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BioLiP
Download all results in tab-seperated text for 18 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1i1e:A (2.5) BS01 DM2 3.4.24.69 GO:0004222 ... P10844 11679763 MOAD: Kd=9.4uM
    PDBbind: -logKd/Ki=5.03, Kd=9.4uM
    2 2dr6:A (3.3) BS01 DM2 ? GO:0005515 ... P31224 16915237
    3 4dx7:A (2.253) BS01 DM2 ? GO:0005515 ... P31224 22451937
    4 4dx7:A (2.253) BS02 DM2 ? GO:0005515 ... P31224 22451937
    5 4dx7:B (2.253) BS01 DM2 ? GO:0005515 ... P31224 22451937
    6 4zvm:A (1.973) BS03 DM2 1.10.5.1 GO:0001512 ... P16083 26636353 MOAD: Kd=274nM
    7 4zvm:A (1.973) BS04 DM2 1.10.5.1 GO:0001512 ... P16083 26636353 MOAD: Kd=274nM
    8 4zvm:B (1.973) BS01 DM2 1.10.5.1 GO:0001512 ... P16083 26636353 MOAD: Kd=274nM
    9 4zvm:B (1.973) BS04 DM2 1.10.5.1 GO:0001512 ... P16083 26636353 MOAD: Kd=274nM
    10 5mra:B (3.74) BS02 DM2 ? GO:0005509 ... P30626 28726784 PDBbind: -logKd/Ki=8.00, Kd=10nM
    11 5om7:A (1.727) BS01 DM2 ? GO:0003677 ... P01011 29760101 PDBbind: -logKd/Ki=5.74, Kd=1.8uM
    12 5om7:B (1.727) BS01 DM2 ? N/A P01011 29760101 PDBbind: -logKd/Ki=5.74, Kd=1.8uM
    13 6ftp:A (1.8) BS01 DM2 ? GO:0003677 ... P01011 29760101 PDBbind: -logKd/Ki=5.82, Kd=1.5uM
    14 6ftp:B (1.8) BS01 DM2 ? N/A P01011 29760101 PDBbind: -logKd/Ki=5.82, Kd=1.5uM
    15 8r2j:A (2.4) BS01 DM2 N/A N/A N/A N/A
    16 8r2j:A (2.4) BS02 DM2 N/A N/A N/A N/A
    17 8r2j:B (2.4) BS01 DM2 N/A N/A N/A N/A
    18 8r2j:B (2.4) BS02 DM2 N/A N/A N/A N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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