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BioLiP
Download all results in tab-seperated text for 21 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 4ji9:A (2.4) BS01 1M3 2.7.10.2 GO:0004672 ... O60674 23870430 BindingDB: IC50=6.0nM
    2 4ji9:B (2.4) BS01 1M3 2.7.10.2 GO:0004672 ... O60674 23870430 BindingDB: IC50=6.0nM
    3 4o76:A (1.7) BS01 1M3 ? N/A O60885 24568369 MOAD: ic50=0.13uM
    PDBbind: -logKd/Ki=6.89, IC50=0.13uM
    BindingDB: IC50=130nM, Kd=123nM
    4 4o76:A (1.7) BS02 1M3 ? N/A O60885 24568369 MOAD: ic50=0.13uM
    PDBbind: -logKd/Ki=6.89, IC50=0.13uM
    BindingDB: IC50=130nM, Kd=123nM
    5 4o76:B (1.7) BS01 1M3 ? N/A O60885 24568369 MOAD: ic50=0.13uM
    BindingDB: IC50=130nM, Kd=123nM
    6 4o76:C (1.7) BS01 1M3 ? N/A O60885 24568369 MOAD: ic50=0.13uM
    BindingDB: IC50=130nM, Kd=123nM
    7 4o76:C (1.7) BS02 1M3 ? N/A O60885 24568369 MOAD: ic50=0.13uM
    BindingDB: IC50=130nM, Kd=123nM
    8 4o76:D (1.7) BS01 1M3 ? N/A O60885 24568369 MOAD: ic50=0.13uM
    BindingDB: IC50=130nM, Kd=123nM
    9 4o76:D (1.7) BS02 1M3 ? N/A O60885 24568369 MOAD: ic50=0.13uM
    BindingDB: IC50=130nM, Kd=123nM
    10 5hez:A (2.66) BS02 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    11 5hez:A (2.66) BS03 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    12 5hez:A (2.66) BS04 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    13 5hez:B (2.66) BS01 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    14 5hez:B (2.66) BS02 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    15 5hez:B (2.66) BS04 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    16 5hez:C (2.66) BS01 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    17 5hez:C (2.66) BS03 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    18 5hez:C (2.66) BS04 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    19 5hez:D (2.66) BS01 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    20 5hez:D (2.66) BS02 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    21 5hez:D (2.66) BS03 1M3 2.7.10.2 GO:0004672 ... O60674 27807284 BindingDB: IC50=6.0nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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