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BioLiP
Download all results in tab-seperated text for 83 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1avn:A (2.0) BS03 HSM 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 9265618 MOAD: Kd=0.125mM
    PDBbind: -logKd/Ki=3.90, Kd=0.125mM
    2 1ike:A (1.5) BS02 HSM 1.7.6.1 GO:0005576 ... Q94734 11560480
    3 1jqd:A (2.28) BS02 HSM 2.1.1.8 GO:0001692 ... P50135 11566133
    4 1jqd:B (2.28) BS02 HSM 2.1.1.8 GO:0001692 ... P50135 11566133
    5 1kar:A (2.1) BS02 HSM 1.1.1.23 GO:0000105 ... P06988 11842181
    6 1kar:B (2.1) BS01 HSM 1.1.1.23 GO:0000105 ... P06988 11842181
    7 1kar:B (2.1) BS03 HSM 1.1.1.23 GO:0000105 ... P06988 11842181
    8 1np1:A (2.0) BS02 HSM ? GO:0005576 ... Q26239 9546222
    9 1np1:B (2.0) BS02 HSM ? GO:0005576 ... Q26239 9546222
    10 1qft:A (1.25) BS01 HSM ? GO:0005576 ... O77421 10360182 MOAD: Kd=1.7nM
    PDBbind: -logKd/Ki=8.77, Kd=1.7nM
    11 1qft:A (1.25) BS02 HSM ? GO:0005576 ... O77421 10360182 MOAD: Kd=1.7nM
    PDBbind: -logKd/Ki=8.77, Kd=1.7nM
    12 1qft:B (1.25) BS01 HSM ? GO:0005576 ... O77421 10360182 MOAD: Kd=1.7nM
    13 1qft:B (1.25) BS02 HSM ? GO:0005576 ... O77421 10360182 MOAD: Kd=1.7nM
    14 1qft:B (1.25) BS03 HSM ? GO:0005576 ... O77421 10360182 MOAD: Kd=1.7nM
    15 1qfv:A (1.36) BS01 HSM ? GO:0005576 ... O77421 10360182
    16 1qfv:B (1.36) BS01 HSM ? GO:0005576 ... O77421 10360182
    17 1qfv:B (1.36) BS02 HSM ? GO:0005576 ... O77421 10360182
    18 1u18:A (1.96) BS02 HSM ? GO:0005576 ... Q26239 N/A
    19 1u18:B (1.96) BS02 HSM ? GO:0005576 ... Q26239 N/A
    20 2qeb:A (2.003) BS01 HSM ? GO:0005549 ... Q7PNF2 17928288
    21 2qeb:B (2.003) BS01 HSM ? GO:0005549 ... Q7PNF2 17928288
    22 2x45:A (1.4) BS01 HSM ? GO:0005576 ... Q5GQ85 N/A
    23 2x45:A (1.4) BS02 HSM ? GO:0005576 ... Q5GQ85 N/A
    24 2x45:A (1.4) BS03 HSM ? GO:0005576 ... Q5GQ85 N/A
    25 2x45:B (1.4) BS01 HSM ? GO:0005576 ... Q5GQ85 N/A
    26 2x45:B (1.4) BS02 HSM ? GO:0005576 ... Q5GQ85 N/A
    27 2x45:B (1.4) BS03 HSM ? GO:0005576 ... Q5GQ85 N/A
    28 2x45:C (1.4) BS01 HSM ? GO:0005576 ... Q5GQ85 N/A
    29 2x45:C (1.4) BS02 HSM ? GO:0005576 ... Q5GQ85 N/A
    30 2x45:C (1.4) BS03 HSM ? GO:0005576 ... Q5GQ85 N/A
    31 3bu1:A (1.4) BS01 HSM ? GO:0030682 ... Q09JX9 18445596 MOAD: Kd=7.1nM
    PDBbind: -logKd/Ki=8.15, Kd=7.1nM
    32 3g7x:A (1.55) BS01 HSM ? GO:0005576 ... O77421 N/A
    33 3g7x:B (1.55) BS01 HSM ? GO:0005576 ... O77421 N/A
    34 3rxh:A (1.7) BS02 HSM 3.4.21.4 GO:0004175 ... P00760 N/A PDBbind: -logKd/Ki=1.80, IC50=15.7mM
    35 4xmf:A (1.6) BS02 HSM 1.7.6.1 GO:0005576 ... Q6PQK2 26167269
    36 5rus:A (1.0) BS01 HSM 2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-    		 N/A P0DTD1 33853786
    37 6dyn:A (2.102) BS01 HSM 6.3.2.- N/A Q9VDC6 30705105 MOAD: Kd=638.9uM
    PDBbind: -logKd/Ki=3.19, Kd=638.9uM
    38 6fu4:A (2.45) BS01 HSM ? N/A Q9I0I4 30425146 MOAD: Kd=639nM
    PDBbind: -logKd/Ki=6.19, Kd=639nM
