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BioLiP
Download all results in tab-seperated text for 32 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1m2z:A (2.5) BS02 DEX ? N/A P04150 12151000 BindingDB: EC50=2.5nM, Ki=1.2nM, IC50=5nM, Kd=19nM
    2 1m2z:D (2.5) BS02 DEX ? N/A P04150 12151000 BindingDB: EC50=2.5nM, Ki=1.2nM, IC50=5nM, Kd=19nM
    3 1p93:A (2.7) BS03 DEX ? N/A P04150 12686538 PDBbind: -logKd/Ki=7.72, Kd=19nM
    BindingDB: EC50=2.5nM, Ki=1.2nM, IC50=5nM, Kd=19nM
    4 1p93:B (2.7) BS02 DEX ? N/A P04150 12686538 BindingDB: EC50=2.5nM, Ki=1.2nM, IC50=5nM, Kd=19nM
    5 1p93:C (2.7) BS03 DEX ? N/A P04150 12686538 BindingDB: EC50=2.5nM, Ki=1.2nM, IC50=5nM, Kd=19nM
    6 1p93:D (2.7) BS02 DEX ? N/A P04150 12686538 BindingDB: EC50=2.5nM, Ki=1.2nM, IC50=5nM, Kd=19nM
    7 3gn8:A (2.5) BS02 DEX N/A N/A N/A 19779450
    8 3gn8:B (2.5) BS02 DEX N/A N/A N/A 19779450
    9 3mne:A (1.96) BS02 DEX ? N/A P06537 20850457
    10 3mno:A (1.55) BS02 DEX ? N/A P06537 20850457
    11 3mnp:A (1.5) BS02 DEX ? N/A P06537 20850457
    12 4uda:A (2.03) BS02 DEX ? N/A P08235 26602186 MOAD: Ki=6.3nM
    PDBbind: -logKd/Ki=7.59, IC50=26.0nM
    BindingDB: IC50=33nM, Ki=7.2nM
    13 4udc:A (2.5) BS02 DEX ? N/A P04150 26602186 BindingDB: EC50=2.5nM, Ki=1.2nM, IC50=5nM, Kd=19nM
    14 6nwk:A (1.65) BS02 DEX N/A N/A N/A 31391291 MOAD: Ki=20nM
    PDBbind: -logKd/Ki=7.70, Ki=20nM
    15 6xk0:A (2.4) BS01 DEX ? GO:0003677 ... P35747 33063792
    16 7krj:D (2.56) BS01 DEX ? N/A P04150 34937936 BindingDB: EC50=2.5nM, Ki=1.2nM, IC50=5nM, Kd=19nM
    17 7yxc:A (2.25) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    18 7yxd:A (2.3) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    19 7yxd:D (2.3) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    20 7yxd:H (2.3) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    21 7yxd:L (2.3) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    22 7yxn:A (2.46) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    23 7yxn:C (2.46) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    24 7yxo:A (2.99) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    25 7yxo:C (2.99) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    26 7yxo:E (2.99) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    27 7yxp:A (3.36) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    28 7yxp:A (3.36) BS03 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    29 7yxr:A (2.5) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    30 7yxr:C (2.5) BS02 DEX ? GO:0003677 ... A0A1X8XLE9 36464162
    31 8ffv:C (3.01) BS01 DEX ? GO:0003700 ... P04150 37945740
    32 8ffw:C (3.23) BS01 DEX ? GO:0003700 ... P04150 37945740
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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