Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 31 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2c47:A (2.4) BS01 5ID 2.7.11.1 GO:0004672 ... P78368 N/A
    2 2c47:B (2.4) BS01 5ID 2.7.11.1 GO:0004672 ... P78368 N/A
    3 2c47:C (2.4) BS01 5ID 2.7.11.1 GO:0004672 ... P78368 N/A
    4 2c47:D (2.4) BS01 5ID 2.7.11.1 GO:0004672 ... P78368 N/A
    5 2vuw:A (1.8) BS01 5ID 2.7.11.1 GO:0004672 ... Q8TF76 19918057
    6 2zoq:A (2.39) BS01 5ID 2.7.11.24 GO:0000165 ... P27361 18983981 MOAD: ic50=0.9uM
    PDBbind: -logKd/Ki=6.05, IC50=0.9uM
    7 2zoq:B (2.39) BS01 5ID 2.7.11.24 GO:0000165 ... P27361 18983981 MOAD: ic50=0.9uM
    8 3iq7:A (2.0) BS02 5ID 2.7.11.1 GO:0004672 ... Q8TF76 19918057
    9 3uwp:A (2.05) BS01 5ID 2.1.1.360 GO:0031151 ... Q8TEK3 23250418 BindingDB: IC50=7000nM
    10 4ouc:A (1.9) BS02 5ID 2.7.11.1 GO:0004672 ... Q8TF76 24732914
    11 5ax3:A (2.984) BS02 5ID 2.7.11.24 GO:0000165 ... P28482 26733474 PDBbind: -logKd/Ki=5.92, IC50=1.2uM
    BindingDB: Ki=530nM, IC50=1200nM
    12 5od2:A (1.98) BS02 5ID 2.7.1.146
    2.7.1.147    		 GO:0000287 ... Q58999 29352744 MOAD: Ki=0.74mM
    13 5od2:B (1.98) BS02 5ID 2.7.1.146
    2.7.1.147    		 GO:0000287 ... Q58999 29352744 MOAD: Ki=0.74mM
    14 5od2:C (1.98) BS02 5ID 2.7.1.146
    2.7.1.147    		 GO:0000287 ... Q58999 29352744 MOAD: Ki=0.74mM
    15 6c67:A (2.11) BS01 5ID 2.7.1.20 GO:0000287 ... P9WID5 31002508 BindingDB: Ki=210nM, IC50=1200nM
    16 6c67:A (2.11) BS02 5ID 2.7.1.20 GO:0000287 ... P9WID5 31002508 BindingDB: Ki=210nM, IC50=1200nM
    17 6c67:B (2.11) BS01 5ID 2.7.1.20 GO:0000287 ... P9WID5 31002508 BindingDB: Ki=210nM, IC50=1200nM
    18 6c67:B (2.11) BS02 5ID 2.7.1.20 GO:0000287 ... P9WID5 31002508 BindingDB: Ki=210nM, IC50=1200nM
    19 6g33:A (2.05) BS01 5ID 2.7.12.1 GO:0004672 ... P49759 29601130 MOAD: Kd~7nM
    PDBbind: -logKd/Ki=8.15, Kd~7nM
    20 6g33:B (2.05) BS01 5ID 2.7.12.1 GO:0004672 ... P49759 29601130 MOAD: Kd~7nM
    21 6g33:C (2.05) BS01 5ID 2.7.12.1 GO:0004672 ... P49759 29601130 MOAD: Kd~7nM
    22 6g34:A (1.76) BS01 5ID 2.7.11.1 GO:0004672 ... Q8TF76 29601130 MOAD: Kd=5.7nM
    PDBbind: -logKd/Ki=8.24, Kd=5.7nM
    23 6g39:A (1.45) BS01 5ID 2.7.11.1 GO:0004672 ... Q8TF76 29601130 PDBbind: -logKd/Ki=8.34, Kd=4.6nM
    24 6g3a:A (1.43) BS01 5ID 2.7.11.1 GO:0004672 ... Q8TF76 29601130 PDBbind: -logKd/Ki=8.38, Kd=4.2nM
    25 6jwa:A (1.781) BS01 5ID 2.7.11.1 GO:0004672 ... P68400 31282872 MOAD: ic50=10.9uM
    26 7w5o:A (2.35) BS01 5ID 2.7.11.24 GO:0000165 ... P28482 35063772
    27 7x4u:A (1.98) BS01 5ID 2.7.11.24 GO:0000165 ... P28482 N/A
    28 7xc1:A (2.09) BS01 5ID 2.7.11.24 GO:0000165 ... P28482 N/A
    29 7xc1:B (2.09) BS02 5ID 2.7.11.24 GO:0000165 ... P28482 N/A
    30 8ov3:A (1.82) BS01 5ID 2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-    		 GO:0004483 ... P0DTD1 N/A
    31 8zjv:A (1.8) BS01 5ID 2.7.11.24 GO:0000165 ... P28482 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218