    39 6fu4:B (2.45) BS01 HSM ? N/A Q9I0I4 30425146 MOAD: Kd=639nM
    40 6fu4:C (2.45) BS01 HSM ? N/A Q9I0I4 30425146 MOAD: Kd=639nM
    41 6fu4:D (2.45) BS01 HSM ? N/A Q9I0I4 30425146 MOAD: Kd=639nM
    42 6qfa:A (2.49) BS01 HSM ? GO:0004888 ... P28472 33408403
    43 6qfa:A (2.49) BS02 HSM ? GO:0004888 ... P28472 33408403
    44 6qfa:B (2.49) BS01 HSM ? GO:0004888 ... P28472 33408403
    45 6qfa:B (2.49) BS02 HSM ? GO:0004888 ... P28472 33408403
    46 6qfa:C (2.49) BS01 HSM ? GO:0004888 ... P28472 33408403
    47 6qfa:C (2.49) BS02 HSM ? GO:0004888 ... P28472 33408403
    48 6qfa:D (2.49) BS01 HSM ? GO:0004888 ... P28472 33408403
    49 6qfa:D (2.49) BS02 HSM ? GO:0004888 ... P28472 33408403
    50 6qfa:E (2.49) BS01 HSM ? GO:0004888 ... P28472 33408403
    51 6qfa:E (2.49) BS02 HSM ? GO:0004888 ... P28472 33408403
    52 7a5v:A (1.7) BS01 HSM ? GO:0004888 ... P28472 33087931
    53 7dfl:R (3.3) BS01 HSM ? GO:0004930 ... P35367 33828102 BindingDB: EC50=190nM, Ki=6000nM
    54 7pbz:C (2.79) BS01 HSM ? GO:0004888 ... P28472 35140402
    55 7pc0:C (3.0) BS01 HSM ? GO:0004888 ... P28472 35140402
    56 7qn7:B (3.0) BS02 HSM ? GO:0004888 ... P28472 35355020
    57 7qn7:C (3.0) BS01 HSM ? GO:0004888 ... P28472 35355020
    58 7qn7:D (3.0) BS01 HSM ? GO:0004888 ... P28472 35355020
    59 7qn8:A (3.1) BS01 HSM ? GO:0004888 ... P28472 35355020
    60 7qn8:B (3.1) BS01 HSM ? GO:0004888 ... P28472 35355020
    61 7qn8:B (3.1) BS02 HSM ? GO:0004888 ... P28472 35355020
    62 7qn8:C (3.1) BS01 HSM ? GO:0004888 ... P28472 35355020
    63 7qn8:C (3.1) BS02 HSM ? GO:0004888 ... P28472 35355020
    64 7qn8:D (3.1) BS01 HSM ? GO:0004888 ... P28472 35355020
    65 7qn9:A (2.9) BS01 HSM ? GO:0004888 ... P48169 35355020
    66 7qn9:B (2.9) BS01 HSM ? GO:0004888 ... P28472 35355020
    67 7qn9:C (2.9) BS01 HSM ? GO:0004888 ... P28472 35355020
    68 7qn9:D (2.9) BS01 HSM ? GO:0004888 ... P28472 35355020
    69 7qnc:C (2.9) BS01 HSM ? GO:0004888 ... P28472 35355020
    70 7qnc:D (2.9) BS01 HSM ? GO:0004888 ... P28472 35355020
    71 7qnd:A (3.4) BS01 HSM ? GO:0004888 ... P28472 35355020
    72 7qnd:B (3.4) BS01 HSM ? GO:0004888 ... P28472 35355020
    73 7qnd:B (3.4) BS02 HSM ? GO:0004888 ... P28472 35355020
    74 7qnd:C (3.4) BS01 HSM ? GO:0004888 ... P28472 35355020
    75 7qnd:C (3.4) BS02 HSM ? GO:0004888 ... P28472 35355020
    76 7yfc:R (3.0) BS01 HSM ? GO:0004930 ... Q9H3N8 37863901
    77 8hn8:R (3.0) BS01 HSM ? GO:0004930 ... P0ABE7
    Q9H3N8    		 N/A
    78 8jt5:A (3.06) BS01 HSM ? GO:0016020 ... Q05940 N/A
    79 8jxt:R (3.07) BS01 HSM ? GO:0004930 ... Q9H3N8 38509098
    80 8pok:A (3.4) BS01 HSM ? GO:0001696 ... P25021 38418462
    81 8pvb:A (3.6) BS01 HSM ? GO:0004888 ... P28472 38011573
    82 8tgk:A (3.7) BS01 HSM ? GO:0005335 ... P54219 38499039
    83 8yuu:R (2.7) BS01 HSM ? GO:0004930 ... Q9Y5N1 38647423
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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