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BioLiP
Download all results in tab-seperated text for 6 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1c5n:H (1.5) BS03 ESI 3.4.21.5 GO:0004252 ... P00734 10779411 MOAD: Ki=20uM
    PDBbind: -logKd/Ki=4.70, Ki=20uM
    BindingDB: Ki=20000nM
    2 1c5q:A (1.43) BS02 ESI 3.4.21.4 GO:0004175 ... P00760 10779411 MOAD: Ki=0.44uM
    PDBbind: -logKd/Ki=6.36, Ki=0.44uM
    BindingDB: Ki=440nM
    3 1c5r:A (1.47) BS02 ESI 3.4.21.4 GO:0004175 ... P00760 10779411 BindingDB: Ki=440nM
    4 1c5w:B (1.94) BS02 ESI 3.4.21.73 GO:0004252 ... P00749 10779411 BindingDB: Ki=210nM
    5 1c5x:B (1.75) BS02 ESI 3.4.21.73 GO:0004252 ... P00749 10779411 MOAD: Ki=0.21uM
    PDBbind: -logKd/Ki=6.68, Ki=0.21uM
    BindingDB: Ki=210nM
    6 1o5b:B (1.85) BS02 ESI 3.4.21.73 GO:0004252 ... P00749 15522303 MOAD: Ki=1.7uM
    PDBbind: -logKd/Ki=5.77, Ki=1.7uM
    BindingDB: Ki=210nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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