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BioLiP
Download all results in tab-seperated text for 10 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1uwh:A (2.95) BS01 BAX 2.7.11.1 GO:0004672 ... P15056 15035987 PDBbind: -logKd/Ki=7.66, IC50=22nM
    BindingDB: IC50=22nM, Kd=260nM, Ki=22nM
    2 1uwh:B (2.95) BS01 BAX 2.7.11.1 GO:0004672 ... P15056 15035987 BindingDB: IC50=22nM, Kd=260nM, Ki=22nM
    3 1uwj:A (3.5) BS01 BAX 2.7.11.1 GO:0004672 ... P15056 15035987 BindingDB: IC50=22nM, Kd=260nM, Ki=22nM
    4 1uwj:B (3.5) BS01 BAX 2.7.11.1 GO:0004672 ... P15056 15035987 BindingDB: IC50=22nM, Kd=260nM, Ki=22nM
    5 3gcs:A (2.1) BS01 BAX 2.7.11.24 GO:0000077 ... Q16539 19572644 MOAD: Kd=56nM
    PDBbind: -logKd/Ki=7.25, Kd=56nM
    BindingDB: Kd=370nM, IC50=400nM
    6 3heg:A (2.2) BS01 BAX 2.7.11.24 GO:0000077 ... Q16539 20337484 MOAD: Kd=0.18uM
    PDBbind: -logKd/Ki=6.74, Kd=0.18uM
    BindingDB: Kd=370nM, IC50=400nM
    7 3rgf:A (2.2) BS01 BAX 2.7.11.22
    2.7.11.23    		 GO:0004672 ... P49336 21806996 MOAD: ic50=0.13uM
    BindingDB: Kd=310nM, IC50=1620nM
    8 3wze:A (1.9) BS01 BAX 2.7.10.1 GO:0004672 ... P35968 25589937 MOAD: Kd=33nM
    BindingDB: IC50=90nM, Kd=59nM, Ki=22nM, EC50=500nM
    9 4asd:A (2.03) BS01 BAX 2.7.10.1 GO:0004672 ... P35968 22988103 MOAD: Ki=0.52nM
    PDBbind: -logKd/Ki=9.28, Ki=0.52nM
    BindingDB: IC50=90nM, Kd=59nM, Ki=22nM, EC50=500nM
    10 5hi2:A (2.512) BS01 BAX 2.7.11.1 GO:0004672 ... P15056 26996308 BindingDB: IC50=22nM, Kd=260nM, Ki=22nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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