573 35301323
    88 7t3r:A (3.4) BS02 I3P ? GO:0000822 ... Q14573 35301323
    89 7t3r:B (3.4) BS02 I3P ? GO:0000822 ... Q14573 35301323
    90 7t3r:C (3.4) BS02 I3P ? GO:0000822 ... Q14573 35301323
    91 7t3r:D (3.4) BS02 I3P ? GO:0000822 ... Q14573 35301323
    92 7t3t:A (3.8) BS02 I3P ? GO:0000822 ... Q14573 35301323
    93 7t3t:B (3.8) BS02 I3P ? GO:0000822 ... Q14573 35301323
    94 7t3t:C (3.8) BS02 I3P ? GO:0000822 ... Q14573 35301323
    95 7t3t:D (3.8) BS02 I3P ? GO:0000822 ... Q14573 35301323
    96 7t3u:D (3.7) BS02 I3P ? GO:0000822 ... Q14573 35301323
    97 7z3j:A (2.0) BS03 I3P 3.1.4.11 GO:0004435 ... P10686 35749497
    98 8ear:A (3.5) BS03 I3P ? GO:0000902 ... P29994 36376291
    99 8ear:B (3.5) BS04 I3P ? GO:0000902 ... P29994 36376291
    100 8ear:C (3.5) BS07 I3P ? GO:0000902 ... P29994 36376291
    101 8ear:D (3.5) BS05 I3P ? GO:0000902 ... P29994 36376291
    102 8qbb:A (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    103 8qbb:B (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    104 8qbb:C (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    105 8qbb:D (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    106 8qbb:E (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    107 8qbb:F (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    108 8qbb:G (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    109 8qbb:H (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    110 8qbb:I (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    111 8qbb:J (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    112 8qbb:K (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    113 8qbb:L (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    114 8qbb:M (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    115 8qbb:N (3.86) BS01 I3P N/A GO:0005515 ... P53252 39048819
    116 8qbd:A (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    117 8qbd:B (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    118 8qbd:C (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    119 8qbd:D (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    120 8qbd:E (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    121 8qbd:F (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    122 8qbd:G (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    123 8qbd:H (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    124 8qbd:I (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    125 8qbd:J (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    126 8qbd:K (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    127 8qbd:L (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    128 8qbd:M (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    129 8qbd:N (3.61) BS01 I3P N/A GO:0005515 ... P53252 39048819
    130 8qbf:A (3.67) BS01 I3P N/A N/A P53252 39048819
    131 8qbf:B (3.67) BS01 I3P N/A N/A P53252 39048819
    132 8t8y:A (2.5) BS02 I3P ? GO:0000828 ... A0A3G4ZNY6 38216735
    133 8tk8:A (2.7) BS02 I3P ? GO:0000822 ... Q14573 37898605
    134 8tk8:B (2.7) BS02 I3P ? GO:0000822 ... Q14573 37898605
    135 8tk8:C (2.7) BS02 I3P ? GO:0000822 ... Q14573 37898605
    136 8tk8:D (2.7) BS02 I3P ? GO:0000822 ... Q14573 37898605
    137 8tkd:A (3.7) BS02 I3P ? GO:0000822 ... Q14573 37898605
    138 8tkd:B (3.7) BS02 I3P ? GO:0000822 ... Q14573 37898605
    139 8tkd:C (3.7) BS02 I3P ? GO:0000822 ... Q14573 37898605
    140 8tkd:D (3.7) BS02 I3P ? GO:0000822 ... Q14573 37898605
    141 8tke:A (3.6) BS02 I3P ? GO:0000822 ... Q14573 37898605
    142 8tke:B (3.6) BS02 I3P ? GO:0000822 ... Q14573 37898605
    143 8tke:C (3.6) BS02 I3P ? GO:0000822 ... Q14573 37898605
    144 8tke:D (3.6) BS02 I3P ? GO:0000822 ... Q14573 37898605
    145 8tkf:A (3.2) BS02 I3P ? GO:0000822 ... Q14573 37898605
    146 8tkf:B (3.2) BS03 I3P ? GO:0000822 ... Q14573 37898605
    147 8tkf:C (3.2) BS03 I3P ? GO:0000822 ... Q14573 37898605
    148 8tkf:D (3.2) BS04 I3P ? GO:0000822 ... Q14573 37898605
    149 8tkg:A (2.5) BS02 I3P ? GO:0000822 ... Q14573 37898605
    150 8tkg:B (2.5) BS02 I3P ? GO:0000822 ... Q14573 37898605
    151 8tkg:C (2.5) BS02 I3P ? GO:0000822 ... Q14573 37898605
    152 8tkg:D (2.5) BS02 I3P ? GO:0000822 ... Q14573 37898605
    153 8tkh:A (3.5) BS02 I3P ? GO:0000822 ... Q14573 37898605
    154 8tkh:B (3.5) BS02 I3P ? GO:0000822 ... Q14573 37898605
    155 8tkh:C (3.5) BS02 I3P ? GO:0000822 ... Q14573 37898605
    156 8tkh:D (3.5) BS02 I3P ? GO:0000822 ... Q14573 37898605
    157 8tki:A (3.6) BS02 I3P ? GO:0000822 ... Q14573 37898605
    158 8tki:B (3.6) BS02 I3P ? GO:0000822 ... Q14573 37898605
    159 8tki:C (3.6) BS02 I3P ? GO:0000822 ... Q14573 37898605
    160 8tki:D (3.6) BS02 I3P ? GO:0000822 ... Q14573 37898605
    161 8tl9:A (3.3) BS02 I3P ? GO:0000822 ... Q14573 37898605
    162 8tl9:B (3.3) BS02 I3P ? GO:0000822 ... Q14573 37898605
    163 8tl9:C (3.3) BS02 I3P ? GO:0000822 ... Q14573 37898605
    164 8tl9:D (3.3) BS02 I3P ? GO:0000822 ... Q14573 37898605
    165 8tla:A (3.2) BS02 I3P ? GO:0000822 ... Q14573 37898605
    166 8tla:B (3.2) BS02 I3P ? GO:0000822 ... Q14573 37898605
    167 8tla:C (3.2) BS02 I3P ? GO:0000822 ... Q14573 37898605
    168 8tla:D (3.2) BS02 I3P ? GO:0000822 ... Q14573 37898605
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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