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BioLiP
Download all results in tab-seperated text for 109 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1e3v:A (2.0) BS01 DXC 5.3.3.1 GO:0004769 ... P07445 11007792 MOAD: Kd=45.74uM
    PDBbind: -logKd/Ki=4.34, Kd=45.74uM
    2 1e3v:B (2.0) BS01 DXC 5.3.3.1 GO:0004769 ... P07445 11007792 MOAD: Kd=45.74uM
    3 1fm4:A (1.97) BS01 DXC ? GO:0004864 ... P43185 12473456
    4 1fm4:A (1.97) BS02 DXC ? GO:0004864 ... P43185 12473456
    5 1os6:A (1.45) BS04 DXC ? GO:0009055 ... Q8GGK7 14744127
    6 2bjf:A (1.67) BS01 DXC 2.3.1.-
    3.5.1.-
    3.5.1.24    		 GO:0006629 ... P54965 15823032
    7 2opx:A (2.53) BS01 DXC 1.2.1.21
    1.2.1.22    		 GO:0004777 ... P25553 N/A
    8 2opx:A (2.53) BS02 DXC 1.2.1.21
    1.2.1.22    		 GO:0004777 ... P25553 N/A
    9 2opx:A (2.53) BS03 DXC 1.2.1.21
    1.2.1.22    		 GO:0004777 ... P25553 N/A
    10 2w1b:A (3.85) BS01 DXC ? GO:0005515 ... P31224 19023693
    11 3dtu:C (2.15) BS08 DXC 7.1.1.9 GO:0004129 ... P33517 18759498
    12 3dtu:D (2.15) BS02 DXC 7.1.1.9 GO:0004129 ... Q03736 18759498
    13 3o01:A (1.9) BS01 DXC ? N/A Q56026 21031487
    14 3o01:B (1.9) BS01 DXC ? N/A Q56026 21031487
    15 3r9v:B (1.9) BS01 DXC ? N/A P18013 22423359
    16 3r9v:B (1.9) BS02 DXC ? N/A P18013 22423359
    17 3rv5:A (2.2) BS01 DXC ? GO:0005509 ... P63316 21920370
    18 3rv5:A (2.2) BS02 DXC ? GO:0005509 ... P63316 21920370
    19 3rv5:A (2.2) BS03 DXC ? GO:0005509 ... P63316 21920370
    20 3rv5:C (2.2) BS01 DXC ? GO:0005509 ... P63316 21920370
    21 3rv5:D (2.2) BS01 DXC ? GO:0005509 ... P63316 21920370
    22 3sel:X (2.1) BS04 DXC ? GO:0009055 ... Q8GGK7 23099666
    23 3sj0:X (2.0) BS04 DXC ? GO:0009055 ... Q8GGK7 23099666
    24 3sj1:X (1.9) BS04 DXC ? GO:0009055 ... Q8GGK7 23099666
    25 3sj4:X (1.9) BS04 DXC ? GO:0009055 ... Q8GGK7 23099666
    26 3zqe:A (2.19) BS01 DXC ? GO:0005576 ... P41784
    Q56026    		 21829362
    27 3zqe:B (2.19) BS01 DXC ? GO:0005576 ... P41784
    Q56026    		 21829362 MOAD: Kd=59uM
    PDBbind: -logKd/Ki=4.23, Kd=59.0uM
    28 4a81:A (2.05) BS01 DXC ? GO:0004864 ... P15494 22634284
    29 4a83:A (1.54) BS01 DXC ? GO:0004864 ... P15494 22634284
    30 4a83:A (1.54) BS02 DXC ? GO:0004864 ... P15494 22634284
    31 4a84:A (1.5) BS01 DXC ? GO:0004864 ... P15494 22634284
    32 4a84:A (1.5) BS02 DXC ? GO:0004864 ... P15494 22634284
    33 4ac9:B (3.03) BS02 DXC ? GO:0001514 ... Q8J307 15616587
    34 4ac9:C (3.03) BS02 DXC ? GO:0001514 ... Q8J307 15616587
