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BioLiP
Download all results in tab-seperated text for 11 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1acl:A (2.8) BS01 DME 3.1.1.7 GO:0001507 ... P04058 8415649
    2 1maa:A (2.9) BS01 DME 3.1.1.7 GO:0001919 ... P21836 9915834 BindingDB: Ki=460nM
    3 1maa:B (2.9) BS01 DME 3.1.1.7 GO:0001919 ... P21836 9915834 BindingDB: Ki=460nM
    4 1maa:C (2.9) BS01 DME 3.1.1.7 GO:0001919 ... P21836 9915834 BindingDB: Ki=460nM
    5 1maa:D (2.9) BS01 DME 3.1.1.7 GO:0001919 ... P21836 9915834 BindingDB: Ki=460nM
    6 2xud:A (2.65) BS01 DME 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=460nM
    7 3mes:A (2.35) BS02 DME ? GO:0000166 ... Q5CUP2 N/A
    8 3mes:B (2.35) BS02 DME ? GO:0000166 ... Q5CUP2 N/A
    9 5e2i:A (2.65) BS01 DME 3.1.1.7 GO:0001507 ... P04058 26990888
    10 5e4j:A (2.54) BS01 DME 3.1.1.7 GO:0001507 ... P04058 26990888
    11 6ep4:A (2.30005) BS02 DME 3.1.1.8 GO:0001540 ... P06276 29186056 MOAD: Ki=4.5uM
    PDBbind: -logKd/Ki=5.35, Ki=4.5uM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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