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BioLiP
Download all results in tab-seperated text for 11 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 4n1u:A (1.6) BS01 2GE 3.6.1.-
    3.6.1.56    		 GO:0001669 ... P36639 24695224 MOAD: ic50=5nM
    PDBbind: -logKd/Ki=8.30, IC50=5.0nM
    BindingDB: IC50=5.0nM, EC50=126nM
    2 4n1u:B (1.6) BS01 2GE 3.6.1.-
    3.6.1.56    		 GO:0001669 ... P36639 24695224 MOAD: ic50=5nM
    BindingDB: IC50=5.0nM, EC50=126nM
    3 5hzx:A (1.9) BS01 2GE 3.6.1.-
    3.6.1.56    		 GO:0003723 ... Q7ZWC3 26862114 MOAD: ic50=2.8nM
    PDBbind: -logKd/Ki=8.55, IC50=2.8nM
    4 5hzx:B (1.9) BS01 2GE 3.6.1.-
    3.6.1.56    		 GO:0003723 ... Q7ZWC3 26862114 MOAD: ic50=2.8nM
    5 5mzg:A (1.85) BS01 2GE 3.6.1.-
    3.6.1.56    		 GO:0001669 ... P53368 29281266 MOAD: ic50=138nM
    PDBbind: -logKd/Ki=6.86, IC50=138nM
    6 5mzg:B (1.85) BS01 2GE 3.6.1.-
    3.6.1.56    		 GO:0001669 ... P53368 29281266 MOAD: ic50=138nM
    7 6ehh:A (2.4) BS01 2GE 3.6.1.-
    3.6.1.56    		 GO:0001669 ... P53368 29281266 MOAD: ic50=32nM
    PDBbind: -logKd/Ki=7.49, IC50=32nM
    8 6ehh:B (2.4) BS01 2GE 3.6.1.-
    3.6.1.56    		 GO:0001669 ... P53368 29281266 MOAD: ic50=32nM
    9 6ehh:C (2.4) BS01 2GE 3.6.1.-
    3.6.1.56    		 GO:0001669 ... P53368 29281266 MOAD: ic50=32nM
    10 6ehh:D (2.4) BS01 2GE 3.6.1.-
    3.6.1.56    		 GO:0001669 ... P53368 29281266 MOAD: ic50=32nM
    11 6qqn:B (2.301) BS02 2GE ? GO:0000226 ... Q6B856 31302152
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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