    35 4ac9:C (3.03) BS03 DXC ? GO:0001514 ... Q8J307 15616587
    36 4ac9:C (3.03) BS04 DXC ? GO:0001514 ... Q8J307 15616587
    37 4ac9:C (3.03) BS05 DXC ? GO:0001514 ... Q8J307 15616587
    38 4ac9:C (3.03) BS06 DXC ? GO:0001514 ... Q8J307 15616587
    39 4ac9:C (3.03) BS07 DXC ? GO:0001514 ... Q8J307 15616587
    40 4aca:B (3.15) BS01 DXC ? GO:0001514 ... Q8J307 15616587
    41 4aca:C (3.15) BS01 DXC ? GO:0001514 ... Q8J307 15616587
    42 4aca:C (3.15) BS02 DXC ? GO:0001514 ... Q8J307 15616587
    43 4aca:C (3.15) BS03 DXC ? GO:0001514 ... Q8J307 15616587
    44 4aca:C (3.15) BS04 DXC ? GO:0001514 ... Q8J307 15616587
    45 4aca:C (3.15) BS05 DXC ? GO:0001514 ... Q8J307 15616587
    46 4aca:C (3.15) BS06 DXC ? GO:0001514 ... Q8J307 15616587
    47 4acb:B (3.34) BS02 DXC ? GO:0001514 ... Q8J307 15616587
    48 4acb:C (3.34) BS01 DXC ? GO:0001514 ... Q8J307 15616587
    49 4acb:C (3.34) BS02 DXC ? GO:0001514 ... Q8J307 15616587
    50 4acb:C (3.34) BS03 DXC ? GO:0001514 ... Q8J307 15616587
    51 4acb:C (3.34) BS04 DXC ? GO:0001514 ... Q8J307 15616587
    52 4acb:C (3.34) BS05 DXC ? GO:0001514 ... Q8J307 15616587
    53 4acb:C (3.34) BS06 DXC ? GO:0001514 ... Q8J307 15616587
    54 4haj:A (1.9) BS04 DXC ? GO:0009055 ... Q8GGK7 N/A
    55 4hb6:A (1.9) BS04 DXC ? GO:0009055 ... Q8GGK7 N/A
    56 4hb8:A (1.9) BS04 DXC ? GO:0009055 ... Q8GGK7 N/A
    57 4hbf:A (1.9) BS04 DXC ? GO:0009055 ... Q8GGK7 N/A
    58 4hc3:A (1.95) BS04 DXC ? GO:0009055 ... Q8GGK7 N/A
    59 4hdl:A (1.9) BS04 DXC ? GO:0009055 ... Q8GGK7 N/A
    60 4qn9:A (2.652) BS03 DXC 3.1.4.54 GO:0000139 ... Q6IQ20 25684574 PDBbind: -logKd/Ki=4.41, Kd=38.5uM
    61 4qn9:A (2.652) BS04 DXC 3.1.4.54 GO:0000139 ... Q6IQ20 25684574 PDBbind: -logKd/Ki=4.41, Kd=38.5uM
    62 4qn9:A (2.652) BS05 DXC 3.1.4.54 GO:0000139 ... Q6IQ20 25684574 PDBbind: -logKd/Ki=4.41, Kd=38.5uM
    63 4qn9:B (2.652) BS01 DXC 3.1.4.54 GO:0000139 ... Q6IQ20 25684574 PDBbind: -logKd/Ki=4.41, Kd=38.5uM
    64 4qn9:B (2.652) BS02 DXC 3.1.4.54 GO:0000139 ... Q6IQ20 25684574 PDBbind: -logKd/Ki=4.41, Kd=38.5uM
    65 4qn9:B (2.652) BS03 DXC 3.1.4.54 GO:0000139 ... Q6IQ20 25684574 PDBbind: -logKd/Ki=4.41, Kd=38.5uM
    66 4qn9:B (2.652) BS06 DXC 3.1.4.54 GO:0000139 ... Q6IQ20 25684574 PDBbind: -logKd/Ki=4.41, Kd=38.5uM
    67 4qn9:B (2.652) BS07 DXC 3.1.4.54 GO:0000139 ... Q6IQ20 25684574 PDBbind: -logKd/Ki=4.41, Kd=38.5uM
    68 4zp0:A (2.0) BS01 DXC ? GO:0005886 ... P0AEY8 26238402
    69 6euq:A (2.2) BS01 DXC ? GO:0005886 ... P0AEY8 29530612
    70 6m5o:A (2.30001) BS01 DXC 2.1.2.1 GO:0002082 ... P34897 33521601
    71 6m5o:A (2.30001) BS02 DXC 2.1.2.1 GO:0002082 ... P34897 33521601
    72 6m5o:B (2.30001) BS01 DXC 2.1.2.1 GO:0002082 ... P34897 33521601
    73 6m5o:B (2.30001) BS02 DXC 2.1.2.1 GO:0002082 ... P34897 33521601
    74 6m5w:A (3.1) BS02 DXC 2.1.2.1 GO:0000900 ... P34896 33521601
    75 6ooq:A (3.0) BS01 DXC ? GO:0005886 ... P0AEY8 31240248
    76 6q2t:A (2.8) BS03 DXC 1.14.14.154 GO:0004497 ... Q16850 31663733
    77 6q2t:A (2.8) BS04 DXC 1.14.14.154 GO:0004497 ... Q16850 31663733
    78 6uad:A (1.75) BS01 DXC 5.3.3.1 GO:0004769 ... P00947 N/A
    79 6uad:A (1.75) BS02 DXC 5.3.3.1 GO:0004769 ... P00947 N/A
    80 6uae:A (1.93) BS01 DXC 5.3.3.1 GO:0004769 ... P00947 N/A
    81 6uae:C (1.93) BS01 DXC 5.3.3.1 GO:0004769 ... P00947 N/A
    82 6uae:D (1.93) BS01 DXC 5.3.3.1 GO:0004769 ... P00947 N/A
    83 6vs1:A (3.0) BS01 DXC ? GO:0005886 ... P0AEY8 32127561
    84 8p90:A (2.8) BS03 DXC N/A GO:0000139 ... Q6IQ20 N/A
    85 8p90:A (2.8) BS04 DXC N/A GO:0000139 ... Q6IQ20 N/A
    86 8p90:A (2.8) BS05 DXC N/A GO:0000139 ... Q6IQ20 N/A
    87 8p90:A (2.8) BS06 DXC N/A GO:0000139 ... Q6IQ20 N/A
    88 8p90:A (2.8) BS08 DXC N/A GO:0000139 ... Q6IQ20 N/A
    89 8p90:A (2.8) BS09 DXC N/A GO:0000139 ... Q6IQ20 N/A
    90 8p90:B (2.8) BS02 DXC N/A GO:0000139 ... Q6IQ20 N/A
    91 8p90:B (2.8) BS03 DXC N/A GO:0000139 ... Q6IQ20 N/A
    92 8p90:B (2.8) BS06 DXC N/A GO:0000139 ... Q6IQ20 N/A
    93 8p96:A (2.86) BS03 DXC N/A GO:0000139 ... Q6IQ20 N/A
    94 8p96:A (2.86) BS04 DXC N/A GO:0000139 ... Q6IQ20 N/A
    95 8p96:A (2.86) BS05 DXC N/A GO:0000139 ... Q6IQ20 N/A
    96 8p96:A (2.86) BS06 DXC N/A GO:0000139 ... Q6IQ20 N/A
    97 8p96:B (2.86) BS01 DXC N/A GO:0000139 ... Q6IQ20 N/A
    98 8p96:B (2.86) BS02 DXC N/A GO:0000139 ... Q6IQ20 N/A
    99 8p96:B (2.86) BS05 DXC N/A GO:0000139 ... Q6IQ20 N/A
    100 8pc4:A (2.85) BS03 DXC N/A GO:0000139 ... Q6IQ20 N/A
    101 8pc4:A (2.85) BS04 DXC N/A GO:0000139 ... Q6IQ20 N/A
    102 8pc4:A (2.85) BS05 DXC N/A GO:0000139 ... Q6IQ20 N/A
    103 8pc4:A (2.85) BS06 DXC N/A GO:0000139 ... Q6IQ20 N/A
    104 8pc4:B (2.85) BS01 DXC N/A GO:0000139 ... Q6IQ20 N/A
    105 8pc4:B (2.85) BS02 DXC N/A GO:0000139 ... Q6IQ20 N/A
    106 8pc4:B (2.85) BS03 DXC N/A GO:0000139 ... Q6IQ20 N/A
    107 8v5c:B (1.96) BS01 DXC N/A N/A P18013 39079629
    108 8v5c:B (1.96) BS02 DXC N/A N/A P18013 39079629
    109 8v5e:A (2.2) BS01 DXC N/A N/A P18013 39079629
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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